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The map label for this gene is yisQ [H]

Identifier: 52784949

GI number: 52784949

Start: 1184998

End: 1186338

Strand: Reverse

Name: yisQ [H]

Synonym: BLi01177

Alternate gene names: 52784949

Gene position: 1186338-1184998 (Counterclockwise)

Preceding gene: 52784961

Following gene: 52784948

Centisome position: 28.09

GC content: 47.58

Gene sequence:

>1341_bases
ATGAAAAAAACAGCACCTCAAAACCTCTCTTTATTCGCATTGACTTGGCCTATCTTTATCGAGGTTTCATTATATATGTT
AATGGGCAACGCAGATACCCTGATGCTCAGCCAATATTCCGACGACAGCGTGGCAGCCGTCGGCGTCAGCAACCAAATGC
TGAACTTGATCATTGTGATGTTCGGTTTTATCGCAACAGGAACAACCGTCATTATTTCTCAATTTTTAGGGGCGCGGCAA
AAAGCCGAAGCAATGGAAGTCGGCTATGTTTCCATCAGCGCCAATTTTATCATCAGTCTATTCATCAGTGCGGCGATTTA
TATATTTGCCAAACCGCTTTTATTGATGATGGGCCTTTCCGCCAACCTGCTTGCTGAAGCCGGCATCTTTCTCCAGATCG
TCGGCGGACTGTCCTTTGTCCAAGCGCTCATTATGACGTTCAGCGCCATTTTGAAAAGCTACGGGTATACAAAGGACACA
ATGGTTGTAACCATCGGCATGAATATCCTGAACATCGCCGGCAACTATCTTGTCATATTCGGACCGTTCGGCTTTCCGGT
TTTAGGCGTGGCCGGCGTGGCAATGTCCACTTCAATCGCGCGCATCATCGGCCTTTTGGCGATCGCTCTGCTCGTCAAAA
AGCGCGTCGGCATGCCGCTGTTGTCCAAACGGCTGTTTGTCTTAAAGAAAAGTCACCTGAAAAAACTGCTGAAAATCGGG
ATTCCTTCAGCAGGGGAGCAGCTGTCATATAACGCGTCACAGATGATTGTCACCTATTTTATCACGCTGATGGGCGCGCA
GGCGCTGACAACAAAAGTCTATACCCAAAATTTGATGATGTTTATCATGCTTTTCGGCACAGCGATCAGCCAGGGAACGC
AAATCTTAATCGGACGCCATATCGGCGCGAAGCAATTTGATGAAGCATACAGCCGCTGCCTGAAAAGCCTGTGGTGGGCT
CTGGCCATTACAACATTTACTTCCGTTCTCTTCGCTGTGTTTTCAAAACAGCTGATCGGCATTTTCAGCAGCAATCCCGA
TATTATCGCAACGGCCAGTATACTGATCCTTTTGACGATTATCTTGGAGCCCGGCCGCTCGTTTAACGTGGTCATCATTA
ATTCTCTCAGAGCTGCGGGAGACGCGAAATATCCGGTTTATATGGCGATTGTCTCGATGTGGGGAATCGGACTTCCGATC
GCTTACATTTTCGGCATTCAGCTCGGATTCGGCCTGGCGGGAATTTGGTTTTCCTTCATCGCCGACGAATGGGTCAGGGG
AATTTTAATGTACAGAAGATGGAGATCTAAAATGTGGCTTCAAAAAGGATTTGCAGCATAA

Upstream 100 bases:

>100_bases
AGTCGGATTTCTCCAAGAAGTATCGGTTTCGTCTCTTCTTATTATAAGAAAATGGCGTTACACTATAAAACGGAATTTTA
AAAGAAAGGGGTCAAACGCC

Downstream 100 bases:

>100_bases
CCTGCTTTCAGTTGAAAGCAGGTTTTTTCATGTTATAAAACTTAACGAGACTGCCATTCTATGAACACAGACCTCTCAAA
GAATAGGTCTAATAGATTAA

Product: YisQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MKKTAPQNLSLFALTWPIFIEVSLYMLMGNADTLMLSQYSDDSVAAVGVSNQMLNLIIVMFGFIATGTTVIISQFLGARQ
KAEAMEVGYVSISANFIISLFISAAIYIFAKPLLLMMGLSANLLAEAGIFLQIVGGLSFVQALIMTFSAILKSYGYTKDT
MVVTIGMNILNIAGNYLVIFGPFGFPVLGVAGVAMSTSIARIIGLLAIALLVKKRVGMPLLSKRLFVLKKSHLKKLLKIG
IPSAGEQLSYNASQMIVTYFITLMGAQALTTKVYTQNLMMFIMLFGTAISQGTQILIGRHIGAKQFDEAYSRCLKSLWWA
LAITTFTSVLFAVFSKQLIGIFSSNPDIIATASILILLTIILEPGRSFNVVIINSLRAAGDAKYPVYMAIVSMWGIGLPI
AYIFGIQLGFGLAGIWFSFIADEWVRGILMYRRWRSKMWLQKGFAA

Sequences:

>Translated_446_residues
MKKTAPQNLSLFALTWPIFIEVSLYMLMGNADTLMLSQYSDDSVAAVGVSNQMLNLIIVMFGFIATGTTVIISQFLGARQ
KAEAMEVGYVSISANFIISLFISAAIYIFAKPLLLMMGLSANLLAEAGIFLQIVGGLSFVQALIMTFSAILKSYGYTKDT
MVVTIGMNILNIAGNYLVIFGPFGFPVLGVAGVAMSTSIARIIGLLAIALLVKKRVGMPLLSKRLFVLKKSHLKKLLKIG
IPSAGEQLSYNASQMIVTYFITLMGAQALTTKVYTQNLMMFIMLFGTAISQGTQILIGRHIGAKQFDEAYSRCLKSLWWA
LAITTFTSVLFAVFSKQLIGIFSSNPDIIATASILILLTIILEPGRSFNVVIINSLRAAGDAKYPVYMAIVSMWGIGLPI
AYIFGIQLGFGLAGIWFSFIADEWVRGILMYRRWRSKMWLQKGFAA
>Mature_446_residues
MKKTAPQNLSLFALTWPIFIEVSLYMLMGNADTLMLSQYSDDSVAAVGVSNQMLNLIIVMFGFIATGTTVIISQFLGARQ
KAEAMEVGYVSISANFIISLFISAAIYIFAKPLLLMMGLSANLLAEAGIFLQIVGGLSFVQALIMTFSAILKSYGYTKDT
MVVTIGMNILNIAGNYLVIFGPFGFPVLGVAGVAMSTSIARIIGLLAIALLVKKRVGMPLLSKRLFVLKKSHLKKLLKIG
IPSAGEQLSYNASQMIVTYFITLMGAQALTTKVYTQNLMMFIMLFGTAISQGTQILIGRHIGAKQFDEAYSRCLKSLWWA
LAITTFTSVLFAVFSKQLIGIFSSNPDIIATASILILLTIILEPGRSFNVVIINSLRAAGDAKYPVYMAIVSMWGIGLPI
AYIFGIQLGFGLAGIWFSFIADEWVRGILMYRRWRSKMWLQKGFAA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=437, Percent_Identity=27.9176201372998, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI48994890, Length=454, Percent_Identity=23.7885462555066, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48775; Mature: 48775

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTAPQNLSLFALTWPIFIEVSLYMLMGNADTLMLSQYSDDSVAAVGVSNQMLNLIIVM
CCCCCCCCCEEEEEHHHHHHHHHHHHEECCCCEEEEEECCCCCEEEECCHHHHHHHHHHH
FGFIATGTTVIISQFLGARQKAEAMEVGYVSISANFIISLFISAAIYIFAKPLLLMMGLS
HHHHHHHHHHHHHHHHCCHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ANLLAEAGIFLQIVGGLSFVQALIMTFSAILKSYGYTKDTMVVTIGMNILNIAGNYLVIF
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHCCCCEEEEE
GPFGFPVLGVAGVAMSTSIARIIGLLAIALLVKKRVGMPLLSKRLFVLKKSHLKKLLKIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
IPSAGEQLSYNASQMIVTYFITLMGAQALTTKVYTQNLMMFIMLFGTAISQGTQILIGRH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
IGAKQFDEAYSRCLKSLWWALAITTFTSVLFAVFSKQLIGIFSSNPDIIATASILILLTI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ILEPGRSFNVVIINSLRAAGDAKYPVYMAIVSMWGIGLPIAYIFGIQLGFGLAGIWFSFI
HHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ADEWVRGILMYRRWRSKMWLQKGFAA
HHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKTAPQNLSLFALTWPIFIEVSLYMLMGNADTLMLSQYSDDSVAAVGVSNQMLNLIIVM
CCCCCCCCCEEEEEHHHHHHHHHHHHEECCCCEEEEEECCCCCEEEECCHHHHHHHHHHH
FGFIATGTTVIISQFLGARQKAEAMEVGYVSISANFIISLFISAAIYIFAKPLLLMMGLS
HHHHHHHHHHHHHHHHCCHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ANLLAEAGIFLQIVGGLSFVQALIMTFSAILKSYGYTKDTMVVTIGMNILNIAGNYLVIF
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHCCCCEEEEE
GPFGFPVLGVAGVAMSTSIARIIGLLAIALLVKKRVGMPLLSKRLFVLKKSHLKKLLKIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
IPSAGEQLSYNASQMIVTYFITLMGAQALTTKVYTQNLMMFIMLFGTAISQGTQILIGRH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
IGAKQFDEAYSRCLKSLWWALAITTFTSVLFAVFSKQLIGIFSSNPDIIATASILILLTI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ILEPGRSFNVVIINSLRAAGDAKYPVYMAIVSMWGIGLPIAYIFGIQLGFGLAGIWFSFI
HHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ADEWVRGILMYRRWRSKMWLQKGFAA
HHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]