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The map label for this gene is gudP [H]

Identifier: 52784907

GI number: 52784907

Start: 1139406

End: 1140659

Strand: Direct

Name: gudP [H]

Synonym: BLi01135

Alternate gene names: 52784907

Gene position: 1139406-1140659 (Clockwise)

Preceding gene: 52784906

Following gene: 52784908

Centisome position: 26.98

GC content: 38.36

Gene sequence:

>1254_bases
ATGACAAAAGAGGCGGGATCAGTTGAAGGTAAAGGAAAACAACCACTGGTTCCCTATTGGGTAAAAGTTGTTATCGTATT
TTTCTTCGGTTGGGTGGCTCTTTATGCAACGCGAACAATATTAAACCCCATTATGGGGGATATTGAATCAGCGTTTTCAT
TAAGCAAGGCACAACTTGGCTTAATTATGAGTATATTTTTCATCGGTTATGCTGGTATGAATGTTCCTGCAGGAATATTA
GGAGATAAAATTGGGAAAAAACGAGTGTTGGTTCCAGGTGTTATTCTATTTGGCTCGCTTGCAGCAGTTACAGGGATGAT
GCCCACATTCTTTCTGTTTATCTCTGCATGGCTTATGGTTGGTATGGCTCAGGGGGTATATTATGGGCCGCAATATGGAA
TATCATCCGAAATTATCCCGAAGAACCGTCTAACATTAGGCAGTGCTGTGATTAATGCAGGGATGGCTTTTGGTACTTCA
ATTGGCTATTATATCTCCAGTTATGTTGTTGGAGAATGGGGATTCGGATGGGGAACCCCATTTTTTGCCATCGCAGTGCC
GGTTGTACTTATCGGCATCGCAATGGCAATTGTAATTAAAGACAAACCAAAAACTGATAAAGAGGTTAAAAGGAGCGCTG
AACCGTTTAAGTTTTCATCTTTATTTAATAGAAACTTAATTTTGGCATATATTATTATTTTCTGCTCTATTTACGGATTC
TTTATGATTATTACTTGGTTGCCATACTATTTAGAAACAGCACGCGGTTTAACCGGAGGAAATATTGCCTTTGTTGCATC
ACTTGTTCCATGGGCAGCAATTCCAGGTTCATTATTTTTTAGTTGGCTGTCAGATAAGTTAGGCCGGCGCAAACCAGTAT
TGCTCATGATGTTGCCATTTGGTATTTTATCAACAGCTGCAATTGTTTACTTTGATAGCTTACCAATTCTGTATATGACA
CTAATTGTGTATGGAATTGTAGGGAAAATTAGCGTTAACCCCGTTTTAATTGCTGTTGTAGCAAATAATGCACCAAAGCA
ATCATTAAGTACAGCATTTGGATTCTACAACTTTGTTGGAATGTTAGGTTCCATTTTAGCTCCATATATTACTGGCTGGC
TGACAGACACTACAGGAAGTATGAATATAGGATTTTATTTTGCAGCAGCTCTGTTAGTAATCGCGTTGATTGCAACATAT
TTAATAGACGAAAGTAATTTGCCATCTGTTGATAAAGCAGCTAAACATCATTAG

Upstream 100 bases:

>100_bases
ATTCTTTATGCTGCGCAGACAGATTTCGAAAAGAAACAATCTATGAAGTCTAGGATCGAAAGTCAAAGGATTAGTGGAAA
AAGTTGAAGGAGGAAGTTTG

Downstream 100 bases:

>100_bases
TTAGCAAAAGCTTATGACTTCTAGTAAATGCTCAGTCAGATTAAGTATGAAGAGACTCATTCACTGCAATTGCGCTTCAA
GCGGCACAACAAAGGCGACA

Product: hypothetical protein

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTKEAGSVEGKGKQPLVPYWVKVVIVFFFGWVALYATRTILNPIMGDIESAFSLSKAQLGLIMSIFFIGYAGMNVPAGIL
GDKIGKKRVLVPGVILFGSLAAVTGMMPTFFLFISAWLMVGMAQGVYYGPQYGISSEIIPKNRLTLGSAVINAGMAFGTS
IGYYISSYVVGEWGFGWGTPFFAIAVPVVLIGIAMAIVIKDKPKTDKEVKRSAEPFKFSSLFNRNLILAYIIIFCSIYGF
FMIITWLPYYLETARGLTGGNIAFVASLVPWAAIPGSLFFSWLSDKLGRRKPVLLMMLPFGILSTAAIVYFDSLPILYMT
LIVYGIVGKISVNPVLIAVVANNAPKQSLSTAFGFYNFVGMLGSILAPYITGWLTDTTGSMNIGFYFAAALLVIALIATY
LIDESNLPSVDKAAKHH

Sequences:

>Translated_417_residues
MTKEAGSVEGKGKQPLVPYWVKVVIVFFFGWVALYATRTILNPIMGDIESAFSLSKAQLGLIMSIFFIGYAGMNVPAGIL
GDKIGKKRVLVPGVILFGSLAAVTGMMPTFFLFISAWLMVGMAQGVYYGPQYGISSEIIPKNRLTLGSAVINAGMAFGTS
IGYYISSYVVGEWGFGWGTPFFAIAVPVVLIGIAMAIVIKDKPKTDKEVKRSAEPFKFSSLFNRNLILAYIIIFCSIYGF
FMIITWLPYYLETARGLTGGNIAFVASLVPWAAIPGSLFFSWLSDKLGRRKPVLLMMLPFGILSTAAIVYFDSLPILYMT
LIVYGIVGKISVNPVLIAVVANNAPKQSLSTAFGFYNFVGMLGSILAPYITGWLTDTTGSMNIGFYFAAALLVIALIATY
LIDESNLPSVDKAAKHH
>Mature_416_residues
TKEAGSVEGKGKQPLVPYWVKVVIVFFFGWVALYATRTILNPIMGDIESAFSLSKAQLGLIMSIFFIGYAGMNVPAGILG
DKIGKKRVLVPGVILFGSLAAVTGMMPTFFLFISAWLMVGMAQGVYYGPQYGISSEIIPKNRLTLGSAVINAGMAFGTSI
GYYISSYVVGEWGFGWGTPFFAIAVPVVLIGIAMAIVIKDKPKTDKEVKRSAEPFKFSSLFNRNLILAYIIIFCSIYGFF
MIITWLPYYLETARGLTGGNIAFVASLVPWAAIPGSLFFSWLSDKLGRRKPVLLMMLPFGILSTAAIVYFDSLPILYMTL
IVYGIVGKISVNPVLIAVVANNAPKQSLSTAFGFYNFVGMLGSILAPYITGWLTDTTGSMNIGFYFAAALLVIALIATYL
IDESNLPSVDKAAKHH

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=411, Percent_Identity=24.0875912408759, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1789152, Length=453, Percent_Identity=23.841059602649, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87082320, Length=420, Percent_Identity=23.0952380952381, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789515, Length=410, Percent_Identity=23.6585365853659, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790550, Length=372, Percent_Identity=23.3870967741935, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082071, Length=398, Percent_Identity=24.1206030150754, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI19920686, Length=418, Percent_Identity=24.8803827751196, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45253; Mature: 45122

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC
>Mature Secondary Structure 
TKEAGSVEGKGKQPLVPYWVKVVIVFFFGWVALYATRTILNPIMGDIESAFSLSKAQLG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIMSIFFIGYAGMNVPAGILGDKIGKKRVLVPGVILFGSLAAVTGMMPTFFLFISAWLMV
HHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMAQGVYYGPQYGISSEIIPKNRLTLGSAVINAGMAFGTSIGYYISSYVVGEWGFGWGTP
HHHHCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
FFAIAVPVVLIGIAMAIVIKDKPKTDKEVKRSAEPFKFSSLFNRNLILAYIIIFCSIYGF
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
FMIITWLPYYLETARGLTGGNIAFVASLVPWAAIPGSLFFSWLSDKLGRRKPVLLMMLPF
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEHHH
GILSTAAIVYFDSLPILYMTLIVYGIVGKISVNPVLIAVVANNAPKQSLSTAFGFYNFVG
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCEECCCEEEEEEECCCCHHHHHHHHHHHHHHH
MLGSILAPYITGWLTDTTGSMNIGFYFAAALLVIALIATYLIDESNLPSVDKAAKHH
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]