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The map label for this gene is comK [H]

Identifier: 52784891

GI number: 52784891

Start: 1119977

End: 1120555

Strand: Direct

Name: comK [H]

Synonym: BLi01119

Alternate gene names: 52784891

Gene position: 1119977-1120555 (Clockwise)

Preceding gene: 52784889

Following gene: 52784893

Centisome position: 26.52

GC content: 46.63

Gene sequence:

>579_bases
ATGAGCACAGAGGATATGACAAAGGATACGTATGAAGTAAACAGTTCGACAATGGCTGTCCTGCCTCTGGGAGAGGGGGA
GAAACCCGCCTCAAAAATACTTGAGACCGACAGGACTTTCCGCGTCAATATGAAGCCGTTTCAAATTATCGAAAGAAGCT
GCCGCTATTTCGGATCGAGCTATGCGGGAAGAAAAGCGGGCACATATGAAGTCATTAAAGTTTCCCATAAACCGCCGATC
ATGGTGGATCACTCAAACAACATTTTTCTTTTCCCCACATTTTCCTCAACTCGTCCTCAGTGCGGGTGGCTTTCCCATGC
GCATGTTCACGAGTTTTGCGCGGCAAAGTATGACAACACGTTTGTCACGTTTGTCAACGGGGAAACGCTGGAGCTGCCCG
TATCCATCTCATCTTTCGAAAACCAGGTTTACCGAACGGCATGGCTGAGAACAAAATTTATCGACAGGATTGAAGGAAAC
CCCATGCAGAAGAAACAGGAATTTATGCTCTATCCGAAAGAAGACCGGAATCAGCTGATATACGAATTCATCCTCAGGGA
GCTGAAAAAGCGCTATTGA

Upstream 100 bases:

>100_bases
TAAAAACATATTTTCAAATTAATTGGAAAAAATCCTGTCGTTTTGTAAAGGATAATGTTAGATTAATAGTATAAATTTAC
TAACGATTAGGAGGATCAAA

Downstream 100 bases:

>100_bases
TCTGGAGCGGCTTTGAATAAATAGTGCTCAAGAAGCGCGGATACCTGGTTGCGGATGCGGGGATTAAAGTAGTTATGCTC
TTCTTCGTAACCCTCATATA

Product: ComK

Products: NA

Alternate protein names: CTF; Competence protein K [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MSTEDMTKDTYEVNSSTMAVLPLGEGEKPASKILETDRTFRVNMKPFQIIERSCRYFGSSYAGRKAGTYEVIKVSHKPPI
MVDHSNNIFLFPTFSSTRPQCGWLSHAHVHEFCAAKYDNTFVTFVNGETLELPVSISSFENQVYRTAWLRTKFIDRIEGN
PMQKKQEFMLYPKEDRNQLIYEFILRELKKRY

Sequences:

>Translated_192_residues
MSTEDMTKDTYEVNSSTMAVLPLGEGEKPASKILETDRTFRVNMKPFQIIERSCRYFGSSYAGRKAGTYEVIKVSHKPPI
MVDHSNNIFLFPTFSSTRPQCGWLSHAHVHEFCAAKYDNTFVTFVNGETLELPVSISSFENQVYRTAWLRTKFIDRIEGN
PMQKKQEFMLYPKEDRNQLIYEFILRELKKRY
>Mature_191_residues
STEDMTKDTYEVNSSTMAVLPLGEGEKPASKILETDRTFRVNMKPFQIIERSCRYFGSSYAGRKAGTYEVIKVSHKPPIM
VDHSNNIFLFPTFSSTRPQCGWLSHAHVHEFCAAKYDNTFVTFVNGETLELPVSISSFENQVYRTAWLRTKFIDRIEGNP
MQKKQEFMLYPKEDRNQLIYEFILRELKKRY

Specific function: Intermediate regulatory gene required for the expression of the late competence genes comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes [H]

COG id: COG4903

COG function: function code K; Genetic competence transcription factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010461 [H]

Pfam domain/function: PF06338 ComK [H]

EC number: NA

Molecular weight: Translated: 22433; Mature: 22302

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEDMTKDTYEVNSSTMAVLPLGEGEKPASKILETDRTFRVNMKPFQIIERSCRYFGSS
CCCCCCCCCEEEECCCEEEEEECCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCC
YAGRKAGTYEVIKVSHKPPIMVDHSNNIFLFPTFSSTRPQCGWLSHAHVHEFCAAKYDNT
CCCCCCCCEEEEEECCCCCEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCE
FVTFVNGETLELPVSISSFENQVYRTAWLRTKFIDRIEGNPMQKKQEFMLYPKEDRNQLI
EEEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCCCHHHHH
YEFILRELKKRY
HHHHHHHHHHCC
>Mature Secondary Structure 
STEDMTKDTYEVNSSTMAVLPLGEGEKPASKILETDRTFRVNMKPFQIIERSCRYFGSS
CCCCCCCCEEEECCCEEEEEECCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCC
YAGRKAGTYEVIKVSHKPPIMVDHSNNIFLFPTFSSTRPQCGWLSHAHVHEFCAAKYDNT
CCCCCCCCEEEEEECCCCCEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCE
FVTFVNGETLELPVSISSFENQVYRTAWLRTKFIDRIEGNPMQKKQEFMLYPKEDRNQLI
EEEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCCCHHHHH
YEFILRELKKRY
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196543; 9579061; 9384377; 7783616; 11744713 [H]