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The map label for this gene is fabHB [H]

Identifier: 52784869

GI number: 52784869

Start: 1097543

End: 1098538

Strand: Reverse

Name: fabHB [H]

Synonym: BLi01097

Alternate gene names: 52784869

Gene position: 1098538-1097543 (Counterclockwise)

Preceding gene: 52784871

Following gene: 52784862

Centisome position: 26.02

GC content: 49.4

Gene sequence:

>996_bases
ATGAAAACTTTATCAAAAGCGCGAATTTCCGCCATCGGCACCTATGTTCCCGAAAAGCGCATGACAAACAAAGAGTTTGA
AAAGATCGTTGATACTTCTGATGAATGGATCATTCAGCGGACAGGAATGAAAGAAAGGCGAATCGCCGGGAGTCACGAAT
TCACATCAGATCTTTGCATAAAGGCGGTTGAAGATCTAAAAAACAGATACAGCGGCACGCTTGACGATATTGACATGATC
ATCGTCTCTACCACAACGGCGGATTACGCTTTTCCAAGCACGGCATGCCAGGTTCAGGAACACTTCGGATGGAACGAAGT
GGGCGCGGTCGATGTAAATGCGACCTGCGCAGGATTAGCGTACGGATTGCATATGGCCAACGGCCTCATCACTTCCGGAC
TGCATAGAAAAATTCTTGTGATCAGCGGGGAAACCTTATCAAAAACAACCGACTATACAGACCGCACGTCTTGCATTTTG
TTCGGAGACGGCGCAGGCGCCCTGCTTGTCGAACGGGACGACAAAGACCCAAGCTTTATTACTTTTGCCCAGGACACGAA
AGGTGACGGAGCCCGCCATTTATACAGAACCGGCTTGCGAAGCGACCTTAAAGGAGAGCCGCTTTCAGGTGAAGGGAAAA
TGGTTCAAAACGGCCGCGAAGTGTATAAGTGGGCGGTCAGGTCCGTTCCTGAAGGCGTCAAAAAACTGCTTGCCCAAGCT
GAAATGGAGCTGAAAGATATCGATTGGTTCGTCCCGCACAGCGCGAATCTGCGAATGATCGAATCGATTTGCGAAAAAAC
CGAAATTCCAGCCGAAAAAGCGCTGACAAGCGTCGAATGGTTTGGCAACACCTCATCCGCATCAATCGTTCTCGCCCTTG
ATGAAGCCGTCAAAAACGGAAAGCTGAAAAAAGGCGACACCTTGATTCTGTTCGGTTTTGGCGGGGGTCTTACATATACG
GGCCTGATTGTAAAATGGGGCGCGCCAGCTTCCTAA

Upstream 100 bases:

>100_bases
TTCCTCCCAACTTGTAATGGTTATAGTATACCTCATATCAACATTTTAGTACCAGATACTAATACTAGGTGATATAATAA
GAAAAAGGAGAGTGAATTTC

Downstream 100 bases:

>100_bases
TATCAAAAAAAACATCTTTTCTTGCCCTTGCCGGGCTTGAAAAGATGTTTTTCTTTTATGCATGCTGCTCTTCAATTTTT
CCTTTTTTCAGCAGCACTTT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 2; Beta-ketoacyl-ACP synthase III 2; KAS III 2; bFabH2 [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKTLSKARISAIGTYVPEKRMTNKEFEKIVDTSDEWIIQRTGMKERRIAGSHEFTSDLCIKAVEDLKNRYSGTLDDIDMI
IVSTTTADYAFPSTACQVQEHFGWNEVGAVDVNATCAGLAYGLHMANGLITSGLHRKILVISGETLSKTTDYTDRTSCIL
FGDGAGALLVERDDKDPSFITFAQDTKGDGARHLYRTGLRSDLKGEPLSGEGKMVQNGREVYKWAVRSVPEGVKKLLAQA
EMELKDIDWFVPHSANLRMIESICEKTEIPAEKALTSVEWFGNTSSASIVLALDEAVKNGKLKKGDTLILFGFGGGLTYT
GLIVKWGAPAS

Sequences:

>Translated_331_residues
MKTLSKARISAIGTYVPEKRMTNKEFEKIVDTSDEWIIQRTGMKERRIAGSHEFTSDLCIKAVEDLKNRYSGTLDDIDMI
IVSTTTADYAFPSTACQVQEHFGWNEVGAVDVNATCAGLAYGLHMANGLITSGLHRKILVISGETLSKTTDYTDRTSCIL
FGDGAGALLVERDDKDPSFITFAQDTKGDGARHLYRTGLRSDLKGEPLSGEGKMVQNGREVYKWAVRSVPEGVKKLLAQA
EMELKDIDWFVPHSANLRMIESICEKTEIPAEKALTSVEWFGNTSSASIVLALDEAVKNGKLKKGDTLILFGFGGGLTYT
GLIVKWGAPAS
>Mature_331_residues
MKTLSKARISAIGTYVPEKRMTNKEFEKIVDTSDEWIIQRTGMKERRIAGSHEFTSDLCIKAVEDLKNRYSGTLDDIDMI
IVSTTTADYAFPSTACQVQEHFGWNEVGAVDVNATCAGLAYGLHMANGLITSGLHRKILVISGETLSKTTDYTDRTSCIL
FGDGAGALLVERDDKDPSFITFAQDTKGDGARHLYRTGLRSDLKGEPLSGEGKMVQNGREVYKWAVRSVPEGVKKLLAQA
EMELKDIDWFVPHSANLRMIESICEKTEIPAEKALTSVEWFGNTSSASIVLALDEAVKNGKLKKGDTLILFGFGGGLTYT
GLIVKWGAPAS

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=325, Percent_Identity=37.2307692307692, Blast_Score=220, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36244; Mature: 36244

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLSKARISAIGTYVPEKRMTNKEFEKIVDTSDEWIIQRTGMKERRIAGSHEFTSDLCI
CCCHHHHHHHHHHHCCCCHHCCHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCHHHHHHH
KAVEDLKNRYSGTLDDIDMIIVSTTTADYAFPSTACQVQEHFGWNEVGAVDVNATCAGLA
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHH
YGLHMANGLITSGLHRKILVISGETLSKTTDYTDRTSCILFGDGAGALLVERDDKDPSFI
HHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCEE
TFAQDTKGDGARHLYRTGLRSDLKGEPLSGEGKMVQNGREVYKWAVRSVPEGVKKLLAQA
EEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHH
EMELKDIDWFVPHSANLRMIESICEKTEIPAEKALTSVEWFGNTSSASIVLALDEAVKNG
HCHHHHCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEEEHHHHCC
KLKKGDTLILFGFGGGLTYTGLIVKWGAPAS
CCCCCCEEEEEECCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MKTLSKARISAIGTYVPEKRMTNKEFEKIVDTSDEWIIQRTGMKERRIAGSHEFTSDLCI
CCCHHHHHHHHHHHCCCCHHCCHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCHHHHHHH
KAVEDLKNRYSGTLDDIDMIIVSTTTADYAFPSTACQVQEHFGWNEVGAVDVNATCAGLA
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHH
YGLHMANGLITSGLHRKILVISGETLSKTTDYTDRTSCILFGDGAGALLVERDDKDPSFI
HHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCEE
TFAQDTKGDGARHLYRTGLRSDLKGEPLSGEGKMVQNGREVYKWAVRSVPEGVKKLLAQA
EEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHH
EMELKDIDWFVPHSANLRMIESICEKTEIPAEKALTSVEWFGNTSSASIVLALDEAVKNG
HCHHHHCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEEEHHHHCC
KLKKGDTLILFGFGGGLTYTGLIVKWGAPAS
CCCCCCEEEEEECCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 10629181; 12737802 [H]