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The map label for this gene is yogA [H]

Identifier: 52784764

GI number: 52784764

Start: 994583

End: 995575

Strand: Reverse

Name: yogA [H]

Synonym: BLi00992

Alternate gene names: 52784764

Gene position: 995575-994583 (Counterclockwise)

Preceding gene: 52784775

Following gene: 52784756

Centisome position: 23.58

GC content: 53.27

Gene sequence:

>993_bases
ATGAAAGCGATCATCCATGAAGGAATCAAGGGCCTTTCAGGGCTGAAATATACAGACGTTTCCGACAAAACGCCCGGCCC
CGGTGAAGTCAAAATCAGGCTGAAAGCAGCCGGGCTGAACCACCGCGACTTGTTCCTTTTTCAGTCCAGAAAGGCAGGCG
ATGCCCCGTTTATTCCCGGATCCGACGGAGCAGGTATGATCGAAGAGACAGGTGAAGGCGTTCGGGACCTCGCCGTTCAT
ACAGAGGTGATCATCAATCCGAGCATCGGCTGGGAATATACGGATTCCGTTCCGCAAGTGCCGGACATTCTCGGCGGCCC
CTCTGACGGGACTTTCGCAGAGCATGTCATCGTCCCGGCGAAGCACGTGTTGAAAAAGCCGGCGCACCTTTCCTGGGAGG
AAGCAGGCGTCCTGCCTTTATCCGCTCTGACCGCTTACAGGGCTTTATTTACGAAAGGACATTTAGAAAAAGGCGAACAC
ATTCTCATACCGGGAGCCGGCGGAGGCGTCGCCACAAATGCGCTGCTCATGGCAAAGGCCGCGGGCGCGCGGGTGATTGT
AACCTCCCGAAGCGAAGAAAAAAGAAAAGAAGCGCTCCGCTATGGGGCGGACTTCGCAATTGACAGCCGCGGCCTGTGGA
AGGAAAGCTTGGATGGGGAACGGGTCGATTTAATTCTCGACAGCATCGGTCCCGCCACTTTTGCAAATTATTTCGATGTC
ATTAAACCGAACGGAAGGATCGTCATTTTCGGTGCCAGCTCTGGAGAAAGTATCCAGCTTCCGCTGCGCTCGCTCTTTTT
CCCGCAGATCAGCATCATCGGCACTTCGATGGGCAGCCTCGAAGAATTTCGGCAAATGATTGATTTTATCGAACGCCATT
CCCTTAAGCCGGTGATCGATCAAGTATTTCCTTTATCAGAAGCGGTTCCGGCCTTTAAACGGATGAAAGACGGGGAGCAG
TTTGGAAATATCGCATTGCAAATAGACGGGTAA

Upstream 100 bases:

>100_bases
AACAGAAGGCCTCTAAGCGGCCCCGGGCAAATCATTTTACATTTACCTTCATTCATGTCCATAATTTAACACAACCAACT
CGAATGGGGGGAATTTTTTT

Downstream 100 bases:

>100_bases
ACTCAGGAAACGGCGGCTTCCCTTGTCATCAGCCGCCGTTTTTTAAGCGGTGCAAGCTTCCCTTTGTTATCGCCAGAAAA
AAGGCCGCCTGAAAGAAAAA

Product: YogA

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKAIIHEGIKGLSGLKYTDVSDKTPGPGEVKIRLKAAGLNHRDLFLFQSRKAGDAPFIPGSDGAGMIEETGEGVRDLAVH
TEVIINPSIGWEYTDSVPQVPDILGGPSDGTFAEHVIVPAKHVLKKPAHLSWEEAGVLPLSALTAYRALFTKGHLEKGEH
ILIPGAGGGVATNALLMAKAAGARVIVTSRSEEKRKEALRYGADFAIDSRGLWKESLDGERVDLILDSIGPATFANYFDV
IKPNGRIVIFGASSGESIQLPLRSLFFPQISIIGTSMGSLEEFRQMIDFIERHSLKPVIDQVFPLSEAVPAFKRMKDGEQ
FGNIALQIDG

Sequences:

>Translated_330_residues
MKAIIHEGIKGLSGLKYTDVSDKTPGPGEVKIRLKAAGLNHRDLFLFQSRKAGDAPFIPGSDGAGMIEETGEGVRDLAVH
TEVIINPSIGWEYTDSVPQVPDILGGPSDGTFAEHVIVPAKHVLKKPAHLSWEEAGVLPLSALTAYRALFTKGHLEKGEH
ILIPGAGGGVATNALLMAKAAGARVIVTSRSEEKRKEALRYGADFAIDSRGLWKESLDGERVDLILDSIGPATFANYFDV
IKPNGRIVIFGASSGESIQLPLRSLFFPQISIIGTSMGSLEEFRQMIDFIERHSLKPVIDQVFPLSEAVPAFKRMKDGEQ
FGNIALQIDG
>Mature_330_residues
MKAIIHEGIKGLSGLKYTDVSDKTPGPGEVKIRLKAAGLNHRDLFLFQSRKAGDAPFIPGSDGAGMIEETGEGVRDLAVH
TEVIINPSIGWEYTDSVPQVPDILGGPSDGTFAEHVIVPAKHVLKKPAHLSWEEAGVLPLSALTAYRALFTKGHLEKGEH
ILIPGAGGGVATNALLMAKAAGARVIVTSRSEEKRKEALRYGADFAIDSRGLWKESLDGERVDLILDSIGPATFANYFDV
IKPNGRIVIFGASSGESIQLPLRSLFFPQISIIGTSMGSLEEFRQMIDFIERHSLKPVIDQVFPLSEAVPAFKRMKDGEQ
FGNIALQIDG

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=354, Percent_Identity=27.9661016949153, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI22538444, Length=354, Percent_Identity=27.9661016949153, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI24308257, Length=363, Percent_Identity=25.6198347107438, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI194239674, Length=315, Percent_Identity=25.3968253968254, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI13236495, Length=315, Percent_Identity=25.3968253968254, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI18379349, Length=333, Percent_Identity=25.2252252252252, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI194239676, Length=310, Percent_Identity=26.1290322580645, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI156627571, Length=338, Percent_Identity=24.8520710059172, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI47519420, Length=330, Percent_Identity=26.3636363636364, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI28557745, Length=243, Percent_Identity=26.3374485596708, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1786518, Length=330, Percent_Identity=24.8484848484848, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790485, Length=304, Percent_Identity=27.3026315789474, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787863, Length=289, Percent_Identity=27.3356401384083, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082401, Length=331, Percent_Identity=23.2628398791541, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082125, Length=348, Percent_Identity=24.4252873563218, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=322, Percent_Identity=25.776397515528, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71988145, Length=305, Percent_Identity=22.2950819672131, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71987554, Length=183, Percent_Identity=33.879781420765, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562876, Length=335, Percent_Identity=22.6865671641791, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562878, Length=340, Percent_Identity=23.5294117647059, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17544682, Length=353, Percent_Identity=25.2124645892351, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=333, Percent_Identity=26.7267267267267, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323729, Length=330, Percent_Identity=25.7575757575758, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=329, Percent_Identity=25.2279635258359, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=332, Percent_Identity=25.3012048192771, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319520, Length=344, Percent_Identity=24.1279069767442, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322619, Length=315, Percent_Identity=24.1269841269841, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319955, Length=315, Percent_Identity=24.1269841269841, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323099, Length=347, Percent_Identity=24.4956772334294, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581345, Length=348, Percent_Identity=25, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920632, Length=311, Percent_Identity=26.0450160771704, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221330659, Length=311, Percent_Identity=26.0450160771704, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 35604; Mature: 35604

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIIHEGIKGLSGLKYTDVSDKTPGPGEVKIRLKAAGLNHRDLFLFQSRKAGDAPFIPG
CCCHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCC
SDGAGMIEETGEGVRDLAVHTEVIINPSIGWEYTDSVPQVPDILGGPSDGTFAEHVIVPA
CCCCCCHHHHCCCHHHHHEEEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCHHHEECCC
KHVLKKPAHLSWEEAGVLPLSALTAYRALFTKGHLEKGEHILIPGAGGGVATNALLMAKA
HHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHEEEC
AGARVIVTSRSEEKRKEALRYGADFAIDSRGLWKESLDGERVDLILDSIGPATFANYFDV
CCCEEEEECCCHHHHHHHHHHCCCEEECCCCCCHHCCCCCEEEEEECCCCHHHHHHHHHE
IKPNGRIVIFGASSGESIQLPLRSLFFPQISIIGTSMGSLEEFRQMIDFIERHSLKPVID
ECCCCEEEEEECCCCCEEECCHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHH
QVFPLSEAVPAFKRMKDGEQFGNIALQIDG
HHCCHHHHHHHHHHHCCCHHHCCEEEEECC
>Mature Secondary Structure
MKAIIHEGIKGLSGLKYTDVSDKTPGPGEVKIRLKAAGLNHRDLFLFQSRKAGDAPFIPG
CCCHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCC
SDGAGMIEETGEGVRDLAVHTEVIINPSIGWEYTDSVPQVPDILGGPSDGTFAEHVIVPA
CCCCCCHHHHCCCHHHHHEEEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCHHHEECCC
KHVLKKPAHLSWEEAGVLPLSALTAYRALFTKGHLEKGEHILIPGAGGGVATNALLMAKA
HHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHEEEC
AGARVIVTSRSEEKRKEALRYGADFAIDSRGLWKESLDGERVDLILDSIGPATFANYFDV
CCCEEEEECCCHHHHHHHHHHCCCEEECCCCCCHHCCCCCEEEEEECCCCHHHHHHHHHE
IKPNGRIVIFGASSGESIQLPLRSLFFPQISIIGTSMGSLEEFRQMIDFIERHSLKPVID
ECCCCEEEEEECCCCCEEECCHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHH
QVFPLSEAVPAFKRMKDGEQFGNIALQIDG
HHCCHHHHHHHHHHHCCCHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]