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The map label for this gene is bioW [H]

Identifier: 52784565

GI number: 52784565

Start: 777572

End: 778357

Strand: Direct

Name: bioW [H]

Synonym: BLi00766

Alternate gene names: 52784565

Gene position: 777572-778357 (Clockwise)

Preceding gene: 52784564

Following gene: 52784566

Centisome position: 18.41

GC content: 51.15

Gene sequence:

>786_bases
ATGAAGGGGGAAGCGTATTACAGTGTGAGAATGAGAGCCTCCGAGAACGGTCCCCATGAAGAGGGGGGAAAACACATATC
CGGAGGAGAGCGGCTTGTGCCTTTCATCGGTTTAAATGATGCCGTCAGCGATTTATTGGAAAAAGGTATGTCTCATTCGC
GGGGCAGGCCGGACTTTATGCAAATTCAGTTCGATCTTGTAAACGAACCGATAAAGCTTGTTCAACCTTTGCGCATTGAA
ACGAATGAAACGGTATCAGCGGAAGAAGGACAAGCGCTCGCCCGTGAGCTGATCAGCCGCGCCGGCGTGCCGGAAAGCGC
GGTTGAAAAAGCGTTTCAAGGCATTGCCGAATACTGGGGCGTGAGGGGCGCCGTTTTGTTTGATATTCATTCCGGCCGGC
GGATTGACGGAAGAAAAGAAAAAGGAGTGCGCGTCTCGCGGCTCGATTGGCCGGAAGCCGATTTTCAAAGGTGGGCCGCT
TTGTGCGGGGTGCCGCCAAATCCACGGTTGAAAGAGGCGCTTGCCATCGCCTCAAAGGTATGTGAGCACCCGGCCGTCAT
CGCCGAATTATGCTGGTCGGATGACCCTGATTACATAACGGGCTATGTTGCGGCTAAAAAGCTGGGTTATCAGCGGATGA
CAAAGATGAAAGAGCATGGGGACGAAAGCGGCTGCCGGATTTTTTTTGTTGATGGATCAGCAGATGTAAAAAGCTGCATA
GACGATTTGGAAAAACAGCCTGTATTCATTGGTCAGGAGGTAAATCATGAATCAATCATTCGTTGA

Upstream 100 bases:

>100_bases
CGCGATGTTGACATATCAGGAAAGGAATACTAATATTTTATTGTAATGTTAACTCTAATTAATAATAGGTTAACATATGA
ACGAGAAGGGGGATGAAAGC

Downstream 100 bases:

>100_bases
GAAAAGCAAACAATATCTTTGGCTGCCTTTTACCCAAATGAAAGACTATGACGAAAACCCGCTGATCATCGAAAGCGGGC
AGGGAATCAAGCTGAAAGAT

Product: 6-carboxyhexanoate--CoA ligase

Products: NA

Alternate protein names: Pimeloyl-CoA synthase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKGEAYYSVRMRASENGPHEEGGKHISGGERLVPFIGLNDAVSDLLEKGMSHSRGRPDFMQIQFDLVNEPIKLVQPLRIE
TNETVSAEEGQALARELISRAGVPESAVEKAFQGIAEYWGVRGAVLFDIHSGRRIDGRKEKGVRVSRLDWPEADFQRWAA
LCGVPPNPRLKEALAIASKVCEHPAVIAELCWSDDPDYITGYVAAKKLGYQRMTKMKEHGDESGCRIFFVDGSADVKSCI
DDLEKQPVFIGQEVNHESIIR

Sequences:

>Translated_261_residues
MKGEAYYSVRMRASENGPHEEGGKHISGGERLVPFIGLNDAVSDLLEKGMSHSRGRPDFMQIQFDLVNEPIKLVQPLRIE
TNETVSAEEGQALARELISRAGVPESAVEKAFQGIAEYWGVRGAVLFDIHSGRRIDGRKEKGVRVSRLDWPEADFQRWAA
LCGVPPNPRLKEALAIASKVCEHPAVIAELCWSDDPDYITGYVAAKKLGYQRMTKMKEHGDESGCRIFFVDGSADVKSCI
DDLEKQPVFIGQEVNHESIIR
>Mature_261_residues
MKGEAYYSVRMRASENGPHEEGGKHISGGERLVPFIGLNDAVSDLLEKGMSHSRGRPDFMQIQFDLVNEPIKLVQPLRIE
TNETVSAEEGQALARELISRAGVPESAVEKAFQGIAEYWGVRGAVLFDIHSGRRIDGRKEKGVRVSRLDWPEADFQRWAA
LCGVPPNPRLKEALAIASKVCEHPAVIAELCWSDDPDYITGYVAAKKLGYQRMTKMKEHGDESGCRIFFVDGSADVKSCI
DDLEKQPVFIGQEVNHESIIR

Specific function: Transforms pimelate into pimeloyl-CoA [H]

COG id: COG1424

COG function: function code H; Pimeloyl-CoA synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BioW family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005499
- ProDom:   PD017229 [H]

Pfam domain/function: PF03744 BioW [H]

EC number: =6.2.1.14 [H]

Molecular weight: Translated: 29037; Mature: 29037

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGEAYYSVRMRASENGPHEEGGKHISGGERLVPFIGLNDAVSDLLEKGMSHSRGRPDFM
CCCCEEEEEEEECCCCCCHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCE
QIQFDLVNEPIKLVQPLRIETNETVSAEEGQALARELISRAGVPESAVEKAFQGIAEYWG
EEEHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
VRGAVLFDIHSGRRIDGRKEKGVRVSRLDWPEADFQRWAALCGVPPNPRLKEALAIASKV
CCCEEEEEECCCCCCCCCHHCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
CEHPAVIAELCWSDDPDYITGYVAAKKLGYQRMTKMKEHGDESGCRIFFVDGSADVKSCI
HHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHH
DDLEKQPVFIGQEVNHESIIR
HHHHCCCEEECCCCCHHHHCC
>Mature Secondary Structure
MKGEAYYSVRMRASENGPHEEGGKHISGGERLVPFIGLNDAVSDLLEKGMSHSRGRPDFM
CCCCEEEEEEEECCCCCCHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCE
QIQFDLVNEPIKLVQPLRIETNETVSAEEGQALARELISRAGVPESAVEKAFQGIAEYWG
EEEHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
VRGAVLFDIHSGRRIDGRKEKGVRVSRLDWPEADFQRWAALCGVPPNPRLKEALAIASKV
CCCEEEEEECCCCCCCCCHHCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
CEHPAVIAELCWSDDPDYITGYVAAKKLGYQRMTKMKEHGDESGCRIFFVDGSADVKSCI
HHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHH
DDLEKQPVFIGQEVNHESIIR
HHHHCCCEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8763940; 9387221; 9384377 [H]