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The map label for this gene is yciC [H]

Identifier: 52784564

GI number: 52784564

Start: 776204

End: 777403

Strand: Direct

Name: yciC [H]

Synonym: BLi00765

Alternate gene names: 52784564

Gene position: 776204-777403 (Clockwise)

Preceding gene: 52784563

Following gene: 52784565

Centisome position: 18.38

GC content: 49.83

Gene sequence:

>1200_bases
ATGAGTAAAAAGATTCCTGTGACAGTATTAAGCGGATACCTGGGGGCGGGTAAAACGACGCTGCTGAATCACATATTGCA
AAACCGCCAAGGGCTGAAAGTCGCCGTTATTGTTAATGACATGAGCGAAGTCAACATTGATGCAGGGCTTGTCAAGCAAG
GCGGCCTGTCGAGGACGGATGAAAAGCTGGTCGAAATGTCAAACGGCTGCATTTGCTGCACACTCAGAGAGGATTTGCTG
GTTGAAGTCGAAAAGCTGGCGAAGCAGGGAAATATTGATTATATCGTGATCGAATCGACCGGTATCAGCGAACCGATCCC
GGTCGCTCAGACGTTCTCTTACATCGACGAAGAATTGGGTATTGATTTGACCCGGTTCTGCCGCTTGGACACAATGGTGA
CGGTTGTCGACGCCAATCGTTTTTGGCACGATTTTCAGTCGGGGGACAGCCTGCTGGACCGGAAAGAGGCTGTCGGCGAA
GAGGATGAACGCGACATCGCCGATCTGCTCATCGATCAAATCGAGTTCTGCGATGTGCTGATTTTGAATAAATGCGACCT
TGTCTCCGAGGAAGATCTGCAAAAGCTTGAGAAAGTGCTGAAAACTTTGCAGCCTAAAGCAAACATCATCAGAGCGGTCA
AAGGAGAGGTCGATCCGAAGGCCGTCTTAAACACCGGTCTCTTCAATTTTGACGAAGCGAGCGGTTCAGCAGGCTGGATC
AGGGAATTAAACCAAGGACACCACCAGCATACGCCTGAGACTGAAGAATACGGAATATCTTCGTTTGTATACGAAGCGCG
CCGTCCTTTTCATACAGAGCGGTTTTATAACTGGATTCATTCGCTGCCGGAAAACGTCGTCAGGGCGAAAGGAATAGCCT
GGTGTGCGACGCGCAACACCCTTGCCCTTTTGATGTCGCAGGCGGGTCCTTCCGTGTCGCTGGAACCGATCTCTTATTGG
GTGGCCGCACTGTCCAAACCGGAACAGGAACAAATTCTCAGACAGAACCCTGAGCTTTTAAAAGAATGGAATGAAGAATT
CGGAGACCGCCATACAAAGCTCGTCTTTATCGGATTGGATCTGTCGCCGTCTGAAATTACCGCAGAAGCGGATCGATGCC
TTTTAACAGATTCGGAGATGGCGGCCGACTGGTCGCTTTTATCTGACCCGTTCGATTGGCAGATTGAAAGAGCTAGATAA

Upstream 100 bases:

>100_bases
TCATCTGGAAGCTGACGCTTTGCATTTTTAAATAAAGTGTGGTGAAATAAAATATAAATCGTAATAATTACGATTTGATA
AGAGGAAGGAGAATGAAAAA

Downstream 100 bases:

>100_bases
TTCTAAAAAAAGACAAAAGAGAGACATCTCTTTTGTCTTTTTTATTTCCAACAAACCGGTGTTTTGGACGCGATGTTGAC
ATATCAGGAAAGGAATACTA

Product: YciC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSKKIPVTVLSGYLGAGKTTLLNHILQNRQGLKVAVIVNDMSEVNIDAGLVKQGGLSRTDEKLVEMSNGCICCTLREDLL
VEVEKLAKQGNIDYIVIESTGISEPIPVAQTFSYIDEELGIDLTRFCRLDTMVTVVDANRFWHDFQSGDSLLDRKEAVGE
EDERDIADLLIDQIEFCDVLILNKCDLVSEEDLQKLEKVLKTLQPKANIIRAVKGEVDPKAVLNTGLFNFDEASGSAGWI
RELNQGHHQHTPETEEYGISSFVYEARRPFHTERFYNWIHSLPENVVRAKGIAWCATRNTLALLMSQAGPSVSLEPISYW
VAALSKPEQEQILRQNPELLKEWNEEFGDRHTKLVFIGLDLSPSEITAEADRCLLTDSEMAADWSLLSDPFDWQIERAR

Sequences:

>Translated_399_residues
MSKKIPVTVLSGYLGAGKTTLLNHILQNRQGLKVAVIVNDMSEVNIDAGLVKQGGLSRTDEKLVEMSNGCICCTLREDLL
VEVEKLAKQGNIDYIVIESTGISEPIPVAQTFSYIDEELGIDLTRFCRLDTMVTVVDANRFWHDFQSGDSLLDRKEAVGE
EDERDIADLLIDQIEFCDVLILNKCDLVSEEDLQKLEKVLKTLQPKANIIRAVKGEVDPKAVLNTGLFNFDEASGSAGWI
RELNQGHHQHTPETEEYGISSFVYEARRPFHTERFYNWIHSLPENVVRAKGIAWCATRNTLALLMSQAGPSVSLEPISYW
VAALSKPEQEQILRQNPELLKEWNEEFGDRHTKLVFIGLDLSPSEITAEADRCLLTDSEMAADWSLLSDPFDWQIERAR
>Mature_398_residues
SKKIPVTVLSGYLGAGKTTLLNHILQNRQGLKVAVIVNDMSEVNIDAGLVKQGGLSRTDEKLVEMSNGCICCTLREDLLV
EVEKLAKQGNIDYIVIESTGISEPIPVAQTFSYIDEELGIDLTRFCRLDTMVTVVDANRFWHDFQSGDSLLDRKEAVGEE
DERDIADLLIDQIEFCDVLILNKCDLVSEEDLQKLEKVLKTLQPKANIIRAVKGEVDPKAVLNTGLFNFDEASGSAGWIR
ELNQGHHQHTPETEEYGISSFVYEARRPFHTERFYNWIHSLPENVVRAKGIAWCATRNTLALLMSQAGPSVSLEPISYWV
AALSKPEQEQILRQNPELLKEWNEEFGDRHTKLVFIGLDLSPSEITAEADRCLLTDSEMAADWSLLSDPFDWQIERAR

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=288, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI126722884, Length=288, Percent_Identity=33.3333333333333, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI148727351, Length=288, Percent_Identity=32.9861111111111, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI146231952, Length=266, Percent_Identity=34.9624060150376, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI223941779, Length=223, Percent_Identity=34.9775784753363, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI223941776, Length=283, Percent_Identity=32.5088339222615, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI119120938, Length=141, Percent_Identity=42.5531914893617, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI87082430, Length=377, Percent_Identity=27.0557029177719, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788499, Length=309, Percent_Identity=26.537216828479, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324356, Length=216, Percent_Identity=32.4074074074074, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 44921; Mature: 44790

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKIPVTVLSGYLGAGKTTLLNHILQNRQGLKVAVIVNDMSEVNIDAGLVKQGGLSRTD
CCCCCCHHHECCCCCCCHHHHHHHHHCCCCCCEEEEEEECHHHCCCCCCHHCCCCCCCHH
EKLVEMSNGCICCTLREDLLVEVEKLAKQGNIDYIVIESTGISEPIPVAQTFSYIDEELG
HHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHC
IDLTRFCRLDTMVTVVDANRFWHDFQSGDSLLDRKEAVGEEDERDIADLLIDQIEFCDVL
CCHHHHHHHHHEEEEEECHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ILNKCDLVSEEDLQKLEKVLKTLQPKANIIRAVKGEVDPKAVLNTGLFNFDEASGSAGWI
EECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHH
RELNQGHHQHTPETEEYGISSFVYEARRPFHTERFYNWIHSLPENVVRAKGIAWCATRNT
HHHHCCCCCCCCCHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEECHHH
LALLMSQAGPSVSLEPISYWVAALSKPEQEQILRQNPELLKEWNEEFGDRHTKLVFIGLD
HHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEEC
LSPSEITAEADRCLLTDSEMAADWSLLSDPFDWQIERAR
CCHHHHHHHCCCEEECCCHHHHHHHHHCCCCCCEEECCC
>Mature Secondary Structure 
SKKIPVTVLSGYLGAGKTTLLNHILQNRQGLKVAVIVNDMSEVNIDAGLVKQGGLSRTD
CCCCCHHHECCCCCCCHHHHHHHHHCCCCCCEEEEEEECHHHCCCCCCHHCCCCCCCHH
EKLVEMSNGCICCTLREDLLVEVEKLAKQGNIDYIVIESTGISEPIPVAQTFSYIDEELG
HHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHC
IDLTRFCRLDTMVTVVDANRFWHDFQSGDSLLDRKEAVGEEDERDIADLLIDQIEFCDVL
CCHHHHHHHHHEEEEEECHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ILNKCDLVSEEDLQKLEKVLKTLQPKANIIRAVKGEVDPKAVLNTGLFNFDEASGSAGWI
EECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHH
RELNQGHHQHTPETEEYGISSFVYEARRPFHTERFYNWIHSLPENVVRAKGIAWCATRNT
HHHHCCCCCCCCCHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEECHHH
LALLMSQAGPSVSLEPISYWVAALSKPEQEQILRQNPELLKEWNEEFGDRHTKLVFIGLD
HHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEEC
LSPSEITAEADRCLLTDSEMAADWSLLSDPFDWQIERAR
CCHHHHHHHCCCEEECCCHHHHHHHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]