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The map label for this gene is php [H]

Identifier: 52784522

GI number: 52784522

Start: 726841

End: 727725

Strand: Direct

Name: php [H]

Synonym: BLi00722

Alternate gene names: 52784522

Gene position: 726841-727725 (Clockwise)

Preceding gene: 52784521

Following gene: 52784523

Centisome position: 17.21

GC content: 35.82

Gene sequence:

>885_bases
ATGTTGAAAGACGGAATGACCTATATGCATGAACATACAACGATAGACCTTTCCAAAGTAAAAAACAATGAGGATTGTAA
GTTGGATGTATTTCCTGAAACCGTCAGAGAATTTAAAAGTTTATACGAAAAGGGCGTACGGAATATTGTTGATGTTACGA
ATATTGGAATGGGGAGAAATATTACATACGTCCAAAAAGTTGCAAAAGAAACAGGCATTAATATTGTCTTTTCAACTGGT
TTCTATCAAGATTCTTTTTACCCGATCCATGTGTTTCGTGAATCGAAAGAAAAGCTGGCAGAAAGAATGATTATGGAGAT
TGTTGAAGGAATTAGAGGAACAGATGCCAATGCCGAGGTCATCGGTGAAATTGGAACAAGTTACAATAAATGGACGGAAA
CCGAACAAAAAGTTTTTGAAGCGGTTGTTGTGGCACATAAGCAAACAAAAAAACCAATATCAACCCATACTTCCATAGGA
ACATTAGGACATGAACAAGTAGAATTTTTTAAAAAACATGAAGTTGATTTAAACCGAGTGGTGATAGGGCATGTTGATTT
ATCTGGGGATGCCGATTATATATTGAAAATGCTGAGAGAAGGTGTATATGTAGAATTCGATACAATAGGTAAAGAAAATT
ATATGCCTGATCGTGTTCGGGCCGAAATATTGAAAAAAATACAGGATAAAGGGTATATAGACAAGGTTCTGTTGTCCATG
GATATCACAAGAAAATCACATCTTGTATATAAAGGCGGGGTGGGCTATTCATATTTGATAGACACGTTTATCCCTCTCTT
GCAAACCTATGGAATAACTGGTGAATCAATTGATAAGATGTTGATTAAAAATCCTCGCGCTTTTATGAAAGGGGAGAGTG
AATGA

Upstream 100 bases:

>100_bases
GCCCAATTGCAGTTATATTGTTGGGGATTGTCGCTAATCTTCTCTATGCAGTCGGTTTATGGCAGGTTGGCTAAATCATC
GAAAGAGGGGAAGTTTCCGA

Downstream 100 bases:

>100_bases
GCATGGATACTTATCCTCTAGATAGCCTATCAATTGAAGAAGCCATGCATAGACAATTTAAATTGGTTGATGTCATGACA
AGACATTTTCGAGGAGAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MLKDGMTYMHEHTTIDLSKVKNNEDCKLDVFPETVREFKSLYEKGVRNIVDVTNIGMGRNITYVQKVAKETGINIVFSTG
FYQDSFYPIHVFRESKEKLAERMIMEIVEGIRGTDANAEVIGEIGTSYNKWTETEQKVFEAVVVAHKQTKKPISTHTSIG
TLGHEQVEFFKKHEVDLNRVVIGHVDLSGDADYILKMLREGVYVEFDTIGKENYMPDRVRAEILKKIQDKGYIDKVLLSM
DITRKSHLVYKGGVGYSYLIDTFIPLLQTYGITGESIDKMLIKNPRAFMKGESE

Sequences:

>Translated_294_residues
MLKDGMTYMHEHTTIDLSKVKNNEDCKLDVFPETVREFKSLYEKGVRNIVDVTNIGMGRNITYVQKVAKETGINIVFSTG
FYQDSFYPIHVFRESKEKLAERMIMEIVEGIRGTDANAEVIGEIGTSYNKWTETEQKVFEAVVVAHKQTKKPISTHTSIG
TLGHEQVEFFKKHEVDLNRVVIGHVDLSGDADYILKMLREGVYVEFDTIGKENYMPDRVRAEILKKIQDKGYIDKVLLSM
DITRKSHLVYKGGVGYSYLIDTFIPLLQTYGITGESIDKMLIKNPRAFMKGESE
>Mature_294_residues
MLKDGMTYMHEHTTIDLSKVKNNEDCKLDVFPETVREFKSLYEKGVRNIVDVTNIGMGRNITYVQKVAKETGINIVFSTG
FYQDSFYPIHVFRESKEKLAERMIMEIVEGIRGTDANAEVIGEIGTSYNKWTETEQKVFEAVVVAHKQTKKPISTHTSIG
TLGHEQVEFFKKHEVDLNRVVIGHVDLSGDADYILKMLREGVYVEFDTIGKENYMPDRVRAEILKKIQDKGYIDKVLLSM
DITRKSHLVYKGGVGYSYLIDTFIPLLQTYGITGESIDKMLIKNPRAFMKGESE

Specific function: Its real enzymatic activity is not yet known. It was tested for general esterase, aminopeptidase, sulfatase, phosphatase, carbonic anhydrase, phosphodiesterase, and phosphotriesterase activities with the following substrates:P- nitrophenyl acetate, L-alan

COG id: COG1735

COG function: function code R; Predicted metal-dependent hydrolase with the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphotriesterase family [H]

Homologues:

Organism=Homo sapiens, GI20070186, Length=284, Percent_Identity=30.2816901408451, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI47933341, Length=284, Percent_Identity=30.2816901408451, Blast_Score=126, Evalue=2e-29,
Organism=Escherichia coli, GI1789780, Length=286, Percent_Identity=50, Blast_Score=298, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24645325, Length=280, Percent_Identity=25, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017947
- InterPro:   IPR001559 [H]

Pfam domain/function: PF02126 PTE [H]

EC number: NA

Molecular weight: Translated: 33612; Mature: 33612

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKDGMTYMHEHTTIDLSKVKNNEDCKLDVFPETVREFKSLYEKGVRNIVDVTNIGMGRN
CCCCCCHHHHHCCEEEHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ITYVQKVAKETGINIVFSTGFYQDSFYPIHVFRESKEKLAERMIMEIVEGIRGTDANAEV
HHHHHHHHHHCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IGEIGTSYNKWTETEQKVFEAVVVAHKQTKKPISTHTSIGTLGHEQVEFFKKHEVDLNRV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHCCCCHHHHHHHHHHCCCCCEE
VIGHVDLSGDADYILKMLREGVYVEFDTIGKENYMPDRVRAEILKKIQDKGYIDKVLLSM
EEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
DITRKSHLVYKGGVGYSYLIDTFIPLLQTYGITGESIDKMLIKNPRAFMKGESE
HCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHCCCCCC
>Mature Secondary Structure
MLKDGMTYMHEHTTIDLSKVKNNEDCKLDVFPETVREFKSLYEKGVRNIVDVTNIGMGRN
CCCCCCHHHHHCCEEEHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ITYVQKVAKETGINIVFSTGFYQDSFYPIHVFRESKEKLAERMIMEIVEGIRGTDANAEV
HHHHHHHHHHCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IGEIGTSYNKWTETEQKVFEAVVVAHKQTKKPISTHTSIGTLGHEQVEFFKKHEVDLNRV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHCCCCHHHHHHHHHHCCCCCEE
VIGHVDLSGDADYILKMLREGVYVEFDTIGKENYMPDRVRAEILKKIQDKGYIDKVLLSM
EEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
DITRKSHLVYKGGVGYSYLIDTFIPLLQTYGITGESIDKMLIKNPRAFMKGESE
HCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9548740 [H]