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The map label for this gene is sipS [H]

Identifier: 52784477

GI number: 52784477

Start: 678150

End: 678698

Strand: Direct

Name: sipS [H]

Synonym: BLi00675

Alternate gene names: 52784477

Gene position: 678150-678698 (Clockwise)

Preceding gene: 52784473

Following gene: 52784478

Centisome position: 16.06

GC content: 41.53

Gene sequence:

>549_bases
ATGAAAAATAGTAGAAAAAAAGAGATCTTATCGTGGGTGAAAACACTTGTCATCGCCGCAGCGCTTGTGATGGTTTGCCG
CTATTTTCTGTTTACGCCGTCAACCGTTTTGGGAGATTCAATGTATCCGACTTTAGAGGACGGCAACATGGTCATGGTTA
GTAAGATCAGCGATATTCAGCGCTTTGATAAAATTATTTTTCACGCGCCTGATTCGGATGAAAACTATGTGAAAAGGGTG
ATCGGGCTCCCGGGAGATACGATCGAAATGAAGGATGATGTCCTTTATATAAACGGAAAAGCATACGATGAACCTTATTT
AAAGAAAAACAAGCAAAAGCTGACGCTTCATGAACATTTAACCGATAATTTCACATTGGAGAAATTAACAGGTGAACAAA
AGGTGCCGGAAGATCACTTGTTCGTGATGGGGGATAACCGTCAAAACAGCAAAGACAGCCGCTTTTTCGGATTTATCACA
ATGGACTCCGTTGTCGGCAAAGTTGAGTTCCGTTATTTCCCTTTCAATGAGATCGGCGGAATAGAATAG

Upstream 100 bases:

>100_bases
GCGCCTGCCGGTGCTTGCGGAAAGCATTCAGACGGACGGCCTGATATGATAGAAGGAGCGGAATGCCGATGAAACGATCC
GGAAGTGAAGGAGAGTACTT

Downstream 100 bases:

>100_bases
AAAACAAAAAGGCTTCCCATGATACCTAATGGGAAGTCTTTTTGTTTGTCGCAAAGTCACCAAAAGTGGTTTAAACCAAG
CCGCTATGCTTGAGCACGGC

Product: SipS

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKNSRKKEILSWVKTLVIAAALVMVCRYFLFTPSTVLGDSMYPTLEDGNMVMVSKISDIQRFDKIIFHAPDSDENYVKRV
IGLPGDTIEMKDDVLYINGKAYDEPYLKKNKQKLTLHEHLTDNFTLEKLTGEQKVPEDHLFVMGDNRQNSKDSRFFGFIT
MDSVVGKVEFRYFPFNEIGGIE

Sequences:

>Translated_182_residues
MKNSRKKEILSWVKTLVIAAALVMVCRYFLFTPSTVLGDSMYPTLEDGNMVMVSKISDIQRFDKIIFHAPDSDENYVKRV
IGLPGDTIEMKDDVLYINGKAYDEPYLKKNKQKLTLHEHLTDNFTLEKLTGEQKVPEDHLFVMGDNRQNSKDSRFFGFIT
MDSVVGKVEFRYFPFNEIGGIE
>Mature_182_residues
MKNSRKKEILSWVKTLVIAAALVMVCRYFLFTPSTVLGDSMYPTLEDGNMVMVSKISDIQRFDKIIFHAPDSDENYVKRV
IGLPGDTIEMKDDVLYINGKAYDEPYLKKNKQKLTLHEHLTDNFTLEKLTGEQKVPEDHLFVMGDNRQNSKDSRFFGFIT
MDSVVGKVEFRYFPFNEIGGIE

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 20988; Mature: 20988

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSRKKEILSWVKTLVIAAALVMVCRYFLFTPSTVLGDSMYPTLEDGNMVMVSKISDIQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEECCCCEEEEEHHHHHH
RFDKIIFHAPDSDENYVKRVIGLPGDTIEMKDDVLYINGKAYDEPYLKKNKQKLTLHEHL
HHHHHEEECCCCCHHHHHHHHCCCCCEEEECCCEEEECCCCCCCHHHHCCCCEEEHHHHC
TDNFTLEKLTGEQKVPEDHLFVMGDNRQNSKDSRFFGFITMDSVVGKVEFRYFPFNEIGG
CCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEHHHHHCEEEEEEECCHHCCC
IE
CC
>Mature Secondary Structure
MKNSRKKEILSWVKTLVIAAALVMVCRYFLFTPSTVLGDSMYPTLEDGNMVMVSKISDIQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEECCCCEEEEEHHHHHH
RFDKIIFHAPDSDENYVKRVIGLPGDTIEMKDDVLYINGKAYDEPYLKKNKQKLTLHEHL
HHHHHEEECCCCCHHHHHHHHCCCCCEEEECCCEEEECCCCCCCHHHHCCCCEEEHHHHC
TDNFTLEKLTGEQKVPEDHLFVMGDNRQNSKDSRFFGFITMDSVVGKVEFRYFPFNEIGG
CCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEHHHHHCEEEEEEECCHHCCC
IE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8801417 [H]