Click here to switch to the map view.

The map label for this gene is thiL [H]

Identifier: 52784417

GI number: 52784417

Start: 617102

End: 618085

Strand: Direct

Name: thiL [H]

Synonym: BLi00611

Alternate gene names: 52784417

Gene position: 617102-618085 (Clockwise)

Preceding gene: 52784416

Following gene: 52784418

Centisome position: 14.61

GC content: 46.65

Gene sequence:

>984_bases
ATGGACGAATTTGAATTAATTCAAAGGATTACGCCCCGTTCGCTTTCTCATCGGGAAATAGAAATCGGTATTGGAGACGA
TGCCGCTGTTTATCATACGAAGAACAATTATCAGGAGATCGTTGCAGTCGATACGATGGTCGACGGTATTCATTTTTTAT
CATCCCATTCATCGCCTGCCGATATCGGATATAAAGCATTGGCTGTGAATATTAGCGATATTGCCGCAATGGGAGGCCGA
CCCAAGTACTATCTTGTGTCAATCGCCGTTCCTTCCGGTTGGGGCGCGACGGATATTGAAGCCATGTATGAAGAAATGAA
TAAACTGGCGACACTATATGAAATGGATTTAATCGGCGGGGACACCGTATCTGCAAACGGGCCGCTCGTTTTGACCGTAA
CAGCAATCGGCGAAATTGAAAAGGGCAGATCTTGTTTAAGGAGCCATGCCGAGCCCGGTGATGTCGTTTTTGTGACGGGA
GAACTTGGCTCATCAGCTGCCGGCCTGTCTTTTATATTGGGCCAAACATCGGCGAGAGACGAGACGCAGTCTCAATACTT
TATTGAGCGGCACAAGAGGCCTGAGCCGAGGGTGGAAGCAGGTTTGATCTGTTCACGCTATCACCATGTGGCGCTTAATG
ATATCAGCGACGGGCTTGCCAGTGAATTAAATGAAATTGCTGAAGCGAGCCGTGTTTCCATTGACATATATAAAGAGTTG
ATTCCGGTCCATTCGGATTTACATATATTGCACACAAAATGGGAAGAGTGGGTCCTTTTCGGCGGCGAGGATTTTGAACT
CGTCGGTACGATTTCTAATGATCAATGGGAACGTTTTAGTCAGGAATGCTCCGAGCATGATGTGCGGGTTCATCAAATCG
GCCGCGTCACAAAACAAGGACAGGCGGAAGTGTTTTATCATGACGGACAGGACCGCGTTCTTCTCGAAAAAAAAGGATAT
AACCATTTTAAACAAGACAGGTGA

Upstream 100 bases:

>100_bases
GAAGCTCGAATTTCTTTATTCCTTGGATAATTGGTGAGAATTCGATAAACTAATGATAGTGTTTTGATTGGTTTGCAACA
GCAAAGGAGCAAATGATCTT

Downstream 100 bases:

>100_bases
CAAGTAAAGTGAAAACGTTAGAGTGGAAAACGACAGAGCCTGAAGAGACAAAAAACATTGCCAGGCTGGCGGCAAAATAT
GTTCAGCCCGGTGATGTCAT

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MDEFELIQRITPRSLSHREIEIGIGDDAAVYHTKNNYQEIVAVDTMVDGIHFLSSHSSPADIGYKALAVNISDIAAMGGR
PKYYLVSIAVPSGWGATDIEAMYEEMNKLATLYEMDLIGGDTVSANGPLVLTVTAIGEIEKGRSCLRSHAEPGDVVFVTG
ELGSSAAGLSFILGQTSARDETQSQYFIERHKRPEPRVEAGLICSRYHHVALNDISDGLASELNEIAEASRVSIDIYKEL
IPVHSDLHILHTKWEEWVLFGGEDFELVGTISNDQWERFSQECSEHDVRVHQIGRVTKQGQAEVFYHDGQDRVLLEKKGY
NHFKQDR

Sequences:

>Translated_327_residues
MDEFELIQRITPRSLSHREIEIGIGDDAAVYHTKNNYQEIVAVDTMVDGIHFLSSHSSPADIGYKALAVNISDIAAMGGR
PKYYLVSIAVPSGWGATDIEAMYEEMNKLATLYEMDLIGGDTVSANGPLVLTVTAIGEIEKGRSCLRSHAEPGDVVFVTG
ELGSSAAGLSFILGQTSARDETQSQYFIERHKRPEPRVEAGLICSRYHHVALNDISDGLASELNEIAEASRVSIDIYKEL
IPVHSDLHILHTKWEEWVLFGGEDFELVGTISNDQWERFSQECSEHDVRVHQIGRVTKQGQAEVFYHDGQDRVLLEKKGY
NHFKQDR
>Mature_327_residues
MDEFELIQRITPRSLSHREIEIGIGDDAAVYHTKNNYQEIVAVDTMVDGIHFLSSHSSPADIGYKALAVNISDIAAMGGR
PKYYLVSIAVPSGWGATDIEAMYEEMNKLATLYEMDLIGGDTVSANGPLVLTVTAIGEIEKGRSCLRSHAEPGDVVFVTG
ELGSSAAGLSFILGQTSARDETQSQYFIERHKRPEPRVEAGLICSRYHHVALNDISDGLASELNEIAEASRVSIDIYKEL
IPVHSDLHILHTKWEEWVLFGGEDFELVGTISNDQWERFSQECSEHDVRVHQIGRVTKQGQAEVFYHDGQDRVLLEKKGY
NHFKQDR

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=327, Percent_Identity=37.3088685015291, Blast_Score=193, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 36460; Mature: 36460

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEFELIQRITPRSLSHREIEIGIGDDAAVYHTKNNYQEIVAVDTMVDGIHFLSSHSSPA
CCHHHHHHHCCCCCCCCCEEEEECCCCCEEEECCCCCCCEEEHHHHHHHHHHHHCCCCCC
DIGYKALAVNISDIAAMGGRPKYYLVSIAVPSGWGATDIEAMYEEMNKLATLYEMDLIGG
CCCEEEEEEEHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DTVSANGPLVLTVTAIGEIEKGRSCLRSHAEPGDVVFVTGELGSSAAGLSFILGQTSARD
CEECCCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEECCCCCCC
ETQSQYFIERHKRPEPRVEAGLICSRYHHVALNDISDGLASELNEIAEASRVSIDIYKEL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPVHSDLHILHTKWEEWVLFGGEDFELVGTISNDQWERFSQECSEHDVRVHQIGRVTKQG
HCCCCCEEEEEECCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCC
QAEVFYHDGQDRVLLEKKGYNHFKQDR
CEEEEEECCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MDEFELIQRITPRSLSHREIEIGIGDDAAVYHTKNNYQEIVAVDTMVDGIHFLSSHSSPA
CCHHHHHHHCCCCCCCCCEEEEECCCCCEEEECCCCCCCEEEHHHHHHHHHHHHCCCCCC
DIGYKALAVNISDIAAMGGRPKYYLVSIAVPSGWGATDIEAMYEEMNKLATLYEMDLIGG
CCCEEEEEEEHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DTVSANGPLVLTVTAIGEIEKGRSCLRSHAEPGDVVFVTGELGSSAAGLSFILGQTSARD
CEECCCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEECCCCCCC
ETQSQYFIERHKRPEPRVEAGLICSRYHHVALNDISDGLASELNEIAEASRVSIDIYKEL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPVHSDLHILHTKWEEWVLFGGEDFELVGTISNDQWERFSQECSEHDVRVHQIGRVTKQG
HCCCCCEEEEEECCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCC
QAEVFYHDGQDRVLLEKKGYNHFKQDR
CEEEEEECCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377; 8419296 [H]