Click here to switch to the map view.

The map label for this gene is rsbS [H]

Identifier: 52784375

GI number: 52784375

Start: 560773

End: 561138

Strand: Direct

Name: rsbS [H]

Synonym: BLi00555

Alternate gene names: 52784375

Gene position: 560773-561138 (Clockwise)

Preceding gene: 52784374

Following gene: 52784376

Centisome position: 13.28

GC content: 46.99

Gene sequence:

>366_bases
TTGAGGGTACCTAACATTCCAATTTTGAAGCTGTATAACTGTTTATTGGTATCCATTCAAGTAGAGCTCGATGACCAAAC
CGCTCTGAAATTCCAAGAGGACCTGCTGAACAAAATATATGAAACCGGTTCGAACGGAGTGGTGATCGATCTGACTTCAG
TGGACATCATCGATTCATTCATCGCCAAAGTCCTTGGCGATGTCATTACAATGTCAAAACTGATGGGCGCCAAAGTCGTT
CTGACTGGCATCCAGCCGGCTGTTGCGGTGACATTGATTGAACTCGGCATTTCTTTGGACGAGATCGAGACGGCGCTCGA
TCTCGAAAAGGGGCTCGAGACATTGCAGCGGGAATTGGGGGAATAA

Upstream 100 bases:

>100_bases
CGATTTAACTCAGGTTATTACAAAAAATACCCTGCAAAAAGGAATTCAAACCGCATTAGAAATGACAGACAGAAAAATTG
TTTCATTGGAGGAATAATCT

Downstream 100 bases:

>100_bases
ATATGGCAGACCAATCCTGTGTGAAGATTTTGACTGAATGGGACATAGTGGCCGCCAGACAGCTTGGGCGAAATGTCGCA
AAAGAACTGGGGTTCGGCAC

Product: RsbS

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MRVPNIPILKLYNCLLVSIQVELDDQTALKFQEDLLNKIYETGSNGVVIDLTSVDIIDSFIAKVLGDVITMSKLMGAKVV
LTGIQPAVAVTLIELGISLDEIETALDLEKGLETLQRELGE

Sequences:

>Translated_121_residues
MRVPNIPILKLYNCLLVSIQVELDDQTALKFQEDLLNKIYETGSNGVVIDLTSVDIIDSFIAKVLGDVITMSKLMGAKVV
LTGIQPAVAVTLIELGISLDEIETALDLEKGLETLQRELGE
>Mature_121_residues
MRVPNIPILKLYNCLLVSIQVELDDQTALKFQEDLLNKIYETGSNGVVIDLTSVDIIDSFIAKVLGDVITMSKLMGAKVV
LTGIQPAVAVTLIELGISLDEIETALDLEKGLETLQRELGE

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 13199; Mature: 13199

Theoretical pI: Translated: 3.99; Mature: 3.99

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVPNIPILKLYNCLLVSIQVELDDQTALKFQEDLLNKIYETGSNGVVIDLTSVDIIDSF
CCCCCCHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHH
IAKVLGDVITMSKLMGAKVVLTGIQPAVAVTLIELGISLDEIETALDLEKGLETLQRELG
HHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
E
C
>Mature Secondary Structure
MRVPNIPILKLYNCLLVSIQVELDDQTALKFQEDLLNKIYETGSNGVVIDLTSVDIIDSF
CCCCCCHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHH
IAKVLGDVITMSKLMGAKVVLTGIQPAVAVTLIELGISLDEIETALDLEKGLETLQRELG
HHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]