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The map label for this gene is rsbR [H]

Identifier: 52784374

GI number: 52784374

Start: 559942

End: 560769

Strand: Direct

Name: rsbR [H]

Synonym: BLi00554

Alternate gene names: 52784374

Gene position: 559942-560769 (Clockwise)

Preceding gene: 52784373

Following gene: 52784375

Centisome position: 13.26

GC content: 46.01

Gene sequence:

>828_bases
ATGTCGAATCAAGCGGTGTTAAAATTTATCTCGGAACACCAAAATGTACTCGCCGGGAATTTGGCGGATATTCTGAAAGA
CTTAAACAGCAACATGACAAACGTGAAGCTGACTGAACACATGTATGAGACGATCAGCAATGAATATATTCATATCCTCA
TGAATGAGTCCGGGGACGGGAATGAAAAATCGATCGACACCATCTACCAGTTCTCTTCAAAAGCCGTACAGCTCGGCGTT
CCGCTGAAGCTGCTGTCGTCGGGATTATCAGCTTTTTGGAAGCACCTTTACTATGAAATGAACAAGGATGTGCCGGAAGA
TCAGCAGTGCTATGATTTGATTTGGGAAATCGATAAATTTATCGAACCGATCAACAGCGAAATCTTGAATCAGTATGCGA
TCTCCTGGGAGAAAACCGTTGCTCTGCAAAAGGTCGCATTACAGGAGCTCTCGGCGCCGCTGATCCCGGTTTTTGAAAAT
ATTACGGTGATGCCGCTTGTCGGCACGATCGATACGGAGCGGGCCAAAAAGATTATGGAAAACCTGTTGAGCGGCGTCGT
CAAACACCGGTCTGAAGTCGTGCTCATTGACATTACGGGCGTGCCTGTCGTCGATACGATGGTCGCACACCACATCATGC
AGGCTTCCGAAGCCGTCAGACTTGTCGGAGCTAAATGCCTGCTCGTCGGAATCCGCCCGGAAATCGCGCAGACGATTGTG
AATTTGGGAATCGATTTAACTCAGGTTATTACAAAAAATACCCTGCAAAAAGGAATTCAAACCGCATTAGAAATGACAGA
CAGAAAAATTGTTTCATTGGAGGAATAA

Upstream 100 bases:

>100_bases
CGAGGCGAAAGAGCAACTTTTTTTGTGTTCAAAAATAACAAACGATATAATGGAACTGTTAGTCCAAAAAATGTTATCAG
ATGTAGTCAGGGGGATGAAC

Downstream 100 bases:

>100_bases
TCTTTGAGGGTACCTAACATTCCAATTTTGAAGCTGTATAACTGTTTATTGGTATCCATTCAAGTAGAGCTCGATGACCA
AACCGCTCTGAAATTCCAAG

Product: hypothetical protein

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSNQAVLKFISEHQNVLAGNLADILKDLNSNMTNVKLTEHMYETISNEYIHILMNESGDGNEKSIDTIYQFSSKAVQLGV
PLKLLSSGLSAFWKHLYYEMNKDVPEDQQCYDLIWEIDKFIEPINSEILNQYAISWEKTVALQKVALQELSAPLIPVFEN
ITVMPLVGTIDTERAKKIMENLLSGVVKHRSEVVLIDITGVPVVDTMVAHHIMQASEAVRLVGAKCLLVGIRPEIAQTIV
NLGIDLTQVITKNTLQKGIQTALEMTDRKIVSLEE

Sequences:

>Translated_275_residues
MSNQAVLKFISEHQNVLAGNLADILKDLNSNMTNVKLTEHMYETISNEYIHILMNESGDGNEKSIDTIYQFSSKAVQLGV
PLKLLSSGLSAFWKHLYYEMNKDVPEDQQCYDLIWEIDKFIEPINSEILNQYAISWEKTVALQKVALQELSAPLIPVFEN
ITVMPLVGTIDTERAKKIMENLLSGVVKHRSEVVLIDITGVPVVDTMVAHHIMQASEAVRLVGAKCLLVGIRPEIAQTIV
NLGIDLTQVITKNTLQKGIQTALEMTDRKIVSLEE
>Mature_274_residues
SNQAVLKFISEHQNVLAGNLADILKDLNSNMTNVKLTEHMYETISNEYIHILMNESGDGNEKSIDTIYQFSSKAVQLGVP
LKLLSSGLSAFWKHLYYEMNKDVPEDQQCYDLIWEIDKFIEPINSEILNQYAISWEKTVALQKVALQELSAPLIPVFENI
TVMPLVGTIDTERAKKIMENLLSGVVKHRSEVVLIDITGVPVVDTMVAHHIMQASEAVRLVGAKCLLVGIRPEIAQTIVN
LGIDLTQVITKNTLQKGIQTALEMTDRKIVSLEE

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 30803; Mature: 30672

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQAVLKFISEHQNVLAGNLADILKDLNSNMTNVKLTEHMYETISNEYIHILMNESGDG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCEEEEEECCCCCC
NEKSIDTIYQFSSKAVQLGVPLKLLSSGLSAFWKHLYYEMNKDVPEDQQCYDLIWEIDKF
CCHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IEPINSEILNQYAISWEKTVALQKVALQELSAPLIPVFENITVMPLVGTIDTERAKKIME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCCHHHHHHHHH
NLLSGVVKHRSEVVLIDITGVPVVDTMVAHHIMQASEAVRLVGAKCLLVGIRPEIAQTIV
HHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHH
NLGIDLTQVITKNTLQKGIQTALEMTDRKIVSLEE
HHCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC
>Mature Secondary Structure 
SNQAVLKFISEHQNVLAGNLADILKDLNSNMTNVKLTEHMYETISNEYIHILMNESGDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCEEEEEECCCCCC
NEKSIDTIYQFSSKAVQLGVPLKLLSSGLSAFWKHLYYEMNKDVPEDQQCYDLIWEIDKF
CCHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IEPINSEILNQYAISWEKTVALQKVALQELSAPLIPVFENITVMPLVGTIDTERAKKIME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCCHHHHHHHHH
NLLSGVVKHRSEVVLIDITGVPVVDTMVAHHIMQASEAVRLVGAKCLLVGIRPEIAQTIV
HHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHH
NLGIDLTQVITKNTLQKGIQTALEMTDRKIVSLEE
HHCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]