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The map label for this gene is ydbM [H]

Identifier: 52784360

GI number: 52784360

Start: 546102

End: 547250

Strand: Direct

Name: ydbM [H]

Synonym: BLi00540

Alternate gene names: 52784360

Gene position: 546102-547250 (Clockwise)

Preceding gene: 52784359

Following gene: 52784363

Centisome position: 12.93

GC content: 51.44

Gene sequence:

>1149_bases
GTGTGTTCAATATTTGTGAAAACGGAAAGGCAGCAGGAATGGCTCGATAAAATCGGAAAATTGGCGGATGAATTTGAGAA
AACAGCAGCGTACTATGACGAACATGCACAATTTCCCGCAGAACATATTCAAAAGCTGCGGGATTCAGGCTACACAGCGC
TGACGGTCGGAAAAGATTACGGAGGAGAAGGCATTTCGCTCTACGATATGCTTTTGTTTCAGGAACGGCTTGCCAAAGGA
GACGGACCGACGGCTCTCAGCATCGGCTGGCACTTAAGCGTGATGGGGGAACTGGCGGAGGGAAACAGCTGGGACCGGGA
TGTGTTTTCATCGCTTTCCCATGAAGCATTAAAGGGCGCGCTGATCAACAGAGCGGCAAGTGAAGCGCAGACAGGCAGCC
CGACAAGAGGAGGACGCCCCGGAACCCATGCAGTCAAAAAGAACGGCGGCTGGATTGTAAACGGCCGTAAAACATTCACA
ACGATGTCTCCGGTTCTCGACTATTTTCTTGTCACCGCTTGGATTGAAGAGAAGCAAATGATCGGCGTTTTCTTGATCCA
TAAAGATGCGGAAGGCTTGGCAATAGAAGAAACGTGGGATATGGCGGCGATGAGGGGCACGGGAAGCCACGATTTGGTGC
TGACCGATGTCCGTCTGGACGAATCCATGCTTGTTGAACTGTTGGCTGGTAAAAGAACCGATAAAATCAACGGCTGGCTG
CTTCATATACCGGCTGTCTATTTAGGGATCGCACAAGCAGCGAGAGACTATGCTGTCCAATTTGCAAAAGACTATCAGCC
GAACAGCTTGAAAGGTCCGATCAAAGAGGTGCCCGCTGTTCAGCGCCATATCGGCGAAATCGATCTGGAACTCATGAAAG
CCCGCCACTTTATGTATCATGTTGCAGAGCTTTATGATGATCCGGAGCGCCGCGCCCTTTTGACAGGTGAGCTTGGAGCG
GTTAAGCACACGGTAACGAATACGGCCATTGATGTCGTAGACAAGGCGATGAGAGTCGTCGGAGCGAAAAGTCTCGCAAG
AACGAACCCGCTCCAAAGATTCTACCGCGATGTCCGGGCGGGCCTCCACAACCCGCCGATGGATGATGCGACAATCGCCA
AGCTTGCAGGAATTGCATTCAGCGAATAG

Upstream 100 bases:

>100_bases
GGGCTTTTTTGTTTTGCCAAGGCTATCATTTGCACAACGAGCCGAGAACGAACTATAATACTTATTAAATCTATCGGAAT
TTGGTCAGGAGGATGCCGGC

Downstream 100 bases:

>100_bases
TTTTGTCATTCTTTAAGCTTTAGCGGGGTGTCGATCCGCTAAAAGAAGCCGTTCAAAATCAGCGGCTTCTTTTTTATGTT
TGTTTTGCTTTTGAAATGGC

Product: YdbM

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MCSIFVKTERQQEWLDKIGKLADEFEKTAAYYDEHAQFPAEHIQKLRDSGYTALTVGKDYGGEGISLYDMLLFQERLAKG
DGPTALSIGWHLSVMGELAEGNSWDRDVFSSLSHEALKGALINRAASEAQTGSPTRGGRPGTHAVKKNGGWIVNGRKTFT
TMSPVLDYFLVTAWIEEKQMIGVFLIHKDAEGLAIEETWDMAAMRGTGSHDLVLTDVRLDESMLVELLAGKRTDKINGWL
LHIPAVYLGIAQAARDYAVQFAKDYQPNSLKGPIKEVPAVQRHIGEIDLELMKARHFMYHVAELYDDPERRALLTGELGA
VKHTVTNTAIDVVDKAMRVVGAKSLARTNPLQRFYRDVRAGLHNPPMDDATIAKLAGIAFSE

Sequences:

>Translated_382_residues
MCSIFVKTERQQEWLDKIGKLADEFEKTAAYYDEHAQFPAEHIQKLRDSGYTALTVGKDYGGEGISLYDMLLFQERLAKG
DGPTALSIGWHLSVMGELAEGNSWDRDVFSSLSHEALKGALINRAASEAQTGSPTRGGRPGTHAVKKNGGWIVNGRKTFT
TMSPVLDYFLVTAWIEEKQMIGVFLIHKDAEGLAIEETWDMAAMRGTGSHDLVLTDVRLDESMLVELLAGKRTDKINGWL
LHIPAVYLGIAQAARDYAVQFAKDYQPNSLKGPIKEVPAVQRHIGEIDLELMKARHFMYHVAELYDDPERRALLTGELGA
VKHTVTNTAIDVVDKAMRVVGAKSLARTNPLQRFYRDVRAGLHNPPMDDATIAKLAGIAFSE
>Mature_382_residues
MCSIFVKTERQQEWLDKIGKLADEFEKTAAYYDEHAQFPAEHIQKLRDSGYTALTVGKDYGGEGISLYDMLLFQERLAKG
DGPTALSIGWHLSVMGELAEGNSWDRDVFSSLSHEALKGALINRAASEAQTGSPTRGGRPGTHAVKKNGGWIVNGRKTFT
TMSPVLDYFLVTAWIEEKQMIGVFLIHKDAEGLAIEETWDMAAMRGTGSHDLVLTDVRLDESMLVELLAGKRTDKINGWL
LHIPAVYLGIAQAARDYAVQFAKDYQPNSLKGPIKEVPAVQRHIGEIDLELMKARHFMYHVAELYDDPERRALLTGELGA
VKHTVTNTAIDVVDKAMRVVGAKSLARTNPLQRFYRDVRAGLHNPPMDDATIAKLAGIAFSE

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=344, Percent_Identity=24.1279069767442, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4501859, Length=335, Percent_Identity=22.6865671641791, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=23.0563002680965, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI226958414, Length=337, Percent_Identity=23.4421364985163, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786223, Length=361, Percent_Identity=21.3296398891967, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=331, Percent_Identity=25.6797583081571, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=23.2432432432432, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=390, Percent_Identity=23.0769230769231, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=266, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356377, Length=347, Percent_Identity=23.6311239193084, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355753, Length=333, Percent_Identity=24.024024024024, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646207, Length=350, Percent_Identity=23.4285714285714, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24666513, Length=381, Percent_Identity=21.7847769028871, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 42355; Mature: 42355

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCSIFVKTERQQEWLDKIGKLADEFEKTAAYYDEHAQFPAEHIQKLRDSGYTALTVGKDY
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCC
GGEGISLYDMLLFQERLAKGDGPTALSIGWHLSVMGELAEGNSWDRDVFSSLSHEALKGA
CCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LINRAASEAQTGSPTRGGRPGTHAVKKNGGWIVNGRKTFTTMSPVLDYFLVTAWIEEKQM
HHHHHHHHCCCCCCCCCCCCCCCCEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCE
IGVFLIHKDAEGLAIEETWDMAAMRGTGSHDLVLTDVRLDESMLVELLAGKRTDKINGWL
EEEEEEEECCCCCEEEHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCEE
LHIPAVYLGIAQAARDYAVQFAKDYQPNSLKGPIKEVPAVQRHIGEIDLELMKARHFMYH
EEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
VAELYDDPERRALLTGELGAVKHTVTNTAIDVVDKAMRVVGAKSLARTNPLQRFYRDVRA
HHHHHCCHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
GLHNPPMDDATIAKLAGIAFSE
CCCCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MCSIFVKTERQQEWLDKIGKLADEFEKTAAYYDEHAQFPAEHIQKLRDSGYTALTVGKDY
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCC
GGEGISLYDMLLFQERLAKGDGPTALSIGWHLSVMGELAEGNSWDRDVFSSLSHEALKGA
CCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LINRAASEAQTGSPTRGGRPGTHAVKKNGGWIVNGRKTFTTMSPVLDYFLVTAWIEEKQM
HHHHHHHHCCCCCCCCCCCCCCCCEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCE
IGVFLIHKDAEGLAIEETWDMAAMRGTGSHDLVLTDVRLDESMLVELLAGKRTDKINGWL
EEEEEEEECCCCCEEEHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCEE
LHIPAVYLGIAQAARDYAVQFAKDYQPNSLKGPIKEVPAVQRHIGEIDLELMKARHFMYH
EEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
VAELYDDPERRALLTGELGAVKHTVTNTAIDVVDKAMRVVGAKSLARTNPLQRFYRDVRA
HHHHHCCHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
GLHNPPMDDATIAKLAGIAFSE
CCCCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]