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The map label for this gene is 52784217

Identifier: 52784217

GI number: 52784217

Start: 370023

End: 372077

Strand: Direct

Name: 52784217

Synonym: BLi00395

Alternate gene names: NA

Gene position: 370023-372077 (Clockwise)

Preceding gene: 52784213

Following gene: 52784218

Centisome position: 8.76

GC content: 49.59

Gene sequence:

>2055_bases
TTGAATGAAGAAGGTTACCGGCTTGGAATTGATATTGGAGGAACTTTTACCGATCTTACATTGTTAAATCCGGCGGACGG
AAGCATGACCGCAGTTAAAACGCCGACCGTTCCCGAAGATCCGGCCCGAGGAATCATCAACGGCTTGGCTCTCTTGAAAA
CTCGGGGTGTCCAGCCTTCAGAAATTCATCACTTTGTACACGGCATGACAATCGGTTTGAACACATTATTACAACGCAAA
GGGGCTGATATTGCTTTATTCGTAACCGAAGGTTTCCGTGATATTCTTTCGCTTCAGCGTCTCCGGCTTCCGGTACCCTA
CGATTTTAGATCTAGAATGCCGGAGCCCCTCATTCCTCGGAAAAACGTGTTTCCCATTCAAGAAAGAATGCTTTATGACG
GCTCTGAAAAGCTGCCGCTTCATATGGAAGATATCGATGAGGCGGTTGGACAAGCTTTAAGAAAAGGCTTAAAAGGAATC
GTTGTTTCTTTTTTGCACAGCTATCGGAATCCGCTCCATGAACGCCAGGCTGCCGAACGGATCAGGCAAATAGCGCCCGA
GCTTGAGGTGGCAACGTCTGCGGAGCTTTGGCCGCAAATGAGAGAATACGAACGAACGGTTATGTCCGTCGCGAATCTAT
ACATCAAACCGAATATCCATCACTACTTTGGAACGCTGAAAGAGAGGCTTGTCCAGGAAGGAATATCGGCGCAGCCGTTT
ATCACCCAGTCCAACGGAGGACTGATGGACATTGAATCGGCTGCCGAGGCACCTGTCAAAACGCTTTTTTCCGGACCGGC
AGCGGGGGTCATAGGATCCATCAGAACGGCGGAAGCCGCCGGCGAGGCCAATATCATCACCTTTGATGTCGGAGGAACCA
GCGCAGATATTTCGATTGTTGAAAAAGGAGAGCCGACCTTTACCCAGTCAAATCAAATCTCGGGATTTCCGATTGCGATT
CCATCTGTAGCAATGTATTCGATCGGTGCCGGCGGAGGATCGGTGGCATGGATTGACAGCGGCGGTCTCTTGAAAGTAGG
GCCGGAGTCAGTTGGCTCTGATCCGGGGCCGGCCTGTTACGGAAAAGGAACAAAGGCCGCACTTACAGATGCGTTTCTTA
TATGTCATTATTTAAACCCAAACAGGTTTGCAGCAGGAAATATGAAACTGTACCGGGAAAGAGCCGAAAAAGCGCTCCTC
CCGGTTGCCGAGTATTTAGGCACAGATGTGGAGCAAGCCGCGGATAAGATGATTCAAGTTGCGCTTGCCAATATGTACAC
GGAACTAAGCAATGTCATGGAGCAACACGGGTTTGACCCGCGTGAATTCAGCCTTATGGCTTTTGGAGGCGCAGGCCCGG
TTACTGCTAATTTTTTGGCTGAGGAAATTCAGGCCAAAAATGTGCTGATCCCGCCGCATCCGGGAACTCTATCGGCTTTG
GGCGCACTGACGGCTGATTTTATCTACGATGCTGTATGTTCAAGACAGGTGCTGCTTGAGCAAATAAAAACGGCTGAGTT
AAAAGTGGAGTTTATGAGGCTGCAAGAACAGGCGGAAACATGGCTGCGGAAACAACGGGCGGACATGGTGACTGAAGCCT
CTCTTCTTTACTTGCTTGATGCCCGTTATAAAGGTCAGGCGTATGAAATTGAGCTCCCTGTTTCACCGGAATGGCTGGAA
GGCGAAAGTACGAGTGAAATCGCAGACTCCTTTCATCTCTTACATGGGAAGCAATATGGACACAGCGATGGGAAAGCAAG
CATTGAATTGATGAATATGCGCGTCCGCATTATAGGCAAGACGCCGAAACCGCCAGGCGGAAAAGGATGTCAAAGTAATC
TGCCCGAAGCTGAACCTGTCAGCCAAAGAAAGATCATCATGAAAGGCGGTACATATCAAGCCTCCGTATACCGCCGTCCA
GATTTAAGGAGCGGGCAGAGAATAGATGGGCCGGCCATTGTTGAGCAGGACGATACAACGACGCTGATTTTGCCAAATTG
GAGCGGGAAAACCGATCATGCCGGAAATTTGATCATTGAACGGAAGGAGAGCTGA

Upstream 100 bases:

>100_bases
GAATATTGTAATTAAACATAATTGACTACTTTCTCATGCTTGATTAGTATGATAGTAAAATATTTTAAAAAAAGGATATT
TTTAAAAGGGGAGATCGGGA

Downstream 100 bases:

>100_bases
CCATGCGCACAGATCCTGCCCGGCTGGAAATGATGAGAAGCTACTTTAACGCGATAGCCGCGGGAATGGGGCACGTTATT
GAACGGACGTCCTTTACCAC

Product: hypothetical protein

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 684; Mature: 684

Protein sequence:

>684_residues
MNEEGYRLGIDIGGTFTDLTLLNPADGSMTAVKTPTVPEDPARGIINGLALLKTRGVQPSEIHHFVHGMTIGLNTLLQRK
GADIALFVTEGFRDILSLQRLRLPVPYDFRSRMPEPLIPRKNVFPIQERMLYDGSEKLPLHMEDIDEAVGQALRKGLKGI
VVSFLHSYRNPLHERQAAERIRQIAPELEVATSAELWPQMREYERTVMSVANLYIKPNIHHYFGTLKERLVQEGISAQPF
ITQSNGGLMDIESAAEAPVKTLFSGPAAGVIGSIRTAEAAGEANIITFDVGGTSADISIVEKGEPTFTQSNQISGFPIAI
PSVAMYSIGAGGGSVAWIDSGGLLKVGPESVGSDPGPACYGKGTKAALTDAFLICHYLNPNRFAAGNMKLYRERAEKALL
PVAEYLGTDVEQAADKMIQVALANMYTELSNVMEQHGFDPREFSLMAFGGAGPVTANFLAEEIQAKNVLIPPHPGTLSAL
GALTADFIYDAVCSRQVLLEQIKTAELKVEFMRLQEQAETWLRKQRADMVTEASLLYLLDARYKGQAYEIELPVSPEWLE
GESTSEIADSFHLLHGKQYGHSDGKASIELMNMRVRIIGKTPKPPGGKGCQSNLPEAEPVSQRKIIMKGGTYQASVYRRP
DLRSGQRIDGPAIVEQDDTTTLILPNWSGKTDHAGNLIIERKES

Sequences:

>Translated_684_residues
MNEEGYRLGIDIGGTFTDLTLLNPADGSMTAVKTPTVPEDPARGIINGLALLKTRGVQPSEIHHFVHGMTIGLNTLLQRK
GADIALFVTEGFRDILSLQRLRLPVPYDFRSRMPEPLIPRKNVFPIQERMLYDGSEKLPLHMEDIDEAVGQALRKGLKGI
VVSFLHSYRNPLHERQAAERIRQIAPELEVATSAELWPQMREYERTVMSVANLYIKPNIHHYFGTLKERLVQEGISAQPF
ITQSNGGLMDIESAAEAPVKTLFSGPAAGVIGSIRTAEAAGEANIITFDVGGTSADISIVEKGEPTFTQSNQISGFPIAI
PSVAMYSIGAGGGSVAWIDSGGLLKVGPESVGSDPGPACYGKGTKAALTDAFLICHYLNPNRFAAGNMKLYRERAEKALL
PVAEYLGTDVEQAADKMIQVALANMYTELSNVMEQHGFDPREFSLMAFGGAGPVTANFLAEEIQAKNVLIPPHPGTLSAL
GALTADFIYDAVCSRQVLLEQIKTAELKVEFMRLQEQAETWLRKQRADMVTEASLLYLLDARYKGQAYEIELPVSPEWLE
GESTSEIADSFHLLHGKQYGHSDGKASIELMNMRVRIIGKTPKPPGGKGCQSNLPEAEPVSQRKIIMKGGTYQASVYRRP
DLRSGQRIDGPAIVEQDDTTTLILPNWSGKTDHAGNLIIERKES
>Mature_684_residues
MNEEGYRLGIDIGGTFTDLTLLNPADGSMTAVKTPTVPEDPARGIINGLALLKTRGVQPSEIHHFVHGMTIGLNTLLQRK
GADIALFVTEGFRDILSLQRLRLPVPYDFRSRMPEPLIPRKNVFPIQERMLYDGSEKLPLHMEDIDEAVGQALRKGLKGI
VVSFLHSYRNPLHERQAAERIRQIAPELEVATSAELWPQMREYERTVMSVANLYIKPNIHHYFGTLKERLVQEGISAQPF
ITQSNGGLMDIESAAEAPVKTLFSGPAAGVIGSIRTAEAAGEANIITFDVGGTSADISIVEKGEPTFTQSNQISGFPIAI
PSVAMYSIGAGGGSVAWIDSGGLLKVGPESVGSDPGPACYGKGTKAALTDAFLICHYLNPNRFAAGNMKLYRERAEKALL
PVAEYLGTDVEQAADKMIQVALANMYTELSNVMEQHGFDPREFSLMAFGGAGPVTANFLAEEIQAKNVLIPPHPGTLSAL
GALTADFIYDAVCSRQVLLEQIKTAELKVEFMRLQEQAETWLRKQRADMVTEASLLYLLDARYKGQAYEIELPVSPEWLE
GESTSEIADSFHLLHGKQYGHSDGKASIELMNMRVRIIGKTPKPPGGKGCQSNLPEAEPVSQRKIIMKGGTYQASVYRRP
DLRSGQRIDGPAIVEQDDTTTLILPNWSGKTDHAGNLIIERKES

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=736, Percent_Identity=28.3967391304348, Blast_Score=198, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI133901900, Length=719, Percent_Identity=25.0347705146036, Blast_Score=184, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6322634, Length=734, Percent_Identity=29.0190735694823, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI45550492, Length=743, Percent_Identity=27.9946164199192, Blast_Score=217, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.14

Molecular weight: Translated: 74792; Mature: 74792

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEEGYRLGIDIGGTFTDLTLLNPADGSMTAVKTPTVPEDPARGIINGLALLKTRGVQPS
CCCCCEEEEEEECCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHH
EIHHFVHGMTIGLNTLLQRKGADIALFVTEGFRDILSLQRLRLPVPYDFRSRMPEPLIPR
HHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCC
KNVFPIQERMLYDGSEKLPLHMEDIDEAVGQALRKGLKGIVVSFLHSYRNPLHERQAAER
CCCCCHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
IRQIAPELEVATSAELWPQMREYERTVMSVANLYIKPNIHHYFGTLKERLVQEGISAQPF
HHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCCCCE
ITQSNGGLMDIESAAEAPVKTLFSGPAAGVIGSIRTAEAAGEANIITFDVGGTSADISIV
EECCCCCEEECHHHHCCHHHHHHCCCCHHHHHCCHHHHCCCCCEEEEEECCCCCCCEEEE
EKGEPTFTQSNQISGFPIAIPSVAMYSIGAGGGSVAWIDSGGLLKVGPESVGSDPGPACY
ECCCCCCCCCCCCCCCCEECCCCEEEEECCCCCEEEEECCCCEEEECCHHCCCCCCCCCC
GKGTKAALTDAFLICHYLNPNRFAAGNMKLYRERAEKALLPVAEYLGTDVEQAADKMIQV
CCCCHHHHHHHEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ALANMYTELSNVMEQHGFDPREFSLMAFGGAGPVTANFLAEEIQAKNVLIPPHPGTLSAL
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEECCCCCHHHHH
GALTADFIYDAVCSRQVLLEQIKTAELKVEFMRLQEQAETWLRKQRADMVTEASLLYLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
ARYKGQAYEIELPVSPEWLEGESTSEIADSFHLLHGKQYGHSDGKASIELMNMRVRIIGK
CCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEEEC
TPKPPGGKGCQSNLPEAEPVSQRKIIMKGGTYQASVYRRPDLRSGQRIDGPAIVEQDDTT
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCEEEECCCCE
TLILPNWSGKTDHAGNLIIERKES
EEEEECCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MNEEGYRLGIDIGGTFTDLTLLNPADGSMTAVKTPTVPEDPARGIINGLALLKTRGVQPS
CCCCCEEEEEEECCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHH
EIHHFVHGMTIGLNTLLQRKGADIALFVTEGFRDILSLQRLRLPVPYDFRSRMPEPLIPR
HHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCC
KNVFPIQERMLYDGSEKLPLHMEDIDEAVGQALRKGLKGIVVSFLHSYRNPLHERQAAER
CCCCCHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
IRQIAPELEVATSAELWPQMREYERTVMSVANLYIKPNIHHYFGTLKERLVQEGISAQPF
HHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCCCCE
ITQSNGGLMDIESAAEAPVKTLFSGPAAGVIGSIRTAEAAGEANIITFDVGGTSADISIV
EECCCCCEEECHHHHCCHHHHHHCCCCHHHHHCCHHHHCCCCCEEEEEECCCCCCCEEEE
EKGEPTFTQSNQISGFPIAIPSVAMYSIGAGGGSVAWIDSGGLLKVGPESVGSDPGPACY
ECCCCCCCCCCCCCCCCEECCCCEEEEECCCCCEEEEECCCCEEEECCHHCCCCCCCCCC
GKGTKAALTDAFLICHYLNPNRFAAGNMKLYRERAEKALLPVAEYLGTDVEQAADKMIQV
CCCCHHHHHHHEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ALANMYTELSNVMEQHGFDPREFSLMAFGGAGPVTANFLAEEIQAKNVLIPPHPGTLSAL
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEECCCCCHHHHH
GALTADFIYDAVCSRQVLLEQIKTAELKVEFMRLQEQAETWLRKQRADMVTEASLLYLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
ARYKGQAYEIELPVSPEWLEGESTSEIADSFHLLHGKQYGHSDGKASIELMNMRVRIIGK
CCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEEEC
TPKPPGGKGCQSNLPEAEPVSQRKIIMKGGTYQASVYRRPDLRSGQRIDGPAIVEQDDTT
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCEEEECCCCE
TLILPNWSGKTDHAGNLIIERKES
EEEEECCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]