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The map label for this gene is ycbM [H]

Identifier: 52784115

GI number: 52784115

Start: 266794

End: 267723

Strand: Direct

Name: ycbM [H]

Synonym: BLi00292

Alternate gene names: 52784115

Gene position: 266794-267723 (Clockwise)

Preceding gene: 52784114

Following gene: 52784116

Centisome position: 6.32

GC content: 42.9

Gene sequence:

>930_bases
ATGTTATGGATTGGCATTCTGATAATTTTGGCGTCTCTCAATATCGTTCAATATAAAATGAAAAGACAACGGGATCGAAA
CTTGAAGTACATCACGGAAAAGCTCAGTGTGATGCTAAATGAGCATGAGGCTGATCAAATTTTATTAGGAACGGCTGATA
AAGTACTGCGGGCTCTGCTCGTGCAAATTAACCTGTTTGTTGAGGAGCATCAGCACATAACAGCCCGTTTTGCAAAAACG
GAGCAGTCAATGAAACGAATGCTGACCAATATGTCCCATGATCTGAAAACTCCGCTGACCGTCGTGCTCGGGTATATCGA
GGCGATCCAAAATGATTCAGACATGGCGGAAGAGGAGCGTGAAAGACTGCTGGAGAAGCTTTATCAAAAAACAGGCGAAA
TCATTCAGCTGATGAATTCTTTCTTTGACTTGGCCAAGCTGGAATCGGAAGATAAGCAAATACTGCTCACTAAAATACAT
ATCAACGAAATATGCAGAAAAAACATTCTCCAACACTATGATGCCGTTCAGGCAAAAGGTTTTAAAGCTGTCATCGACAT
CCCGGATACCCCGGTTTATGCACATGGAAATGAAGAAGCGCTTGACCGGATTTTGCAAAACCTTTTATCAAATGCGATTC
AATATGGTGCAGACGGAAAGCTGATCGGATTGTCCCTTACATATGATGAGACGTGGATTGTCATTACGGTATGGGACCGT
GGGAAAGGAATTAGTGAGTACGATCAGCAGCGGGTGTTTGAAAGACTGTATACCCTTGAGGAATCGAGAAATAAAGCGTT
CCAGGGAAGCGGGCTCGGTTTAACAATTACAAAAAGGCTCATTGAGAAAATGGGAGGGAACATCTCTCTCCAAAGCAAGC
CGCATGAACGGACAGTGTTTTCCATTACGTTAAAACGAATGACCTATTAG

Upstream 100 bases:

>100_bases
AGGCGCTTGAGAGAAAAGATAGAGGATGATCCTTCCTCCCCGCAATATATTAAAACGCTTTGGGGCATCGGCTATAAATT
AGCAGAGTTTTAGGATGACA

Downstream 100 bases:

>100_bases
CAAACGTAAGAATTTCTTAAGAAACAAGAAATAAAAAAGACAGCGTCCATCGCTACAATAGACACATAGCAGAGACAGGA
AAGGAGAAACAGAGTTGACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MLWIGILIILASLNIVQYKMKRQRDRNLKYITEKLSVMLNEHEADQILLGTADKVLRALLVQINLFVEEHQHITARFAKT
EQSMKRMLTNMSHDLKTPLTVVLGYIEAIQNDSDMAEEERERLLEKLYQKTGEIIQLMNSFFDLAKLESEDKQILLTKIH
INEICRKNILQHYDAVQAKGFKAVIDIPDTPVYAHGNEEALDRILQNLLSNAIQYGADGKLIGLSLTYDETWIVITVWDR
GKGISEYDQQRVFERLYTLEESRNKAFQGSGLGLTITKRLIEKMGGNISLQSKPHERTVFSITLKRMTY

Sequences:

>Translated_309_residues
MLWIGILIILASLNIVQYKMKRQRDRNLKYITEKLSVMLNEHEADQILLGTADKVLRALLVQINLFVEEHQHITARFAKT
EQSMKRMLTNMSHDLKTPLTVVLGYIEAIQNDSDMAEEERERLLEKLYQKTGEIIQLMNSFFDLAKLESEDKQILLTKIH
INEICRKNILQHYDAVQAKGFKAVIDIPDTPVYAHGNEEALDRILQNLLSNAIQYGADGKLIGLSLTYDETWIVITVWDR
GKGISEYDQQRVFERLYTLEESRNKAFQGSGLGLTITKRLIEKMGGNISLQSKPHERTVFSITLKRMTY
>Mature_309_residues
MLWIGILIILASLNIVQYKMKRQRDRNLKYITEKLSVMLNEHEADQILLGTADKVLRALLVQINLFVEEHQHITARFAKT
EQSMKRMLTNMSHDLKTPLTVVLGYIEAIQNDSDMAEEERERLLEKLYQKTGEIIQLMNSFFDLAKLESEDKQILLTKIH
INEICRKNILQHYDAVQAKGFKAVIDIPDTPVYAHGNEEALDRILQNLLSNAIQYGADGKLIGLSLTYDETWIVITVWDR
GKGISEYDQQRVFERLYTLEESRNKAFQGSGLGLTITKRLIEKMGGNISLQSKPHERTVFSITLKRMTY

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=247, Percent_Identity=30.7692307692308, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=28.5714285714286, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1789149, Length=271, Percent_Identity=28.4132841328413, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786912, Length=266, Percent_Identity=27.0676691729323, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=25.6, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87081816, Length=254, Percent_Identity=25.9842519685039, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=25.6637168141593, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790861, Length=216, Percent_Identity=25.462962962963, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994928, Length=226, Percent_Identity=26.9911504424779, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=25.8474576271186, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=25.531914893617, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789403, Length=220, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786783, Length=250, Percent_Identity=23.2, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 35684; Mature: 35684

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWIGILIILASLNIVQYKMKRQRDRNLKYITEKLSVMLNEHEADQILLGTADKVLRALL
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
VQINLFVEEHQHITARFAKTEQSMKRMLTNMSHDLKTPLTVVLGYIEAIQNDSDMAEEER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCCHHHHHHH
ERLLEKLYQKTGEIIQLMNSFFDLAKLESEDKQILLTKIHINEICRKNILQHYDAVQAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
FKAVIDIPDTPVYAHGNEEALDRILQNLLSNAIQYGADGKLIGLSLTYDETWIVITVWDR
CEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEEEECC
GKGISEYDQQRVFERLYTLEESRNKAFQGSGLGLTITKRLIEKMGGNISLQSKPHERTVF
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCEEE
SITLKRMTY
EEEEHHHCC
>Mature Secondary Structure
MLWIGILIILASLNIVQYKMKRQRDRNLKYITEKLSVMLNEHEADQILLGTADKVLRALL
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
VQINLFVEEHQHITARFAKTEQSMKRMLTNMSHDLKTPLTVVLGYIEAIQNDSDMAEEER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCCHHHHHHH
ERLLEKLYQKTGEIIQLMNSFFDLAKLESEDKQILLTKIHINEICRKNILQHYDAVQAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
FKAVIDIPDTPVYAHGNEEALDRILQNLLSNAIQYGADGKLIGLSLTYDETWIVITVWDR
CEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEEEECC
GKGISEYDQQRVFERLYTLEESRNKAFQGSGLGLTITKRLIEKMGGNISLQSKPHERTVF
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCEEE
SITLKRMTY
EEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]