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The map label for this gene is ycbL [H]

Identifier: 52784114

GI number: 52784114

Start: 266181

End: 266786

Strand: Direct

Name: ycbL [H]

Synonym: BLi00291

Alternate gene names: 52784114

Gene position: 266181-266786 (Clockwise)

Preceding gene: 52784113

Following gene: 52784115

Centisome position: 6.3

GC content: 42.24

Gene sequence:

>606_bases
TTGGCTTTTGACGGAGAAGAGGGCGTTCGCTTGTTTCAGCAAGGCAATTATGATGCGATTCTGCTCGACATCATGCTTCC
TAAGCTGAATGGAATGGATTTTCTGAAAATGATCCGTGAACAGAGCAAAGTTCCGGTTTTAATGATTTCCGCAAAAGACG
GGGATGTCGATAAAGCGCTGGGGCTGGGCTTTGGTGCGGATGATTATATTGCCAAGCCGTTTTCGATGATCGAACTGACC
GCAAGAATAAAAGCCGCCATTCGGCGGGCAACGCAATATTCCGTCAGTGAACCGGCAAATCAAAAAATATTACGTGTTCA
CGAGCTTACGGTTGATATAGAAAATGTATCCGTACAAAAAAATGGTGAACCGCTTCAGCTGACATCGACGGAATGGAAAA
TGCTGACTTTGTTTGTGACAAACCCTAAAAAAGTGTTTACAAAAGAACAAATCTATCGTTCGGTTTGGAATGATGATTAT
TTTGGCGATCAAAATATTATTAACGTTCATATGAGGCGCTTGAGAGAAAAGATAGAGGATGATCCTTCCTCCCCGCAATA
TATTAAAACGCTTTGGGGCATCGGCTATAAATTAGCAGAGTTTTAG

Upstream 100 bases:

>100_bases
TGGGTGAACAAGATGCAGCACATATTGCTTATTGAAGATGATCATTCGATCAGTGAAATGGTCGATCATTATTTAACAAA
AGAAGGATTTGAGGTCGTGC

Downstream 100 bases:

>100_bases
GATGACAATGTTATGGATTGGCATTCTGATAATTTTGGCGTCTCTCAATATCGTTCAATATAAAATGAAAAGACAACGGG
ATCGAAACTTGAAGTACATC

Product: YcbL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MAFDGEEGVRLFQQGNYDAILLDIMLPKLNGMDFLKMIREQSKVPVLMISAKDGDVDKALGLGFGADDYIAKPFSMIELT
ARIKAAIRRATQYSVSEPANQKILRVHELTVDIENVSVQKNGEPLQLTSTEWKMLTLFVTNPKKVFTKEQIYRSVWNDDY
FGDQNIINVHMRRLREKIEDDPSSPQYIKTLWGIGYKLAEF

Sequences:

>Translated_201_residues
MAFDGEEGVRLFQQGNYDAILLDIMLPKLNGMDFLKMIREQSKVPVLMISAKDGDVDKALGLGFGADDYIAKPFSMIELT
ARIKAAIRRATQYSVSEPANQKILRVHELTVDIENVSVQKNGEPLQLTSTEWKMLTLFVTNPKKVFTKEQIYRSVWNDDY
FGDQNIINVHMRRLREKIEDDPSSPQYIKTLWGIGYKLAEF
>Mature_200_residues
AFDGEEGVRLFQQGNYDAILLDIMLPKLNGMDFLKMIREQSKVPVLMISAKDGDVDKALGLGFGADDYIAKPFSMIELTA
RIKAAIRRATQYSVSEPANQKILRVHELTVDIENVSVQKNGEPLQLTSTEWKMLTLFVTNPKKVFTKEQIYRSVWNDDYF
GDQNIINVHMRRLREKIEDDPSSPQYIKTLWGIGYKLAEF

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=185, Percent_Identity=37.2972972972973, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789809, Length=195, Percent_Identity=32.8205128205128, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786911, Length=181, Percent_Identity=34.2541436464088, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1786784, Length=199, Percent_Identity=36.1809045226131, Blast_Score=131, Evalue=2e-32,
Organism=Escherichia coli, GI87082012, Length=195, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=9e-29,
Organism=Escherichia coli, GI1788394, Length=193, Percent_Identity=32.1243523316062, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789402, Length=197, Percent_Identity=34.010152284264, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1787229, Length=195, Percent_Identity=32.8205128205128, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1790863, Length=201, Percent_Identity=30.3482587064677, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI2367329, Length=176, Percent_Identity=34.6590909090909, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1790552, Length=188, Percent_Identity=35.1063829787234, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1790860, Length=182, Percent_Identity=30.7692307692308, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1787375, Length=197, Percent_Identity=28.4263959390863, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI145693140, Length=203, Percent_Identity=26.6009852216749, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 23038; Mature: 22907

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDGEEGVRLFQQGNYDAILLDIMLPKLNGMDFLKMIREQSKVPVLMISAKDGDVDKAL
CCCCCCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHH
GLGFGADDYIAKPFSMIELTARIKAAIRRATQYSVSEPANQKILRVHELTVDIENVSVQK
HCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEEEEEEEEEEEEC
NGEPLQLTSTEWKMLTLFVTNPKKVFTKEQIYRSVWNDDYFGDQNIINVHMRRLREKIED
CCCCEEEECCCEEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
DPSSPQYIKTLWGIGYKLAEF
CCCCHHHHHHHHHCCHHHHCC
>Mature Secondary Structure 
AFDGEEGVRLFQQGNYDAILLDIMLPKLNGMDFLKMIREQSKVPVLMISAKDGDVDKAL
CCCCCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHH
GLGFGADDYIAKPFSMIELTARIKAAIRRATQYSVSEPANQKILRVHELTVDIENVSVQK
HCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEEEEEEEEEEEEC
NGEPLQLTSTEWKMLTLFVTNPKKVFTKEQIYRSVWNDDYFGDQNIINVHMRRLREKIED
CCCCEEEECCCEEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
DPSSPQYIKTLWGIGYKLAEF
CCCCHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]