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The map label for this gene is ycbH [H]

Identifier: 52784112

GI number: 52784112

Start: 264404

End: 265930

Strand: Direct

Name: ycbH [H]

Synonym: BLi00289

Alternate gene names: 52784112

Gene position: 264404-265930 (Clockwise)

Preceding gene: 52784111

Following gene: 52784113

Centisome position: 6.26

GC content: 53.5

Gene sequence:

>1527_bases
ATGCTTGTCAATCAAACTGAAACCCCGTTGTACATTAAGGTGAACGAAAAAGACAATGCCGCAATCATCGCCAATGCCGG
CGGACTGCCGCAAGGGACGGTGTTTCCTTGCGGGCTTAAGCTGCAAGAGCGGATTCCTCAAGGGCATAAAGTGGCTTTAA
CAGACATCACACAGGGCGGTGCCGTTATTCGCTACGGCGAAATTATCGGCTATGCCGTCAAACCGATCGAAAAAGGCGGG
TGGATTTCCGAGTCGCATATCATGCTTCCGGAAGCTCCGCCGCTCGATGAACTGCCCATCGCCAACAAAGTTCCAAAACC
CGCTCCCCTTCTTGAGGGGTATACATTTGAAGGATACCGGAATGAAGACGGGAGCGTCGGCACGAGAAACGTGCTTGGCA
TTATGACAAGCGTTCAATGCGTCGCAGGCGTTCTCGATTACGCAGTGAAACGAATTAAAGAGGAACTGCTCCCAAAATAT
CCGAACGTTGACGGTGTCGCTGCATTAAATCATCAGTACGGCTGCGGCGTGGCGATTAATGCGCCGGAAGCCAAAATCCC
GATCCGAACGATTCAAAATATCGCCAGGCACCCTAATTTCGGCGGTGAAGCGATGGTGATCGGACTCGGCTGCGAGAAGC
TCCTTCCGACGAAGATAGAGCCGGAAGGAGACGCTGAAAACATTCTTTCACTGCAGGAACGGCAAGGGTTTCAGCAAATG
ATACAATCGATTATGGAAATGGCCGAAGAGCGCTTAAAAAGGCTGAATGAACGGAAGCGGATGACATGTCCCGCTTCAGA
CCTGGTGATCGGCCTACAGTGCGGAGGCAGCGACGCCTTTTCAGGAGTGACCGCAAACCCTGCGTCCGGATATGCGGCCG
ACTTACTTGTCCGGGCAGGGGCCACGGTTTTATTTTCGGAAGTCACCGAAGTCCGCGATGCCGTTCATCTCCTAACACCG
CGCGCTGTCAATGAAGAAGTCGGCCGCGCCCTGATTCGGGAAATGGCTTGGTATGACCGCTATCTGGAAAGAGGCGAATC
AGACCGAAGCGCCAATCCGTCGCCGGGAAACAAAAAAGGCGGACTGGCAAACGTGGTCGAGAAATCGCTCGGGTCGATCG
CGAAGTCGGGAAGCAGCCCGATCAGTGCCGTACTTGCGCCCGGTGAAAGGGCTGTACAGAAAGGACTCATTTTTGCGGCG
ACACCTGCAAGCGATTTTGTATGCGGCACCCTGCAATTGGCTTCTGGCATGCATTTGCAGGTATTTACAACCGGAAGGGG
AACGCCGTACGGCCTTGAAATGGCTCCGGTTTTGAAAGTGGCGACCCGGCAGTCATTATCAGAAGATTGGCACGACTTGA
TCGACGTCAATGCCGGAAGGATCGCTACAGGCGAAGCTTCAATAGAGGAAGTCGGCTGGGAAATCTTCCGGACGATACTT
GACGTCGCAAGCGGAAGGAAAACATGGGCGGAACATTGGGGACTCTCCAATGACTTGTGTTTATTCAACCCAGCGCCTGT
GACTTGA

Upstream 100 bases:

>100_bases
AACAATCATTAAGTTGTTTGACAGCGCTTTCTAACATGTGCCGCGGCGGGAGAAGGGCCGCGGAAAGGCGCTGATCGAAA
AGGGGAGTTGATCAATCCTT

Downstream 100 bases:

>100_bases
TCCGTGCTAGTGGGAAAGTAGATTGGTATCGGCCAAAAGATCCGGAGATACAATAGGTTTCAACTAGAAATATGGATAAT
TTTTGTAAAAAACACACGTT

Product: YcbH

Products: NA

Alternate protein names: GalcD [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MLVNQTETPLYIKVNEKDNAAIIANAGGLPQGTVFPCGLKLQERIPQGHKVALTDITQGGAVIRYGEIIGYAVKPIEKGG
WISESHIMLPEAPPLDELPIANKVPKPAPLLEGYTFEGYRNEDGSVGTRNVLGIMTSVQCVAGVLDYAVKRIKEELLPKY
PNVDGVAALNHQYGCGVAINAPEAKIPIRTIQNIARHPNFGGEAMVIGLGCEKLLPTKIEPEGDAENILSLQERQGFQQM
IQSIMEMAEERLKRLNERKRMTCPASDLVIGLQCGGSDAFSGVTANPASGYAADLLVRAGATVLFSEVTEVRDAVHLLTP
RAVNEEVGRALIREMAWYDRYLERGESDRSANPSPGNKKGGLANVVEKSLGSIAKSGSSPISAVLAPGERAVQKGLIFAA
TPASDFVCGTLQLASGMHLQVFTTGRGTPYGLEMAPVLKVATRQSLSEDWHDLIDVNAGRIATGEASIEEVGWEIFRTIL
DVASGRKTWAEHWGLSNDLCLFNPAPVT

Sequences:

>Translated_508_residues
MLVNQTETPLYIKVNEKDNAAIIANAGGLPQGTVFPCGLKLQERIPQGHKVALTDITQGGAVIRYGEIIGYAVKPIEKGG
WISESHIMLPEAPPLDELPIANKVPKPAPLLEGYTFEGYRNEDGSVGTRNVLGIMTSVQCVAGVLDYAVKRIKEELLPKY
PNVDGVAALNHQYGCGVAINAPEAKIPIRTIQNIARHPNFGGEAMVIGLGCEKLLPTKIEPEGDAENILSLQERQGFQQM
IQSIMEMAEERLKRLNERKRMTCPASDLVIGLQCGGSDAFSGVTANPASGYAADLLVRAGATVLFSEVTEVRDAVHLLTP
RAVNEEVGRALIREMAWYDRYLERGESDRSANPSPGNKKGGLANVVEKSLGSIAKSGSSPISAVLAPGERAVQKGLIFAA
TPASDFVCGTLQLASGMHLQVFTTGRGTPYGLEMAPVLKVATRQSLSEDWHDLIDVNAGRIATGEASIEEVGWEIFRTIL
DVASGRKTWAEHWGLSNDLCLFNPAPVT
>Mature_508_residues
MLVNQTETPLYIKVNEKDNAAIIANAGGLPQGTVFPCGLKLQERIPQGHKVALTDITQGGAVIRYGEIIGYAVKPIEKGG
WISESHIMLPEAPPLDELPIANKVPKPAPLLEGYTFEGYRNEDGSVGTRNVLGIMTSVQCVAGVLDYAVKRIKEELLPKY
PNVDGVAALNHQYGCGVAINAPEAKIPIRTIQNIARHPNFGGEAMVIGLGCEKLLPTKIEPEGDAENILSLQERQGFQQM
IQSIMEMAEERLKRLNERKRMTCPASDLVIGLQCGGSDAFSGVTANPASGYAADLLVRAGATVLFSEVTEVRDAVHLLTP
RAVNEEVGRALIREMAWYDRYLERGESDRSANPSPGNKKGGLANVVEKSLGSIAKSGSSPISAVLAPGERAVQKGLIFAA
TPASDFVCGTLQLASGMHLQVFTTGRGTPYGLEMAPVLKVATRQSLSEDWHDLIDVNAGRIATGEASIEEVGWEIFRTIL
DVASGRKTWAEHWGLSNDLCLFNPAPVT

Specific function: D-galactarate metabolism; first step. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789516, Length=515, Percent_Identity=67.5728155339806, Blast_Score=719, Evalue=0.0,
Organism=Escherichia coli, GI1789475, Length=496, Percent_Identity=33.8709677419355, Blast_Score=235, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR017654
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.42 [H]

Molecular weight: Translated: 54612; Mature: 54612

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVNQTETPLYIKVNEKDNAAIIANAGGLPQGTVFPCGLKLQERIPQGHKVALTDITQGG
CCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCEECCCCHHHHHCCCCCEEEEEEECCCC
AVIRYGEIIGYAVKPIEKGGWISESHIMLPEAPPLDELPIANKVPKPAPLLEGYTFEGYR
CEEEEHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEECCEE
NEDGSVGTRNVLGIMTSVQCVAGVLDYAVKRIKEELLPKYPNVDGVAALNHQYGCGVAIN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEC
APEAKIPIRTIQNIARHPNFGGEAMVIGLGCEKLLPTKIEPEGDAENILSLQERQGFQQM
CCCCCCCHHHHHHHHHCCCCCCCEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
IQSIMEMAEERLKRLNERKRMTCPASDLVIGLQCGGSDAFSGVTANPASGYAADLLVRAG
HHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCC
ATVLFSEVTEVRDAVHLLTPRAVNEEVGRALIREMAWYDRYLERGESDRSANPSPGNKKG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GLANVVEKSLGSIAKSGSSPISAVLAPGERAVQKGLIFAATPASDFVCGTLQLASGMHLQ
CHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCEEEEECCCCCHHHHHHHHCCCCEEE
VFTTGRGTPYGLEMAPVLKVATRQSLSEDWHDLIDVNAGRIATGEASIEEVGWEIFRTIL
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHH
DVASGRKTWAEHWGLSNDLCLFNPAPVT
HHHCCCHHHHHHCCCCCCEEECCCCCCC
>Mature Secondary Structure
MLVNQTETPLYIKVNEKDNAAIIANAGGLPQGTVFPCGLKLQERIPQGHKVALTDITQGG
CCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCEECCCCHHHHHCCCCCEEEEEEECCCC
AVIRYGEIIGYAVKPIEKGGWISESHIMLPEAPPLDELPIANKVPKPAPLLEGYTFEGYR
CEEEEHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEECCEE
NEDGSVGTRNVLGIMTSVQCVAGVLDYAVKRIKEELLPKYPNVDGVAALNHQYGCGVAIN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEC
APEAKIPIRTIQNIARHPNFGGEAMVIGLGCEKLLPTKIEPEGDAENILSLQERQGFQQM
CCCCCCCHHHHHHHHHCCCCCCCEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
IQSIMEMAEERLKRLNERKRMTCPASDLVIGLQCGGSDAFSGVTANPASGYAADLLVRAG
HHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCC
ATVLFSEVTEVRDAVHLLTPRAVNEEVGRALIREMAWYDRYLERGESDRSANPSPGNKKG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GLANVVEKSLGSIAKSGSSPISAVLAPGERAVQKGLIFAATPASDFVCGTLQLASGMHLQ
CHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCEEEEECCCCCHHHHHHHHCCCCEEE
VFTTGRGTPYGLEMAPVLKVATRQSLSEDWHDLIDVNAGRIATGEASIEEVGWEIFRTIL
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHH
DVASGRKTWAEHWGLSNDLCLFNPAPVT
HHHCCCHHHHHHCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]