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The map label for this gene is yrkA2 [H]

Identifier: 52784065

GI number: 52784065

Start: 216687

End: 217076

Strand: Direct

Name: yrkA2 [H]

Synonym: BLi00239

Alternate gene names: 52784065

Gene position: 216687-217076 (Clockwise)

Preceding gene: 52784064

Following gene: 52784066

Centisome position: 5.13

GC content: 35.13

Gene sequence:

>390_bases
ATGCAAAAAGAGCGAATTCACATTGCTATCTTATTGGATGAGTATGGAGGTACGTCGGGTTTAGTAACAGTTGAAGATAT
CCTTGAAGAAATCGTGGGAGAAATTAGAGATGAATTTGATGTTGATGAAATTCCGGATATTCGAAAGTTAAAGGATGGTC
ACTTTATAATAAACTCAAAGCTGCTAATTGAAGATGTCAACGATCTTTTGGATATCAATTTATCTCATGAGGAAGTGGAC
ACAATAGGCGGCTGGTTCATGACTCAAAACATGGATGCAGAAGCTGGTTCTGAACTAGAAGCTGATGGTTATATTTTTAA
AGTGCAAAAAATAGATGGGCGGCAGATTCATTTTCTTGAAGTTAAAAGAGAAAAAAATTCAAATCAATAA

Upstream 100 bases:

>100_bases
CTGGAAAGCTGAAAATCGGCGAGTTGGCGGAAGGAACTAAGGTAACGAAGAGAACAATTGATTATTATACAAAGCTGGGT
TTGTTAATCTGCTGACGAAA

Downstream 100 bases:

>100_bases
TGATTTAAAAAAAGAGAGCCTGAAACTTTTCAGGTTCTTTTTATTATGGAATACAACCATTGACCAATGACAAGTCGAAT
AGCCGATGCTGACAAGTACC

Product: YrkA2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MQKERIHIAILLDEYGGTSGLVTVEDILEEIVGEIRDEFDVDEIPDIRKLKDGHFIINSKLLIEDVNDLLDINLSHEEVD
TIGGWFMTQNMDAEAGSELEADGYIFKVQKIDGRQIHFLEVKREKNSNQ

Sequences:

>Translated_129_residues
MQKERIHIAILLDEYGGTSGLVTVEDILEEIVGEIRDEFDVDEIPDIRKLKDGHFIINSKLLIEDVNDLLDINLSHEEVD
TIGGWFMTQNMDAEAGSELEADGYIFKVQKIDGRQIHFLEVKREKNSNQ
>Mature_129_residues
MQKERIHIAILLDEYGGTSGLVTVEDILEEIVGEIRDEFDVDEIPDIRKLKDGHFIINSKLLIEDVNDLLDINLSHEEVD
TIGGWFMTQNMDAEAGSELEADGYIFKVQKIDGRQIHFLEVKREKNSNQ

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=95, Percent_Identity=51.5789473684211, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1786879, Length=129, Percent_Identity=44.9612403100775, Blast_Score=83, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 14771; Mature: 14771

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKERIHIAILLDEYGGTSGLVTVEDILEEIVGEIRDEFDVDEIPDIRKLKDGHFIINSK
CCCCEEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCEEEECE
LLIEDVNDLLDINLSHEEVDTIGGWFMTQNMDAEAGSELEADGYIFKVQKIDGRQIHFLE
EEEECCHHHHCCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEE
VKREKNSNQ
EECCCCCCC
>Mature Secondary Structure
MQKERIHIAILLDEYGGTSGLVTVEDILEEIVGEIRDEFDVDEIPDIRKLKDGHFIINSK
CCCCEEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCEEEECE
LLIEDVNDLLDINLSHEEVDTIGGWFMTQNMDAEAGSELEADGYIFKVQKIDGRQIHFLE
EEEECCHHHHCCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEE
VKREKNSNQ
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377; 8969508; 7608059 [H]