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The map label for this gene is norA [H]

Identifier: 52144540

GI number: 52144540

Start: 786097

End: 787617

Strand: Reverse

Name: norA [H]

Synonym: BCZK0684

Alternate gene names: 52144540

Gene position: 787617-786097 (Counterclockwise)

Preceding gene: 52144532

Following gene: 52144541

Centisome position: 14.86

GC content: 36.95

Gene sequence:

>1521_bases
ATGTACACGCCTCTTTCTTCATCATATTGTAAACCTTTTCAAATATATGTAGTGAAAAAGTATATATCCCCTTCTCATTC
ACTACTTTTTGAATCCGCTTTCTTTAAAGAAAAAACAATTTCTATCATTCATAACAACTACCAGTCTATACATCTATACT
TTACATCTTTTTTTCATAGTTGTGTAGTCTTTCCACAAATTTGTCAGTTTTTTACCTCGAAAATTGTTGTACGTTTTCAA
GGCACCTTCCTTGACTGTTTCATTGGCCAATACATATACTCGAAAGAAAAGAGAAATTTTTATATAGGGGATGAATATAT
GGGAGAAGCAATACTCGTAAAACGAGAACCGTTATGGACAAAAGAATTTTTCGCGCTAATTCTAGCAAACTTATGTATGT
TCTTAGGATTTCAAATGTTAATTCCGACTTTACCTGTTTATGTGAAAGAAATTGGAGGTACAAGTTCCAATATTGGATTT
GTTGTCGGTATGTTTACTGTTGCGGCACTTTTTGTTAGACCGCTAACTGGAAATGCCTTGCAAAAATTCAGCAAAAAAAT
CATTTTAATGATTGGCACTGCTATTTGTTTACTCGCTATGGGTAGTTATCTTTTCGCTTCAACGGTTTTCCTATTGCTTG
CCGTTCGAATTTTACACGGAGCCGGTTTTGGTATTACAACGACTACATATGGAACTGTCGTTTCCGATTTAATTCCGCAA
GCTCGCCGCGGTGAGGGCATGGGATATTTCGGCCTTTCTGGAACGATTGCAATGGCGCTCGGCCCACTTATCGGACTTTG
GCTTATGCAAACATATAACTTCACGATTCTTTTTTTATGTGCACTTTCCTGTACAATTGTTTCATTAATATTAACGAAAC
TACTTCAAATTAAAAAATCACCACAACCACCAAAGCAAATATCTGGTACCTTTCTCGATGGATTTATTGAGCGCAAAGCT
TTACTTCCTTCATTATTAATATTATGTATTACATTAATGTACGGGGGAATCGGAAGCTTTATTACGTTATTTGCTACGGA
AGTCGGCATTGCTGATATAAGCCTCTTCTTCTTATTTAATGCACTTGCAATCGCTGTTACTCGTCCATTTTCCGGAAAGC
TATATGATGCGAAAGGTCATTCATTCGTAATTATTCCAGGAGTTATTATTACGTTTGCAGGGATTATTTTATTATCGTAT
ACAACTACCATTCCAAGCTTAATTATTGCAGCAGCATGCTACGGAAGTGGTTTCGGAGCGATTCAACCTGCACTACAAGC
GTGGATGATTGACCGAGTAGCACCGCACCGACGAGGAGTCGCAACAGCTACATTCTTCTCAGCATTTGACCTTGGAATTG
GTGCTGGCGCGATTATTTTTGGATTCATTGCACATTTTACAAACTACGCAACTGTATATCGTTATTCCTCTCTACTACTT
ATTGCTTTCCTGTTCATTTACATTACAAGTGTAAAAAAACAAAAGCATGGTGATAAAAATACGGAAAAAGCTGCTGGATA
A

Upstream 100 bases:

>100_bases
ATACACGATTAAATCCATATTTACTTGCTAATGTTAAATACTCTTTATCTTTCTCTACTGTTGAATGTTCTGGATAAATA
GAAATACCTAATCGTCTCAT

Downstream 100 bases:

>100_bases
TTCCAGTGGCTTTTTTACGTATTTTTGATTTTATAAAACTACATGCATTTTCCTACATATTTTTTTACCTTTCATCAAAA
AATATACGATGAACTCACAG

Product: quinolone resistence protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MYTPLSSSYCKPFQIYVVKKYISPSHSLLFESAFFKEKTISIIHNNYQSIHLYFTSFFHSCVVFPQICQFFTSKIVVRFQ
GTFLDCFIGQYIYSKEKRNFYIGDEYMGEAILVKREPLWTKEFFALILANLCMFLGFQMLIPTLPVYVKEIGGTSSNIGF
VVGMFTVAALFVRPLTGNALQKFSKKIILMIGTAICLLAMGSYLFASTVFLLLAVRILHGAGFGITTTTYGTVVSDLIPQ
ARRGEGMGYFGLSGTIAMALGPLIGLWLMQTYNFTILFLCALSCTIVSLILTKLLQIKKSPQPPKQISGTFLDGFIERKA
LLPSLLILCITLMYGGIGSFITLFATEVGIADISLFFLFNALAIAVTRPFSGKLYDAKGHSFVIIPGVIITFAGIILLSY
TTTIPSLIIAAACYGSGFGAIQPALQAWMIDRVAPHRRGVATATFFSAFDLGIGAGAIIFGFIAHFTNYATVYRYSSLLL
IAFLFIYITSVKKQKHGDKNTEKAAG

Sequences:

>Translated_506_residues
MYTPLSSSYCKPFQIYVVKKYISPSHSLLFESAFFKEKTISIIHNNYQSIHLYFTSFFHSCVVFPQICQFFTSKIVVRFQ
GTFLDCFIGQYIYSKEKRNFYIGDEYMGEAILVKREPLWTKEFFALILANLCMFLGFQMLIPTLPVYVKEIGGTSSNIGF
VVGMFTVAALFVRPLTGNALQKFSKKIILMIGTAICLLAMGSYLFASTVFLLLAVRILHGAGFGITTTTYGTVVSDLIPQ
ARRGEGMGYFGLSGTIAMALGPLIGLWLMQTYNFTILFLCALSCTIVSLILTKLLQIKKSPQPPKQISGTFLDGFIERKA
LLPSLLILCITLMYGGIGSFITLFATEVGIADISLFFLFNALAIAVTRPFSGKLYDAKGHSFVIIPGVIITFAGIILLSY
TTTIPSLIIAAACYGSGFGAIQPALQAWMIDRVAPHRRGVATATFFSAFDLGIGAGAIIFGFIAHFTNYATVYRYSSLLL
IAFLFIYITSVKKQKHGDKNTEKAAG
>Mature_506_residues
MYTPLSSSYCKPFQIYVVKKYISPSHSLLFESAFFKEKTISIIHNNYQSIHLYFTSFFHSCVVFPQICQFFTSKIVVRFQ
GTFLDCFIGQYIYSKEKRNFYIGDEYMGEAILVKREPLWTKEFFALILANLCMFLGFQMLIPTLPVYVKEIGGTSSNIGF
VVGMFTVAALFVRPLTGNALQKFSKKIILMIGTAICLLAMGSYLFASTVFLLLAVRILHGAGFGITTTTYGTVVSDLIPQ
ARRGEGMGYFGLSGTIAMALGPLIGLWLMQTYNFTILFLCALSCTIVSLILTKLLQIKKSPQPPKQISGTFLDGFIERKA
LLPSLLILCITLMYGGIGSFITLFATEVGIADISLFFLFNALAIAVTRPFSGKLYDAKGHSFVIIPGVIITFAGIILLSY
TTTIPSLIIAAACYGSGFGAIQPALQAWMIDRVAPHRRGVATATFFSAFDLGIGAGAIIFGFIAHFTNYATVYRYSSLLL
IAFLFIYITSVKKQKHGDKNTEKAAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 55793; Mature: 55793

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00359 RIBOSOMAL_L11 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTPLSSSYCKPFQIYVVKKYISPSHSLLFESAFFKEKTISIIHNNYQSIHLYFTSFFHS
CCCCCCCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
CVVFPQICQFFTSKIVVRFQGTFLDCFIGQYIYSKEKRNFYIGDEYMGEAILVKREPLWT
HHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHCCCCEEECHHHCCCEEEEECCCCHH
KEFFALILANLCMFLGFQMLIPTLPVYVKEIGGTSSNIGFVVGMFTVAALFVRPLTGNAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
QKFSKKIILMIGTAICLLAMGSYLFASTVFLLLAVRILHGAGFGITTTTYGTVVSDLIPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCH
ARRGEGMGYFGLSGTIAMALGPLIGLWLMQTYNFTILFLCALSCTIVSLILTKLLQIKKS
HHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQPPKQISGTFLDGFIERKALLPSLLILCITLMYGGIGSFITLFATEVGIADISLFFLFN
CCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ALAIAVTRPFSGKLYDAKGHSFVIIPGVIITFAGIILLSYTTTIPSLIIAAACYGSGFGA
HHHHHHCCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IQPALQAWMIDRVAPHRRGVATATFFSAFDLGIGAGAIIFGFIAHFTNYATVYRYSSLLL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFLFIYITSVKKQKHGDKNTEKAAG
HHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MYTPLSSSYCKPFQIYVVKKYISPSHSLLFESAFFKEKTISIIHNNYQSIHLYFTSFFHS
CCCCCCCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
CVVFPQICQFFTSKIVVRFQGTFLDCFIGQYIYSKEKRNFYIGDEYMGEAILVKREPLWT
HHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHCCCCEEECHHHCCCEEEEECCCCHH
KEFFALILANLCMFLGFQMLIPTLPVYVKEIGGTSSNIGFVVGMFTVAALFVRPLTGNAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
QKFSKKIILMIGTAICLLAMGSYLFASTVFLLLAVRILHGAGFGITTTTYGTVVSDLIPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCH
ARRGEGMGYFGLSGTIAMALGPLIGLWLMQTYNFTILFLCALSCTIVSLILTKLLQIKKS
HHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQPPKQISGTFLDGFIERKALLPSLLILCITLMYGGIGSFITLFATEVGIADISLFFLFN
CCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ALAIAVTRPFSGKLYDAKGHSFVIIPGVIITFAGIILLSYTTTIPSLIIAAACYGSGFGA
HHHHHHCCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IQPALQAWMIDRVAPHRRGVATATFFSAFDLGIGAGAIIFGFIAHFTNYATVYRYSSLLL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFLFIYITSVKKQKHGDKNTEKAAG
HHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]