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The map label for this gene is alkA

Identifier: 52144451

GI number: 52144451

Start: 880675

End: 881292

Strand: Reverse

Name: alkA

Synonym: BCZK0774

Alternate gene names: NA

Gene position: 881292-880675 (Counterclockwise)

Preceding gene: 52144447

Following gene: 52144453

Centisome position: 16.63

GC content: 41.42

Gene sequence:

>618_bases
ATGCAGGCACCTCCTTCCTTTTATGAAGGCGATACGTTAGAAGTCGCAAAAAAATTACTCGGACAGAAACTTGTTCATAT
TGTAGATGGAATAAAGCGAAGTGGAATCATTGTTGAAGTAGAAGCATACAAAGGTCCCGATGATAAGGCCGCACATAGTT
ACGGCGGCAGACGGACGGATCGTACGGAAGTCATGTTTGGTGCGCCAGGACATGCTTACGTATATTTAATTTACGGTATG
TACCATTGTTTTAACGTCATTACAGCACCAGTAGGCACCCCGCAAGGTGTTCTCATTCGAGCCCTTGAGCCGGTAGATGG
AATAGAAGAAATAAAACTAGCGCGCTACAACAAAACAGACATTACAAAAGCGCAGTATAAAAACTTAACGAACGGACCAG
GAAAATTATGTCGTGCCCTTGGAATCACTTTAGAAGAACGAGGCGTATCATTACAAAGTGACACATTGCATATTGAACTC
GTCCCAGAAGAAGAACACATATCATCACAATATAAAATAACAGCAGGTCCTCGTATTAATATCGATTATGCAGAAGAAGC
TGTACATTATCCGTGGCGTTTTTATTATGAGGGACATCCGTTTGTTTCAAAGAAATGA

Upstream 100 bases:

>100_bases
CATAATTTATGAAATAAATGTAGCAAATAGAACGAGTTAGAATTTCTACTGAAAATTTGGTTTACTATATACATATACAC
TCAGTAAAGGAGATAGTACA

Downstream 100 bases:

>100_bases
ACGATATCAACGATTTTTCGAATATATCTATCGTAACTTACAATATATCAACGATTTTTCAAATATATCTATCATAACTC
AAAATATATCAACGATTCGA

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPDDKAAHSYGGRRTDRTEVMFGAPGHAYVYLIYGM
YHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTDITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIEL
VPEEEHISSQYKITAGPRINIDYAEEAVHYPWRFYYEGHPFVSKK

Sequences:

>Translated_205_residues
MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPDDKAAHSYGGRRTDRTEVMFGAPGHAYVYLIYGM
YHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTDITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIEL
VPEEEHISSQYKITAGPRINIDYAEEAVHYPWRFYYEGHPFVSKK
>Mature_205_residues
MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPDDKAAHSYGGRRTDRTEVMFGAPGHAYVYLIYGM
YHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTDITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIEL
VPEEEHISSQYKITAGPRINIDYAEEAVHYPWRFYYEGHPFVSKK

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family [H]

Homologues:

Organism=Homo sapiens, GI62632769, Length=203, Percent_Identity=39.4088669950739, Blast_Score=127, Evalue=5e-30,
Organism=Homo sapiens, GI62632765, Length=203, Percent_Identity=39.4088669950739, Blast_Score=127, Evalue=5e-30,
Organism=Homo sapiens, GI62632771, Length=203, Percent_Identity=39.4088669950739, Blast_Score=127, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011034
- InterPro:   IPR003180 [H]

Pfam domain/function: PF02245 Pur_DNA_glyco [H]

EC number: 3.2.2.21

Molecular weight: Translated: 22967; Mature: 22967

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPDDKAAHSYGGRRTD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCEEEEEECCCCCCCHHHHHCCCCCCC
RTEVMFGAPGHAYVYLIYGMYHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTD
CCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCC
ITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIELVPEEEHISSQYKITAGPRIN
CCHHHHCCCCCCHHHHHHHHCCEEHHCCCEEECCEEEEEEECCHHHCCCEEEEECCCEEE
IDYAEEAVHYPWRFYYEGHPFVSKK
EEHHHHHHCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPDDKAAHSYGGRRTD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCEEEEEECCCCCCCHHHHHCCCCCCC
RTEVMFGAPGHAYVYLIYGMYHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTD
CCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCC
ITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIELVPEEEHISSQYKITAGPRIN
CCHHHHCCCCCCHHHHHHHHCCEEHHCCCEEECCEEEEEEECCHHHCCCEEEEECCCEEE
IDYAEEAVHYPWRFYYEGHPFVSKK
EEHHHHHHCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA