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The map label for this gene is clpB [H]

Identifier: 52144162

GI number: 52144162

Start: 1173390

End: 1175990

Strand: Direct

Name: clpB [H]

Synonym: BCZK1066

Alternate gene names: 52144162

Gene position: 1173390-1175990 (Clockwise)

Preceding gene: 52144161

Following gene: 52144160

Centisome position: 22.14

GC content: 39.1

Gene sequence:

>2601_bases
ATGGACTTAAATCAAATGACAACAAAAACACAAGAGGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCACCATCA
AGAAGTAGATACTGTTCATCTCTTGTTTACATTATTAGAAGAGCAAGATGGGCTAGCAGTACGTATTTTTCAAAAAATGA
ATGTCGATATAGAAGCATTAAAACAAGGCGTAGAAAATTTAATTAAGAAAAAGCCTTCCGTAACGGGAAGCGGTGCAGAA
GCAGGTAAATTATATATAACAGGTGCCCTGCAACAACTGCTAGTAAGAGCAGGAAAAGAAGCAGAGAAATTGCAAGATGA
TTACATTTCAGTGGAACATGTATTACTTGCTTTTACTGAAGAAAAAGGAGATATAAGCCAATTATTTACAAGATTTCATA
TTACGAAAGACAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGTCGTGATTTAGTGGCGGAAGTGAAAGCAGGGAAAATTGATCCTGTTATCGGCCGCGA
TAGTGAAATTCGCCGCGTAATCCGCATTCTTTCACGTAAAACGAAAAACAACCCTGTTTTAATTGGTGAGCCAGGTGTTG
GTAAAACAGCAATCGTTGAAGGGTTAGCACAGCGTATTGTGAAGAAGGATGTACCTGAAGGATTAAAAGATAGAACAATC
TTTGCGTTAGATATGAGTGCGCTTGTAGCTGGTGCGAAATTCCGCGGTGAGTTCGAAGAGCGTTTGCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGTCGCATTTTACTATTCATTGATGAACTTCACACAATCGTCGGCGCTGGAAAAACAGAAG
GTGCGATGGATGCAGGGAATATGTTAAAACCGATGCTTGCGCGTGGTGAACTGCATTGTATCGGGGCGACAACACTAGAT
GAATATCGTAAATATATTGAGAAAGATCCAGCACTAGAAAGACGTTTCCAACAAGTATTAGCAGAAGAACCAACTGTTGA
AGATACAATTTCTATTTTACGTGGTTTAAAAGAGCGTTTTGAAATTTATCACGGTGTAAATATTCATGACCGCGCAATTG
TAGCAGCATCAGTTTTATCAGATCGATATATTTCAGATCGTTTCTTACCGGATAAAGCAATTGATCTTGTTGACGAAGCG
TGCGCAACAATTCGTACAGAAATTGATTCTATGCCGACAGAATTAGATGAAGTAACGCGCCGCATTATGCAGCTAGAAAT
TGAAGAAGCGGCTCTTGGAAAAGAGAAGGACTTTGGTAGCCAAGAACGCCTCAAAACATTGCAACGTGAATTATCGGATT
TAAAAGAAGTGGCAAGTAGCATGAGAGCGAAATGGGAGAAAGAAAAAGAAGATATTCACAAAGTTCGTGACTTACGTGAA
CATTTAGAGCGTCTGCGCCGTGAATTAGAAGAAGCAGAAGGTAATTACGATTTAAATAGAGCAGCGGAACTTCGCCACGG
AAAAATTCCTGCAATTGAAAAAGAGTTAAAAGAAGCAGAAGAAATGGGCGCAAATAATAAACAAGAAAATCGTTTATTAC
GTGAGGAAGTAAGTGAAGAAGAGATCGCTGAGATTGTTTCACGCTGGACTGGTATTCCTGTCGCAAAACTCGTTGAAGGT
GAACGTGAGAAATTATTACGCTTAGAGCAAATTTTATCAGAACGTGTTATCGGACAAGAGGAAGCGGTAAGCCTAGTATC
AGATGCAGTTCTTCGCGCGCGCGCTGGTATTAAAGATCCGAACCGTCCAATTGGTTCCTTCATCTTCTTAGGACCGACGG
GGGTTGGTAAAACAGAGCTTGCCAAAACGTTAGCGCAGTCTTTATTTGATAGTGAAGAGCAAATGATTCGTATCGATATG
TCTGAGTATATGGAGAAACACGCTGTCTCACGCTTAATTGGTGCGCCTCCTGGATATGTTGGATATGAAGAGGGCGGTCA
ATTAACAGAAGCGGTAAGACGTAAACCGTATTCCGTTATTTTGTTAGACGAAATCGAAAAAGCACATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGACGGTCGCATTACAGATTCGCAAGGACGTACAGTAGACTTTAAAAACACGGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTATTAGATGGATTAGAAGAAGATGGCTCCATTAAAGAGGAATCAAGAGA
GCTTGTTATGGGGCAATTAAGAGGACATTTCCGACCAGAGTTTTTAAACCGTGTCGACGAAATTATTTTATTCAAACCTC
TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGTCGCTTAGCTGACCGTCATATTACG
GTACAATTAACAGAAGCAGCGAAAGAATTTGTTGTAGAAGCCGGATTTGATCCGATGTATGGAGCTCGTCCATTAAAACG
ATACGTACAGCGTCAAGTTGAGACGAAATTAGCGAGAGAATTAATTGCAGGTACGATTACTGACAATAGTCATGTAGTGG
TTGATGTAGAAAATAACGAATTAGTCGTTCATGTGAATTAA

Upstream 100 bases:

>100_bases
GTTTGAAAATACATAAGCAAAAATTATTGTATAAAAAAGTCAGTTGGCGTATAATCAAATCAAAGGTCAAAGAAAGTCAA
ACATTTGGAGGACTGTAAAG

Downstream 100 bases:

>100_bases
AATAAAAAAGAGTTCGGATAAAATCCGGACTCTTTTTTTAGTGCTGTTCTACTGGCTCGTTTGGAATTGCAGCTGAAATC
GCTAGTACTAATACTGCAAG

Product: ATP-dependent Clp protease, ATP-binding subunit ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 866; Mature: 866

Protein sequence:

>866_residues
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGVENLIKKKPSVTGSGAE
AGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTEEKGDISQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVKAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGANNKQENRLLREEVSEEEIAEIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEEDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VQLTEAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVN

Sequences:

>Translated_866_residues
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGVENLIKKKPSVTGSGAE
AGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTEEKGDISQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVKAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGANNKQENRLLREEVSEEEIAEIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEEDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VQLTEAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVN
>Mature_866_residues
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGVENLIKKKPSVTGSGAE
AGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTEEKGDISQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVKAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGANNKQENRLLREEVSEEEIAEIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEEDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VQLTEAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVN

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=311, Percent_Identity=39.5498392282958, Blast_Score=213, Evalue=8e-55,
Organism=Escherichia coli, GI1788943, Length=862, Percent_Identity=54.0603248259861, Blast_Score=929, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=330, Percent_Identity=43.030303030303, Blast_Score=280, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6320464, Length=715, Percent_Identity=51.6083916083916, Blast_Score=742, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=866, Percent_Identity=42.0323325635104, Blast_Score=677, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 97546; Mature: 97546

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCHHHH
KQGVENLIKKKPSVTGSGAEAGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTE
HHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
EKGDISQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEATYEALEKYGRDLVAEVKAGKI
CCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHCCCC
DPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
CCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGN
EEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCHH
MLKPMLARGELHCIGATTLDEYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERF
HHHHHHHCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEACATIRTEIDSMPTELDEVTR
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGANNKQENRLLREEVSEE
HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHH
EIAEIVSRWTGIPVAKLVEGEREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDP
HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
NRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDMSEYMEKHAVSRLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCHHHHHHHHHHHCCCCEECCCCCEEEECCEEE
IMTSNIGSAHLLDGLEEDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIK
EEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCHHHHH
GIVDKIVKELQGRLADRHITVQLTEAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARE
HHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LIAGTITDNSHVVVDVENNELVVHVN
HHHHEECCCCEEEEEECCCEEEEEEC
>Mature Secondary Structure
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCHHHH
KQGVENLIKKKPSVTGSGAEAGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTE
HHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
EKGDISQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEATYEALEKYGRDLVAEVKAGKI
CCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHCCCC
DPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
CCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGN
EEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCHH
MLKPMLARGELHCIGATTLDEYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERF
HHHHHHHCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEACATIRTEIDSMPTELDEVTR
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGANNKQENRLLREEVSEE
HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHH
EIAEIVSRWTGIPVAKLVEGEREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDP
HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
NRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDMSEYMEKHAVSRLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCHHHHHHHHHHHCCCCEECCCCCEEEECCEEE
IMTSNIGSAHLLDGLEEDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIK
EEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCHHHHH
GIVDKIVKELQGRLADRHITVQLTEAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARE
HHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LIAGTITDNSHVVVDVENNELVVHVN
HHHHEECCCCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]