Click here to switch to the map view.

The map label for this gene is mecA

Identifier: 52144141

GI number: 52144141

Start: 1196501

End: 1197184

Strand: Direct

Name: mecA

Synonym: BCZK1087

Alternate gene names: 52144141

Gene position: 1196501-1197184 (Clockwise)

Preceding gene: 52144143

Following gene: 52144139

Centisome position: 22.57

GC content: 34.94

Gene sequence:

>684_bases
TTGGATATTGAAAGAATTAATGATCATACGATGAAATTTTTTATTACGTACATTGATATAGAGGACAGAGGCTTTAATCG
TGAGGAAATTTGGTATGACCGCGAAAGAAGCGAAGAGCTCTTTTGGGAAATGATGGACGAAGCTCGTGATCATGACGATT
TCTTTATTGATGGGCCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAAAGCAGAACTT
TCAAAGGATGGACAAAAGCTAGAACTACCAATAGGTGTAGATAAAATTATAGACATTCCTCTAGATGAAGGTATTGAATC
ATTATTCCAGCAAGAATTAGTGGAAGAGGTAGAAGAACAAGCAGGAACAAACTTTAACGAAGATGGTACATTTGGCTTTT
TAATTAAGTTTAATGATTTTGAAGATGTCATTTCATTAAGTCACCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGGACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAGGAAGAAATTGATCGCATTTTAAG
TATTGTTTTAGAATACGGAGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGGAAACAAATTGTGAAAGAGC
ATGCGCTTGAAACAATTCGCAATAATTTTCCTGCTAAAACGTAG

Upstream 100 bases:

>100_bases
AGAATCTTATCATAAAATGAGAGTACAAGAATCTATTGATTTGTCATATGAGTGGGGAATCCCTTCATAACAATTCTAAG
CAGGAAGGGAGAGTTGTATT

Downstream 100 bases:

>100_bases
GCCGATTTCTGTAGTATGAAATCGGCTTTTTATATGAAGAATAGGAAAGCTTTCTTAGTAAGGAGGTAAGAGATGAAAAA
TACGTTAAAGTTGATTTTCT

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Sequences:

>Translated_227_residues
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT
>Mature_227_residues
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MECA1_BACAN (Q81TR3)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_843678.2
- RefSeq:   YP_017815.1
- RefSeq:   YP_027383.1
- EnsemblBacteria:   EBBACT00000011119
- EnsemblBacteria:   EBBACT00000015190
- EnsemblBacteria:   EBBACT00000023423
- GeneID:   1089261
- GeneID:   2819275
- GeneID:   2849130
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_1203
- KEGG:   bar:GBAA_1203
- KEGG:   bat:BAS1111
- TIGR:   BA_1203
- TIGR:   GBAA_1203
- GeneTree:   EBGT00050000001420
- HOGENOM:   HBG491202
- OMA:   VFVTKSD
- ProtClustDB:   PRK02315
- BioCyc:   BANT260799:BAS1111-MONOMER
- BioCyc:   BANT261594:GBAA1203-MONOMER
- HAMAP:   MF_01124
- InterPro:   IPR008681
- PIRSF:   PIRSF029008

Pfam domain/function: PF05389 MecA

EC number: NA

Molecular weight: Translated: 26966; Mature: 26966

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPL
CCCCCCCCCEEEEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCE
WIQVQAVDKGIEVLVTKAELSKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQ
EEEEEEECCCEEEEEEHHHHCCCCCEEEECCCHHHHEECCHHHHHHHHHHHHHHHHHHHH
AGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELYSFEDRYYVYVEFDEVLHDEE
HCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCHH
EIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPL
CCCCCCCCCEEEEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCE
WIQVQAVDKGIEVLVTKAELSKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQ
EEEEEEECCCEEEEEEHHHHCCCCCEEEECCCHHHHEECCHHHHHHHHHHHHHHHHHHHH
AGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELYSFEDRYYVYVEFDEVLHDEE
HCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCHH
EIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629