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The map label for this gene is rfbC [H]

Identifier: 52144117

GI number: 52144117

Start: 1219072

End: 1219617

Strand: Direct

Name: rfbC [H]

Synonym: BCZK1110

Alternate gene names: 52144117

Gene position: 1219072-1219617 (Clockwise)

Preceding gene: 52144120

Following gene: 52144116

Centisome position: 23.0

GC content: 37.0

Gene sequence:

>546_bases
ATGAAAGTTATAGAAACAAACTTTACCGACGCAAAATTGTTGGAACCGAGGTTATTTGGAGATGATCGTGGCTTTTTTAC
TGAAAGTTATAATAAGAAGGTGCTAGAAACATTAGGGGTTACGCATTCATTTGTACAGGATAATGTTTCGTATTCAGCGG
AAGCGGGAACGATTCGCGGATTACACTTTCAAAAAAATCCGAAAGCACAAACGAAACTTATTCAAGTTATGCAAGGGGCA
ATCTATGACGTTATCGTAGATTTGCGAAAAGATTCACCAACGTTTAAACAGTGGAGAGGATATATTTTAAGCGCAGATAA
TCATCGGCAATTATTAGTACCAAAAGGATTTGCGCACGGTTTTTGTACACTTGTCCCGCATACGATTGTTATGTATAAAG
TAGATGAGTATTATAGTGCCGATCATGACTCAGGAGTAATTTGGGACGATAAAGAATTAGCAATTCCATGGCCGGTAACA
AGTCCTATTTTGTCTGATAAAGATCGAATATTACCATTACTTCAGGAATGTAAAGATAGCTTTTGA

Upstream 100 bases:

>100_bases
GGTGGACTGATGCGGGAACTCATATTTCTCTTCAAAGAGCGAATGCGTTAGCACGGGATATAAACTTTGGTAAACAGTTT
AACGGAGAATAGGTGAAAAT

Downstream 100 bases:

>100_bases
GTAGGAGAGTTGTTTATGAATATATTAGTAACGGGTGGGGCCGGATTTATTGGAAGTAATTTTGTACATTATATGTTACA
AAGCTATGAAACATATAAAA

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MKVIETNFTDAKLLEPRLFGDDRGFFTESYNKKVLETLGVTHSFVQDNVSYSAEAGTIRGLHFQKNPKAQTKLIQVMQGA
IYDVIVDLRKDSPTFKQWRGYILSADNHRQLLVPKGFAHGFCTLVPHTIVMYKVDEYYSADHDSGVIWDDKELAIPWPVT
SPILSDKDRILPLLQECKDSF

Sequences:

>Translated_181_residues
MKVIETNFTDAKLLEPRLFGDDRGFFTESYNKKVLETLGVTHSFVQDNVSYSAEAGTIRGLHFQKNPKAQTKLIQVMQGA
IYDVIVDLRKDSPTFKQWRGYILSADNHRQLLVPKGFAHGFCTLVPHTIVMYKVDEYYSADHDSGVIWDDKELAIPWPVT
SPILSDKDRILPLLQECKDSF
>Mature_181_residues
MKVIETNFTDAKLLEPRLFGDDRGFFTESYNKKVLETLGVTHSFVQDNVSYSAEAGTIRGLHFQKNPKAQTKLIQVMQGA
IYDVIVDLRKDSPTFKQWRGYILSADNHRQLLVPKGFAHGFCTLVPHTIVMYKVDEYYSADHDSGVIWDDKELAIPWPVT
SPILSDKDRILPLLQECKDSF

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=178, Percent_Identity=50.561797752809, Blast_Score=171, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17550412, Length=172, Percent_Identity=40.1162790697674, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20682; Mature: 20682

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIETNFTDAKLLEPRLFGDDRGFFTESYNKKVLETLGVTHSFVQDNVSYSAEAGTIRG
CCEEECCCCCHHHCCCEECCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEC
LHFQKNPKAQTKLIQVMQGAIYDVIVDLRKDSPTFKQWRGYILSADNHRQLLVPKGFAHG
EEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCEEEEECCCCCH
FCTLVPHTIVMYKVDEYYSADHDSGVIWDDKELAIPWPVTSPILSDKDRILPLLQECKDS
HHHHCCCEEEEEEEHHHHCCCCCCCEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHCC
F
C
>Mature Secondary Structure
MKVIETNFTDAKLLEPRLFGDDRGFFTESYNKKVLETLGVTHSFVQDNVSYSAEAGTIRG
CCEEECCCCCHHHCCCEECCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEC
LHFQKNPKAQTKLIQVMQGAIYDVIVDLRKDSPTFKQWRGYILSADNHRQLLVPKGFAHG
EEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCEEEEECCCCCH
FCTLVPHTIVMYKVDEYYSADHDSGVIWDDKELAIPWPVTSPILSDKDRILPLLQECKDS
HHHHCCCEEEEEEEHHHHCCCCCCCEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8170390; 8157605; 12384590; 12704152 [H]