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The map label for this gene is ygbD [C]

Identifier: 52144086

GI number: 52144086

Start: 1246300

End: 1247634

Strand: Direct

Name: ygbD [C]

Synonym: BCZK1144

Alternate gene names: 52144086

Gene position: 1246300-1247634 (Clockwise)

Preceding gene: 52144087

Following gene: 52144083

Centisome position: 23.51

GC content: 39.18

Gene sequence:

>1335_bases
GTGAACTATGTCATTATTGGTGGGGATGCAGCTGGTATGAGTGCAGCTATGCAAATTGTTAGAAACGATGAAAATGCAAA
TGTTGTGACGTTAGAAAAAGGTGAAATTTATTCGTACGCGCAGTGTGGGTTACCGTATGTCATTAGTGGTGCTATCGCTT
CAACGGAAAAGTTAATCGCGCGTAATGTAAAGACGTTTCGTGATAAATACGGAATTGATGCGAAAGTACGACATGAAGTA
ACGAAAGTAGATACGGAAAAGAAAATAGTATACGCAGAGCATACGAAGACGAAAGATGTCTTTGAATTTCAGTACGATCG
ATTATTAATTGCGACCGGAGTACGTCCTGTTATGCCAGAATGGGAAGGCAGAGATTTACAAGGCGTTCATCTTTTAAAAA
CAATCCCGGATGCTGAGCGCATATTAAAAACGCTAGAAACGAATAAAGTTGAAGATGTAACCATTATTGGCGGCGGTGCA
ATTGGGCTGGAAATGGCAGAAACATTCGTCGAACTTGGTAAGAAAGTAAGAATGATTGAGAGAAATGATCATATCGGTAC
AATTTACGATGCAGACATGGCGGAATATATACATAAAGAAGCAGATAAACATAATATTGAAATTTTAACGAATGAAAATG
TAAAAGCGTTTAAAGGGAATGAACGAGTAGAAGCAGTTGAAACGGATAAAGATACGTATAAAGCAGATCTTGTTTTAGTA
TCTGTCGGAGTAAAGCCAAATACTGATTTTCTTGAAGGAACGAATATACGTACAAATCATAAAGGGGCAATCGAGGTAAA
TGCATATATGCAGACGAATGTGCAAGACGTATATGCAGCTGGTGATTGCGCGACACATTATCACGTTATAAAGGAAATTC
ATGATCATATCCCGCTCGGAACGACAGCCAATAAACAAGGGCGACTTGCTGGACTGAACATGCTGGATAAACGAAGAGCC
TTTAAAGGTACGTTAGGTACAGGCATTATTAAATTTATGGATTTGACACTTGCAAGAACAGGCTTAAATGAAAAAGAAGC
AAAAGGACTACATATCCCGTATAAAACAGTCAAAGTAGATTCCACAAATATGGCGGGCTATTATCCAAATGCGAAACCAC
TTTACTTGAAATTACTATACCGTTCTGACACGAAACAATTATTAGGCGGACAAGTAATTGGAGAAGAAGGCGTAGATAAA
CGGATTGATGTGATCGCAATGGCACTCTTCAATAAAATGAGCATTCACGATTTAGAAGATGTGGACTTAAGTTACGCACC
ACCATATAACAGCGTTTGGGACCCAATTCAGCAAGCGGCAAGACGAGCGGAATAG

Upstream 100 bases:

>100_bases
AATTTGAAGATGAAATCCTCTTTCTTTACAATAGAAGTAGGTGTTATTTCGATAAAATATGGAAAACGTAAAGAGTATGT
AAAAAAGAAGGAGTGGTAAA

Downstream 100 bases:

>100_bases
CACTTTTTAAGTGCTATTTTTTTCGTTAAAGGGTAATCATCATTTTTGTCGAATGAAGACGATTGGGAATAGTTACATAT
ATGGAAGGGGATCATTAAAA

Product: pyridine nucleotide-disulfide oxidoreductase; NADH dehydrogenase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKTFRDKYGIDAKVRHEV
TKVDTEKKIVYAEHTKTKDVFEFQYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGA
IGLEMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHNIEILTNENVKAFKGNERVEAVETDKDTYKADLVLV
SVGVKPNTDFLEGTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMLDKRRA
FKGTLGTGIIKFMDLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDK
RIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE

Sequences:

>Translated_444_residues
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKTFRDKYGIDAKVRHEV
TKVDTEKKIVYAEHTKTKDVFEFQYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGA
IGLEMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHNIEILTNENVKAFKGNERVEAVETDKDTYKADLVLV
SVGVKPNTDFLEGTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMLDKRRA
FKGTLGTGIIKFMDLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDK
RIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE
>Mature_444_residues
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKTFRDKYGIDAKVRHEV
TKVDTEKKIVYAEHTKTKDVFEFQYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGA
IGLEMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHNIEILTNENVKAFKGNERVEAVETDKDTYKADLVLV
SVGVKPNTDFLEGTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMLDKRRA
FKGTLGTGIIKFMDLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDK
RIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=325, Percent_Identity=28, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI226437568, Length=325, Percent_Identity=28, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI65787454, Length=325, Percent_Identity=28, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1789065, Length=285, Percent_Identity=23.859649122807, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786307, Length=310, Percent_Identity=24.5161290322581, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789765, Length=340, Percent_Identity=23.5294117647059, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082354, Length=301, Percent_Identity=25.5813953488372, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789915, Length=316, Percent_Identity=24.6835443037975, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559934, Length=248, Percent_Identity=26.2096774193548, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI32565766, Length=139, Percent_Identity=30.2158273381295, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585130, Length=322, Percent_Identity=26.3975155279503, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24639257, Length=323, Percent_Identity=25.077399380805, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281359715, Length=323, Percent_Identity=25.077399380805, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281359713, Length=323, Percent_Identity=25.077399380805, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24639250, Length=323, Percent_Identity=25.077399380805, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI18543267, Length=323, Percent_Identity=25.077399380805, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24639252, Length=323, Percent_Identity=25.077399380805, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24581020, Length=361, Percent_Identity=24.6537396121884, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573993, Length=361, Percent_Identity=24.6537396121884, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358499, Length=215, Percent_Identity=31.1627906976744, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 49548; Mature: 49548

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIA
CCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEHHHCCCCEEEECHHHHHHHHHH
RNVKTFRDKYGIDAKVRHEVTKVDTEKKIVYAEHTKTKDVFEFQYDRLLIATGVRPVMPE
HHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHCEEEEECCCCCCCCC
WEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMIE
CCCCCCCCEEHHHHCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHEEEEE
RNDHIGTIYDADMAEYIHKEADKHNIEILTNENVKAFKGNERVEAVETDKDTYKADLVLV
CCCCEEEEECCHHHHHHHHHCCCCCEEEEECCCEEEECCCCCEEEEECCCCCEEEEEEEE
SVGVKPNTDFLEGTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPLG
EECCCCCCCCCCCCCEEECCCCEEEEEEEEECCCHHHEECCCHHHHHHHHHHHHHCCCCC
TTANKQGRLAGLNMLDKRRAFKGTLGTGIIKFMDLTLARTGLNEKEAKGLHIPYKTVKVD
CCCCCCCCEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEEC
STNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDKRIDVIAMALFNKMSIHDLED
CCCCCCCCCCCCCEEEEEEECCCHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
VDLSYAPPYNSVWDPIQQAARRAE
CCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIA
CCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEHHHCCCCEEEECHHHHHHHHHH
RNVKTFRDKYGIDAKVRHEVTKVDTEKKIVYAEHTKTKDVFEFQYDRLLIATGVRPVMPE
HHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHCEEEEECCCCCCCCC
WEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMIE
CCCCCCCCEEHHHHCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHEEEEE
RNDHIGTIYDADMAEYIHKEADKHNIEILTNENVKAFKGNERVEAVETDKDTYKADLVLV
CCCCEEEEECCHHHHHHHHHCCCCCEEEEECCCEEEECCCCCEEEEECCCCCEEEEEEEE
SVGVKPNTDFLEGTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPLG
EECCCCCCCCCCCCCEEECCCCEEEEEEEEECCCHHHEECCCHHHHHHHHHHHHHCCCCC
TTANKQGRLAGLNMLDKRRAFKGTLGTGIIKFMDLTLARTGLNEKEAKGLHIPYKTVKVD
CCCCCCCCEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEEC
STNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDKRIDVIAMALFNKMSIHDLED
CCCCCCCCCCCCCEEEEEEECCCHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
VDLSYAPPYNSVWDPIQQAARRAE
CCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA