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The map label for this gene is phnW [H]

Identifier: 52144011

GI number: 52144011

Start: 1318982

End: 1320079

Strand: Direct

Name: phnW [H]

Synonym: BCZK1218

Alternate gene names: 52144011

Gene position: 1318982-1320079 (Clockwise)

Preceding gene: 52144012

Following gene: 52144010

Centisome position: 24.88

GC content: 34.97

Gene sequence:

>1098_bases
ATGACTGAAAATCATTACTTATTATTAACGCCAGGACCATTAACGACAACAAAGACGGTAAAAGAAGTTATGTTATACGA
TTGGTGTACGTGGGATGTTGAATATAACACGATGGTACAAAAAGTAAGAGCTAAGCTTGTATCGTTAGCAACGAAGGAAG
AAGAGAAATATACAACAGTATTAATGCAAGGAAGCGGTACGTTTTCAGTGGAAGCAGTAATTGGTTCTGTCATTCCAAAA
AACGGAAAGCTTCTTGTTTGTACAAATGGTGCATACGGTAAACGAATTGTACAAATGGCAGAGATGTTACATATAGATGT
GGTGGTCAGTCAAACAGAAGAGTGGGAGCCTACTAATATTGTAGAAGTAGAAAAGATATTACAACAAGATAAAGAGATTA
CACATATTGCAGTTGTTCATTGTGAAACAACAACAGGTATTATTAATCCAATTGTAGACGTATGTAAATTAGGGAAGCAA
TACGGAAAAGTAACACTAGTTGATGCAATGAGTAGTTTTGGTGGTATTGAAATAGATATTGCTGAGTTGCAAATTGACTT
TCTAATTAGTAGTGCGAATAAATGTATTCAAGGAGTTCCAGGGTTCGGATTTGTTATTGCAAAACGCGATGAATTGTTGA
AATGTAAAGGACAGGCACGTTCATTATCTTTAGATTTGTACGATCAGTGGGAAACGATGGAAAATCAAAATGGGAAATGG
CGTTTTACGTCACCTACACATGTTGTACATGCTTTTTATCAAGCGTTACTTGAATTAGAAAAAGAAGGCGGAGTAAGAGC
ACGTTACAATCGATATTACAACAATCAAAAACTATTAGTGAATAGAATGGGGGAAATTGGTTTTAAGCCAATCGTAAATG
AAAAATATCAATCTCCTATTATTACATCTTTCATTTATCCGGAAGGGAACTTCGAGTTTCAACAGTTATATAATGAGTTA
AAACGCTACGGATTTGTTATTTATCCTGGGAAAATTTCGAAAGTAGATACGTTCCGCATTGGAAATATTGGTGATGTACA
TGAGGAAGACATAAATCGTTTAGTAGATAGTATTGCTAAAGGGGTTGTTATAGGTTGA

Upstream 100 bases:

>100_bases
TGGAGCGCACTTTACGATTGAAACGATGCAGGAACTTGAAAGTGTAATGGAACGTATCGAGAAACAAGAACTTATTATTT
CATAAAAGGGGCATGGGATG

Downstream 100 bases:

>100_bases
AAGTATTTTGCTTAGGTGGAGCAGGTAAAATTTGTCGTGAAGCAATTTTAGATTTAGTGCAATTTTCATCTTTTGAAACG
ATTACGGTAGCTGATTTTAA

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQKVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPK
NGKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQ
YGKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQARSLSLDLYDQWETMENQNGKW
RFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPIVNEKYQSPIITSFIYPEGNFEFQQLYNEL
KRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAKGVVIG

Sequences:

>Translated_365_residues
MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQKVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPK
NGKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQ
YGKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQARSLSLDLYDQWETMENQNGKW
RFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPIVNEKYQSPIITSFIYPEGNFEFQQLYNEL
KRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAKGVVIG
>Mature_364_residues
TENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQKVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPKN
GKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQY
GKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQARSLSLDLYDQWETMENQNGKWR
FTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPIVNEKYQSPIITSFIYPEGNFEFQQLYNELK
RYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAKGVVIG

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=310, Percent_Identity=23.2258064516129, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17536281, Length=364, Percent_Identity=21.978021978022, Blast_Score=91, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 41298; Mature: 41167

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQKVRAKLVSLATKEEEKYTTV
CCCCCEEEEECCCCCHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEE
LMQGSGTFSVEAVIGSVIPKNGKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNI
EEECCCCEEHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCCCH
VEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQYGKVTLVDAMSSFGGIEIDI
HHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEEE
AELQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQARSLSLDLYDQWETMENQNGKW
EHEEEEHHHHHHHHHHCCCCCCEEEEECCCHHHHCCCCCCEEEEEHHHHHHHHCCCCCCE
RFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPIVNEKYQSPI
EECCHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCHHEEEHHHCCCCCCCCCCCCCCCE
ITSFIYPEGNFEFQQLYNELKRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAK
EEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHC
GVVIG
CCCCC
>Mature Secondary Structure 
TENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQKVRAKLVSLATKEEEKYTTV
CCCCEEEEECCCCCHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEE
LMQGSGTFSVEAVIGSVIPKNGKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNI
EEECCCCEEHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCCCH
VEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQYGKVTLVDAMSSFGGIEIDI
HHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEEE
AELQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQARSLSLDLYDQWETMENQNGKW
EHEEEEHHHHHHHHHHCCCCCCEEEEECCCHHHHCCCCCCEEEEEHHHHHHHHCCCCCCE
RFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPIVNEKYQSPI
EECCHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCHHEEEHHHCCCCCCCCCCCCCCCE
ITSFIYPEGNFEFQQLYNELKRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAK
EEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHC
GVVIG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA