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The map label for this gene is lys1

Identifier: 52144010

GI number: 52144010

Start: 1320076

End: 1321260

Strand: Direct

Name: lys1

Synonym: BCZK1219

Alternate gene names: NA

Gene position: 1320076-1321260 (Clockwise)

Preceding gene: 52144011

Following gene: 52144009

Centisome position: 24.9

GC content: 37.38

Gene sequence:

>1185_bases
TTGAAAGTATTTTGCTTAGGTGGAGCAGGTAAAATTTGTCGTGAAGCAATTTTAGATTTAGTGCAATTTTCATCTTTTGA
AACGATTACGGTAGCTGATTTTAATGAAGAAGAGGGCCTGAAAGTAGTAGAATGGCTTAACGATCCTCGCGTTGATTTTG
TGAAAGTAGATGTAACGAAGCGTGAGGATACGGTTGCAAAAATGAAGGGCTATGACATTGTAATGGATGGTACGACAATT
AAGTTAAATGGATTGTCTACTCGATGTATTGCAGAAGCAGGTTGTCACGGTGTGAACTTGAATGGATTTGGTGAAGAAAA
TGATTCGCATTCTATATTTGTTCAAAACGGAAAAACATGTTTACCTGGATTTGGAATGACGCCAGGTGTAACGCAAATGA
TGGCGATGCATGCAGCAAATCAGTTACATACGGTAGAGTCAGTTCGTGTCAGTCATGGTTCATATCGTCCAATTGCTTTT
TCTGCATCCATTGCAGAAACAACGACATATGAATATGATCCACATTTGCCATCGCGTACAGTGTATGAAGAGGGTGAGTT
TAAGCAAGTACCTCCGTTTGCACGTCCAAGAGAAATTGAATTACCGGCGCCTTATGGTAAAGCAACGCAGTATATCATAC
CGCATTCTGAAACAATTACGTTAGCAAAAGCATTAGAAAATAAAGGCGTCAAACTAATAGAGACGAGAGGAACTTGGCCA
AAAGAAAATATGCAGCTCATACGTGCTTTATATGATTATGGTATATTGCGTAATGATCAAGTTGAAATAAATGGGGAAGC
AATCGGCATAATGGATTGTATTTCGAAGTATTTATTGCAATCGAAAGAAGGACAAGAAACAGAGGTTTACGGTTATGCAC
TTCATGTAGAAGTAATAGGTATGAAAGATAATGAGAAACAAAGGCACGTATTGTATCATACACACCCGTTATCTGATGGT
TCTGTTGAAGGATGGGAAAAATTAAGAGCATATACGAGAAACGTCGGTATACCATTTGGGATTGCTACAGAGTTAATCGC
AAAAGGGGATGTAAATAAAGTTGGTGTTGTGACACCTGAGGAAGCTTTTGTAAATCCACAAGTTATTTTTGATGAATTAA
AAAAGCGTGGTATTCATATTCATGAAGAAATTTCTACTTACAAAGAAAGTTATAACTTTGTATAA

Upstream 100 bases:

>100_bases
TTTCGAAAGTAGATACGTTCCGCATTGGAAATATTGGTGATGTACATGAGGAAGACATAAATCGTTTAGTAGATAGTATT
GCTAAAGGGGTTGTTATAGG

Downstream 100 bases:

>100_bases
GTAAGGTAATGTATGAGGTAGAAATCAATGGGGTGAGGTTATGTCTGTAGTAGGTGAAGAAAGAAAGCGAACCATTCTTG
AGAAGGTAGAGTTTAAAGGG

Product: saccharopine dehydrogenase, NADP+, L-lysine forming; L-lysine dehydrogenase

Products: L-lysine; 2-oxoglutarate; NADPH; H+

Alternate protein names: L-Lysine Dehydrogenase

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKVFCLGGAGKICREAILDLVQFSSFETITVADFNEEEGLKVVEWLNDPRVDFVKVDVTKREDTVAKMKGYDIVMDGTTI
KLNGLSTRCIAEAGCHGVNLNGFGEENDSHSIFVQNGKTCLPGFGMTPGVTQMMAMHAANQLHTVESVRVSHGSYRPIAF
SASIAETTTYEYDPHLPSRTVYEEGEFKQVPPFARPREIELPAPYGKATQYIIPHSETITLAKALENKGVKLIETRGTWP
KENMQLIRALYDYGILRNDQVEINGEAIGIMDCISKYLLQSKEGQETEVYGYALHVEVIGMKDNEKQRHVLYHTHPLSDG
SVEGWEKLRAYTRNVGIPFGIATELIAKGDVNKVGVVTPEEAFVNPQVIFDELKKRGIHIHEEISTYKESYNFV

Sequences:

>Translated_394_residues
MKVFCLGGAGKICREAILDLVQFSSFETITVADFNEEEGLKVVEWLNDPRVDFVKVDVTKREDTVAKMKGYDIVMDGTTI
KLNGLSTRCIAEAGCHGVNLNGFGEENDSHSIFVQNGKTCLPGFGMTPGVTQMMAMHAANQLHTVESVRVSHGSYRPIAF
SASIAETTTYEYDPHLPSRTVYEEGEFKQVPPFARPREIELPAPYGKATQYIIPHSETITLAKALENKGVKLIETRGTWP
KENMQLIRALYDYGILRNDQVEINGEAIGIMDCISKYLLQSKEGQETEVYGYALHVEVIGMKDNEKQRHVLYHTHPLSDG
SVEGWEKLRAYTRNVGIPFGIATELIAKGDVNKVGVVTPEEAFVNPQVIFDELKKRGIHIHEEISTYKESYNFV
>Mature_394_residues
MKVFCLGGAGKICREAILDLVQFSSFETITVADFNEEEGLKVVEWLNDPRVDFVKVDVTKREDTVAKMKGYDIVMDGTTI
KLNGLSTRCIAEAGCHGVNLNGFGEENDSHSIFVQNGKTCLPGFGMTPGVTQMMAMHAANQLHTVESVRVSHGSYRPIAF
SASIAETTTYEYDPHLPSRTVYEEGEFKQVPPFARPREIELPAPYGKATQYIIPHSETITLAKALENKGVKLIETRGTWP
KENMQLIRALYDYGILRNDQVEINGEAIGIMDCISKYLLQSKEGQETEVYGYALHVEVIGMKDNEKQRHVLYHTHPLSDG
SVEGWEKLRAYTRNVGIPFGIATELIAKGDVNKVGVVTPEEAFVNPQVIFDELKKRGIHIHEEISTYKESYNFV

Specific function: Unknown

COG id: COG1748

COG function: function code E; Saccharopine dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.5.1.8

Molecular weight: Translated: 44070; Mature: 44070

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVFCLGGAGKICREAILDLVQFSSFETITVADFNEEEGLKVVEWLNDPRVDFVKVDVTK
CEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEECCCCCCEEEEEEEECC
REDTVAKMKGYDIVMDGTTIKLNGLSTRCIAEAGCHGVNLNGFGEENDSHSIFVQNGKTC
CCHHHHHHCCCEEEECCCEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEE
LPGFGMTPGVTQMMAMHAANQLHTVESVRVSHGSYRPIAFSASIAETTTYEYDPHLPSRT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCCCEEEEECCCCCCCC
VYEEGEFKQVPPFARPREIELPAPYGKATQYIIPHSETITLAKALENKGVKLIETRGTWP
CCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEECCCCC
KENMQLIRALYDYGILRNDQVEINGEAIGIMDCISKYLLQSKEGQETEVYGYALHVEVIG
HHHHHHHHHHHHHCCCCCCEEEECCCEEEHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEE
MKDNEKQRHVLYHTHPLSDGSVEGWEKLRAYTRNVGIPFGIATELIAKGDVNKVGVVTPE
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCH
EAFVNPQVIFDELKKRGIHIHEEISTYKESYNFV
HHHCCHHHHHHHHHHCCCEEHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVFCLGGAGKICREAILDLVQFSSFETITVADFNEEEGLKVVEWLNDPRVDFVKVDVTK
CEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEECCCCCCEEEEEEEECC
REDTVAKMKGYDIVMDGTTIKLNGLSTRCIAEAGCHGVNLNGFGEENDSHSIFVQNGKTC
CCHHHHHHCCCEEEECCCEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEE
LPGFGMTPGVTQMMAMHAANQLHTVESVRVSHGSYRPIAFSASIAETTTYEYDPHLPSRT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCCCEEEEECCCCCCCC
VYEEGEFKQVPPFARPREIELPAPYGKATQYIIPHSETITLAKALENKGVKLIETRGTWP
CCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEECCCCC
KENMQLIRALYDYGILRNDQVEINGEAIGIMDCISKYLLQSKEGQETEVYGYALHVEVIG
HHHHHHHHHHHHHCCCCCCEEEECCCEEEHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEE
MKDNEKQRHVLYHTHPLSDGSVEGWEKLRAYTRNVGIPFGIATELIAKGDVNKVGVVTPE
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCH
EAFVNPQVIFDELKKRGIHIHEEISTYKESYNFV
HHHCCHHHHHHHHHHCCCEEHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N6-(L-1,3-dicarboxypropyl)-L-lysine; NADP+; H2O

Specific reaction: N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O = L-lysine + 2-oxoglutarate + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA