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The map label for this gene is mecA2 [H]

Identifier: 52143858

GI number: 52143858

Start: 1464629

End: 1465237

Strand: Direct

Name: mecA2 [H]

Synonym: BCZK1371

Alternate gene names: 52143858

Gene position: 1464629-1465237 (Clockwise)

Preceding gene: 52143859

Following gene: 52143857

Centisome position: 27.63

GC content: 35.8

Gene sequence:

>609_bases
ATGAGGCTGGAACGATTAAATTACAATAAGATAAAAATTTTCTTAACATTTGATGATTTATCTGAACGAGGATTAACGAA
AGAAGATTTGTGGAGAAATGCACCGAAAGTACAGCAATTATTTCGTGATATGATGCAAGAAGCAAATAAAGAATTGGGAT
TTGAAGCGGATGGCCCGATTGCAGTTGAAGTATTTTCTCTACAAGCGCAAGGAATGGTCGTAATTGTAACGAAAGAACAT
CAAGAAGCGGATACAGATGATGAGTTCCGTGACGAATTTATTGAAATGCAAGTGACTCTAGATGAAAGCGAGCATATCCT
TTATGAGTTTGCTACACTAGATGACGTAATTAACCTGTCGAATCGTTTATATAACCTTGATGTAACTGGCGGAAAATTAT
ATACGTGGGATGGGCGTTTCTATCTTTGGATGGAAGAAGAGGAGCAAATACAATTACTGAAGGCAGATTTTATAGCTATT
TTAGCGGAATATGGTAATCCGTCTACAGCAACTATTTATCGTCTAGTGGAGTATGGTAAAGAATTAATGGCTTCTCAAGC
AATTGAACAAATACACAATTACTTTGTGAAAAAACAAAACCTTAGCTAA

Upstream 100 bases:

>100_bases
ATTGGTTAAAAATGTTAGAATAGTTGTTCGAAAAGAACCATCTATTTTCTATTTCATATAATAAAAATTATATTCATTGG
TTGCGTAGGGAGGGTATGAG

Downstream 100 bases:

>100_bases
TATAACATAGCTAAGGTTTTGTTTTTTATTTTACTTAAATGTATCTTTTTCAAGTGCTGTATTTAAGTGAAATAAAAAAT
ATTTAAATATTTAAGTATTT

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPIAVEVFSLQAQGMVVIVTKEH
QEADTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLSNRLYNLDVTGGKLYTWDGRFYLWMEEEEQIQLLKADFIAI
LAEYGNPSTATIYRLVEYGKELMASQAIEQIHNYFVKKQNLS

Sequences:

>Translated_202_residues
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPIAVEVFSLQAQGMVVIVTKEH
QEADTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLSNRLYNLDVTGGKLYTWDGRFYLWMEEEEQIQLLKADFIAI
LAEYGNPSTATIYRLVEYGKELMASQAIEQIHNYFVKKQNLS
>Mature_202_residues
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPIAVEVFSLQAQGMVVIVTKEH
QEADTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLSNRLYNLDVTGGKLYTWDGRFYLWMEEEEQIQLLKADFIAI
LAEYGNPSTATIYRLVEYGKELMASQAIEQIHNYFVKKQNLS

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 23698; Mature: 23698

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPI
CCCCCCCCCEEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCE
AVEVFSLQAQGMVVIVTKEHQEADTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLS
EEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHEEEEEEECCCCEEEEHHHHHHHHHHHH
NRLYNLDVTGGKLYTWDGRFYLWMEEEEQIQLLKADFIAILAEYGNPSTATIYRLVEYGK
HHEEEEEECCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ELMASQAIEQIHNYFVKKQNLS
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPI
CCCCCCCCCEEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCE
AVEVFSLQAQGMVVIVTKEHQEADTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLS
EEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHEEEEEEECCCCEEEEHHHHHHHHHHHH
NRLYNLDVTGGKLYTWDGRFYLWMEEEEQIQLLKADFIAILAEYGNPSTATIYRLVEYGK
HHEEEEEECCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ELMASQAIEQIHNYFVKKQNLS
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]