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The map label for this gene is nagA [H]

Identifier: 52143594

GI number: 52143594

Start: 1728025

End: 1729188

Strand: Direct

Name: nagA [H]

Synonym: BCZK1640

Alternate gene names: 52143594

Gene position: 1728025-1729188 (Clockwise)

Preceding gene: 52143595

Following gene: 52143593

Centisome position: 32.6

GC content: 36.86

Gene sequence:

>1164_bases
ATGAACTACTATGTCAAAGCATCTATGTATCTACTAGAAGATGGTGTTCGTGAGGGTGGATATTTACATATTGTAAATGG
CTACTTTCTAAAACATGTTGAAGAAATAGTAGACGGAGCGTTAGTAATGGATTTTGAAGGAAGTATTATTTCTCCAGGAT
TTGTGGATACACATATTCACGGTGTAGCGGGACATGATGTAATGGATAGCACATATGAATCGTTAAACAATATTTCTATT
ATGTTATTGGAAAATGGTGTTACGAGTTTTTTACCTACAACGTTAACTGGTTATTCGGAAAATACAATGAAAGCTTTAAA
AAATATAGCTCATGCAAAAAAAAGAGGAGTGGAAGGGGCGAATATTATTGGAGCTTTTCTTGAGGGACCTTGTTTTACGG
AGGTCTATAAAGGTGCACAAAACTCTAAATATTTTATTGATCCAACCATTGAAATGTTAGAGGAGTGGATTGTTGCATCA
GAAGGGACAATTAAAAAAATTGCCATGGCACCAGAGAGGAAAGGTACTATTGCGTGTATACATCATGCTGTGAAAAAGAA
TATTCATGTAGCAATTGGGCATACGAATGCAAACTATGAGATATGCCAGAATGCGATTCAAGCAGGAGCGACGATTTTTG
TGCATACGTTTAATGGAATGAAAGGATTACATCACCGTGAACCTGGCGTTGTTGGAGCGGTACTCTCAACTGAGCATGTG
TATGGTGAAATCATTGTAGATGGACATCATGTACATCCAAGCGTAGTGAATATTTTATATAAATGTAAAGGATACGACAA
AACTTGTTTAGTTAGTGACTGTATGCGAGCGGGCTTATTAGGGGATGGCACATATAATTTAGGAGAATTTGTTGTCCAAG
TGCAAGACGGCATTGCCCGAACAGAGGCGGGTTCTTTAGCAGGAAGTACACTTCGATTTATTGATGGTGTGAAGAATATA
GAGAAATGGACAAATGCATCGTTATGGGAATGTGTTCATATGGGATCGTTAATTCCTGCTAAAAGTATTGGAGTTGATAA
TGAAATTGGAAGTATAGCACCAGGGAAAAGAGCTGATTTTCTTATATTAACAGAGGATTTAGATCTTATAGGAACAGTTG
TAGGGGGAGAAATGAAATATAAAAAGAATAAAGAGAGGATTTGA

Upstream 100 bases:

>100_bases
ATTAGGGATTACTCCAGATAACCCTTGTCCAAGTGGAAGTGTAAATCGTATCGTTCGAGGGGTAACAGTACATCCTTATA
AAGGAAAGGAATAGCAATTT

Downstream 100 bases:

>100_bases
GAGTATGCTTGTTTCAACTCAATTTATACTGAGAAATGCACAAGAACAGGGTTATGCGGTTCCGGCTTTTAATATTCATA
ATTTAGAAACTTTAAAAGCA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNYYVKASMYLLEDGVREGGYLHIVNGYFLKHVEEIVDGALVMDFEGSIISPGFVDTHIHGVAGHDVMDSTYESLNNISI
MLLENGVTSFLPTTLTGYSENTMKALKNIAHAKKRGVEGANIIGAFLEGPCFTEVYKGAQNSKYFIDPTIEMLEEWIVAS
EGTIKKIAMAPERKGTIACIHHAVKKNIHVAIGHTNANYEICQNAIQAGATIFVHTFNGMKGLHHREPGVVGAVLSTEHV
YGEIIVDGHHVHPSVVNILYKCKGYDKTCLVSDCMRAGLLGDGTYNLGEFVVQVQDGIARTEAGSLAGSTLRFIDGVKNI
EKWTNASLWECVHMGSLIPAKSIGVDNEIGSIAPGKRADFLILTEDLDLIGTVVGGEMKYKKNKERI

Sequences:

>Translated_387_residues
MNYYVKASMYLLEDGVREGGYLHIVNGYFLKHVEEIVDGALVMDFEGSIISPGFVDTHIHGVAGHDVMDSTYESLNNISI
MLLENGVTSFLPTTLTGYSENTMKALKNIAHAKKRGVEGANIIGAFLEGPCFTEVYKGAQNSKYFIDPTIEMLEEWIVAS
EGTIKKIAMAPERKGTIACIHHAVKKNIHVAIGHTNANYEICQNAIQAGATIFVHTFNGMKGLHHREPGVVGAVLSTEHV
YGEIIVDGHHVHPSVVNILYKCKGYDKTCLVSDCMRAGLLGDGTYNLGEFVVQVQDGIARTEAGSLAGSTLRFIDGVKNI
EKWTNASLWECVHMGSLIPAKSIGVDNEIGSIAPGKRADFLILTEDLDLIGTVVGGEMKYKKNKERI
>Mature_387_residues
MNYYVKASMYLLEDGVREGGYLHIVNGYFLKHVEEIVDGALVMDFEGSIISPGFVDTHIHGVAGHDVMDSTYESLNNISI
MLLENGVTSFLPTTLTGYSENTMKALKNIAHAKKRGVEGANIIGAFLEGPCFTEVYKGAQNSKYFIDPTIEMLEEWIVAS
EGTIKKIAMAPERKGTIACIHHAVKKNIHVAIGHTNANYEICQNAIQAGATIFVHTFNGMKGLHHREPGVVGAVLSTEHV
YGEIIVDGHHVHPSVVNILYKCKGYDKTCLVSDCMRAGLLGDGTYNLGEFVVQVQDGIARTEAGSLAGSTLRFIDGVKNI
EKWTNASLWECVHMGSLIPAKSIGVDNEIGSIAPGKRADFLILTEDLDLIGTVVGGEMKYKKNKERI

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=386, Percent_Identity=27.4611398963731, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI224922791, Length=378, Percent_Identity=27.5132275132275, Blast_Score=135, Evalue=6e-32,
Organism=Escherichia coli, GI1786892, Length=341, Percent_Identity=30.4985337243402, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17553768, Length=390, Percent_Identity=29.4871794871795, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI19920392, Length=382, Percent_Identity=31.6753926701571, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI281361140, Length=395, Percent_Identity=30.126582278481, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 42200; Mature: 42200

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYYVKASMYLLEDGVREGGYLHIVNGYFLKHVEEIVDGALVMDFEGSIISPGFVDTHIH
CCEEEEEEEHEECCCCCCCCEEEEECHHHHHHHHHHHCCEEEEEECCCEECCCCCCCEEC
GVAGHDVMDSTYESLNNISIMLLENGVTSFLPTTLTGYSENTMKALKNIAHAKKRGVEGA
CCCCCHHHHHHHHHHCCEEEEEEECCCHHHCCHHHCCCCHHHHHHHHHHHHHHHHCCCCH
NIIGAFLEGPCFTEVYKGAQNSKYFIDPTIEMLEEWIVASEGTIKKIAMAPERKGTIACI
HHHHHHHCCCHHHHHHCCCCCCCEEECHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
HHAVKKNIHVAIGHTNANYEICQNAIQAGATIFVHTFNGMKGLHHREPGVVGAVLSTEHV
HHHHHCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCE
YGEIIVDGHHVHPSVVNILYKCKGYDKTCLVSDCMRAGLLGDGTYNLGEFVVQVQDGIAR
EEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHH
TEAGSLAGSTLRFIDGVKNIEKWTNASLWECVHMGSLIPAKSIGVDNEIGSIAPGKRADF
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCE
LILTEDLDLIGTVVGGEMKYKKNKERI
EEEECCCHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure
MNYYVKASMYLLEDGVREGGYLHIVNGYFLKHVEEIVDGALVMDFEGSIISPGFVDTHIH
CCEEEEEEEHEECCCCCCCCEEEEECHHHHHHHHHHHCCEEEEEECCCEECCCCCCCEEC
GVAGHDVMDSTYESLNNISIMLLENGVTSFLPTTLTGYSENTMKALKNIAHAKKRGVEGA
CCCCCHHHHHHHHHHCCEEEEEEECCCHHHCCHHHCCCCHHHHHHHHHHHHHHHHCCCCH
NIIGAFLEGPCFTEVYKGAQNSKYFIDPTIEMLEEWIVASEGTIKKIAMAPERKGTIACI
HHHHHHHCCCHHHHHHCCCCCCCEEECHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
HHAVKKNIHVAIGHTNANYEICQNAIQAGATIFVHTFNGMKGLHHREPGVVGAVLSTEHV
HHHHHCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCE
YGEIIVDGHHVHPSVVNILYKCKGYDKTCLVSDCMRAGLLGDGTYNLGEFVVQVQDGIAR
EEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHH
TEAGSLAGSTLRFIDGVKNIEKWTNASLWECVHMGSLIPAKSIGVDNEIGSIAPGKRADF
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCE
LILTEDLDLIGTVVGGEMKYKKNKERI
EEEECCCHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969210 [H]