Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 52143586

GI number: 52143586

Start: 1737040

End: 1738023

Strand: Reverse

Name: fabH [H]

Synonym: BCZK1648

Alternate gene names: 52143586

Gene position: 1738023-1737040 (Counterclockwise)

Preceding gene: 52143584

Following gene: 52143601

Centisome position: 32.79

GC content: 36.38

Gene sequence:

>984_bases
ATGCATTCTAAATCTCGCATTACCGCAATTGGTACTTATGTTCCAAATCAAATATTATCTAATAATGATTTAGAAAAAAT
GATCGATACGAATGATGAATGGATTGTACAAAGAACAGGAATGAAGGAAAGAAGAATTGCTAGCGAAGATGAATACTCCT
CACACTTAGCCATTAAAGCCATTGAAAATTTATGTACAACATTTAAAAAGAACTTAGAAGATATCGACTGTATCATCGTC
GCTACAACGACTGCTGACTTTGTTTTTCCTAGTGTTGCGTGTCAAATACAACAACACTTCAACATACCTCATACAATGGC
ATTTGATTTAAATGCCACTTGCGCTGGTTTCACATATGGCTTGCACGTCGGTAATAGCTTGATTACTTCTGGATCACATA
AAAAAGTACTTGTCGTAGCGACAGAGACATTATCAAAAGTTACTGATTACTCCGATAGAACGACCTGCATTTTATTTGGC
GATGGTGCTGGAGCTATTTTATTAGAAAGAGATGAAAACAAACCAAGCTTTATCGCGTATCATATGGGCACAAATGGGCA
CGGCGGTATTCATCTATATAGAACAAACTTATCTACTACTATGAATGACACCCCACTGCAAACAAATGAAAAAATCGTTC
AAAATGGAAGAGAAGTATATAAATGGGCAACACGTACGGTGCCAGCAGGTATAAAAGAACTATTACATACTGCAAATATG
CAAAAAGATGATATAGACTGGCTCATTCCTCATAGCGCTAACTTACGCATGATTGAATCTATTTGTGAAAAATCTCAAAT
TCCAATACAAAAAACATTAACGAGCGTGGAATATATGGGGAATACATCTTCTGTCTCTATTCCACTCGCTCTAGATTTAG
CTAGAAAAGAAGGGAAATTAAATAACGGAGACACACTTTTACTGTACGGATTTGGTGGTGGTCTTACGCATTTAGGGCTT
ATTGTGGAATGGGATTTAAGCTAA

Upstream 100 bases:

>100_bases
AAGTTAAGCATTATCACTTCAATACAATAAAAGTCTTTATTGACATTTTTATAACCTGATATTAGTATCAGGTTATAAAA
ATAAGTTAGGAGATGTTCCC

Downstream 100 bases:

>100_bases
ACATATAAAAAAGAGGTTCTAGTTAGTAACTAGAACCTCACTTCAATTTCGTTACCCTTTTCGGGACCATATCACAACAG
GGATAAGCATGAAAGCTAAT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 2; Beta-ketoacyl-ACP synthase III 2; KAS III 2 [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MHSKSRITAIGTYVPNQILSNNDLEKMIDTNDEWIVQRTGMKERRIASEDEYSSHLAIKAIENLCTTFKKNLEDIDCIIV
ATTTADFVFPSVACQIQQHFNIPHTMAFDLNATCAGFTYGLHVGNSLITSGSHKKVLVVATETLSKVTDYSDRTTCILFG
DGAGAILLERDENKPSFIAYHMGTNGHGGIHLYRTNLSTTMNDTPLQTNEKIVQNGREVYKWATRTVPAGIKELLHTANM
QKDDIDWLIPHSANLRMIESICEKSQIPIQKTLTSVEYMGNTSSVSIPLALDLARKEGKLNNGDTLLLYGFGGGLTHLGL
IVEWDLS

Sequences:

>Translated_327_residues
MHSKSRITAIGTYVPNQILSNNDLEKMIDTNDEWIVQRTGMKERRIASEDEYSSHLAIKAIENLCTTFKKNLEDIDCIIV
ATTTADFVFPSVACQIQQHFNIPHTMAFDLNATCAGFTYGLHVGNSLITSGSHKKVLVVATETLSKVTDYSDRTTCILFG
DGAGAILLERDENKPSFIAYHMGTNGHGGIHLYRTNLSTTMNDTPLQTNEKIVQNGREVYKWATRTVPAGIKELLHTANM
QKDDIDWLIPHSANLRMIESICEKSQIPIQKTLTSVEYMGNTSSVSIPLALDLARKEGKLNNGDTLLLYGFGGGLTHLGL
IVEWDLS
>Mature_327_residues
MHSKSRITAIGTYVPNQILSNNDLEKMIDTNDEWIVQRTGMKERRIASEDEYSSHLAIKAIENLCTTFKKNLEDIDCIIV
ATTTADFVFPSVACQIQQHFNIPHTMAFDLNATCAGFTYGLHVGNSLITSGSHKKVLVVATETLSKVTDYSDRTTCILFG
DGAGAILLERDENKPSFIAYHMGTNGHGGIHLYRTNLSTTMNDTPLQTNEKIVQNGREVYKWATRTVPAGIKELLHTANM
QKDDIDWLIPHSANLRMIESICEKSQIPIQKTLTSVEYMGNTSSVSIPLALDLARKEGKLNNGDTLLLYGFGGGLTHLGL
IVEWDLS

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=312, Percent_Identity=39.1025641025641, Blast_Score=234, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36236; Mature: 36236

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSKSRITAIGTYVPNQILSNNDLEKMIDTNDEWIVQRTGMKERRIASEDEYSSHLAIKA
CCCCCEEEEEECCCCHHHHCCCCHHHHHCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHH
IENLCTTFKKNLEDIDCIIVATTTADFVFPSVACQIQQHFNIPHTMAFDLNATCAGFTYG
HHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEE
LHVGNSLITSGSHKKVLVVATETLSKVTDYSDRTTCILFGDGAGAILLERDENKPSFIAY
EECCCHHEECCCCCEEEEEEEHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCEEEE
HMGTNGHGGIHLYRTNLSTTMNDTPLQTNEKIVQNGREVYKWATRTVPAGIKELLHTANM
ECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCC
QKDDIDWLIPHSANLRMIESICEKSQIPIQKTLTSVEYMGNTSSVSIPLALDLARKEGKL
CCCCCCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEEEEHHHCCCC
NNGDTLLLYGFGGGLTHLGLIVEWDLS
CCCCEEEEEECCCCCCEEEEEEEEECC
>Mature Secondary Structure
MHSKSRITAIGTYVPNQILSNNDLEKMIDTNDEWIVQRTGMKERRIASEDEYSSHLAIKA
CCCCCEEEEEECCCCHHHHCCCCHHHHHCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHH
IENLCTTFKKNLEDIDCIIVATTTADFVFPSVACQIQQHFNIPHTMAFDLNATCAGFTYG
HHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEE
LHVGNSLITSGSHKKVLVVATETLSKVTDYSDRTTCILFGDGAGAILLERDENKPSFIAY
EECCCHHEECCCCCEEEEEEEHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCEEEE
HMGTNGHGGIHLYRTNLSTTMNDTPLQTNEKIVQNGREVYKWATRTVPAGIKELLHTANM
ECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCC
QKDDIDWLIPHSANLRMIESICEKSQIPIQKTLTSVEYMGNTSSVSIPLALDLARKEGKL
CCCCCCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEEEEHHHCCCC
NNGDTLLLYGFGGGLTHLGLIVEWDLS
CCCCEEEEEECCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]