Click here to switch to the map view.

The map label for this gene is dppE [H]

Identifier: 52143551

GI number: 52143551

Start: 1776274

End: 1777902

Strand: Direct

Name: dppE [H]

Synonym: BCZK1683

Alternate gene names: 52143551

Gene position: 1776274-1777902 (Clockwise)

Preceding gene: 161763544

Following gene: 52143549

Centisome position: 33.51

GC content: 33.58

Gene sequence:

>1629_bases
ATGAAGTGGAAAAAGAGCCATTTAATGGTAATGGCACTTGTTATATCTTTATTATTAACAGCTTGTAATAATAAGGAAAA
TAAAAGTGATGCAGAGTCAAAAAAACAAGTATTAAATGTAACAGTATCAGAAGAGATTCCTTCTCTTGATACCGCGAAAA
CGATGGATGGTACGTCAGCGCACGTTATGCAAAACATATTTGAAGGGTTGTATGTATTAGATGATCAAGATCAGCCTATT
CCAGCGGTAGCAAAATCGTTTAAAAGAAGTGAAGATGGTAAAAAATATACATTTGATTTGCGTAAAGATGCAAAATGGTC
AAATGGGGACAATGTGACAGCTCATGATTTTATGTTTGCGTGGAAACGTGCAATTACCCCTGAAACAGCGTCTCAATATG
CGTCCATGCTCTTTTATGTAAAAAATGCGAAAGAGATTAATAAGGGGACGATGCCTCTTGATGAACTTGGGGTTACGGTT
ATAAATGATTATAAGTTAGAGGTGGAACTAGAACAGCCAATTCCTTATTTTTTACAGTTGTTAGCACTACCTATATACCT
ACCACAGCATGAATCATTTTTGAAAGAACAAGGAAAGAACTATGCATTGGAACCTAGTAATCTCCTATATAACGGTCCAT
TTATATTAGAGAAATGGAAGCATGAACAAGAGTTTCAATTAAAGAAGAATGCTACCTATTGGGATCAAAAGAAAGTGAAA
TTAGATGAAATAAACTTTCAAATTGTAAAGGATACAATGACGGCTGTTAATTTATACGAAGCTGGTAATTTGGATAGGGT
ACCTATTAATTCTCAATTTGTAGACAAGTATAAAGGGAATAAGGAATTACATATGTCGAGTGATTCTGGAATTGCTATGC
TACGTTTTAATGAAAAAAATAATGCATTAGCAAATAAAAAGGTACGTCAATCTATTTCATTAGCGTTAAATAAAGAGGAC
TTCGTTGCTCACTTTATTAATAACGGAGCAAAACCTGCCAGTGGATTAGTACCAGCTGGTCATATAAATGAAGAGACTGG
TAAAGATTTTAGAAAAGAAAACGGAAATCTTTCTTCATATGATTTGCAAAATGCGAAAAAGATTTGGAAAGAAGCGAAAA
AAGAGCTTGGGGTAGAACAAGTAAACCTCGAGTTATTAACGTTTGAACAAGATAATGCAAAACGTATGGCAGAATATATA
AAAGGTGATTTAGAAAAGAATTTACAAGGACTAACGATACAAATTAAACAACAGCCATTTAAGCAAAAATTACAGTTAGA
ACAAACAGGTGATTACGATATAACTATGGCAAATTGGGGACCTGACTATAAAGACCCAATTAGTTATTTAGAATTATTTA
CGACAGGTAATCCGAATAATAAAATGAATTACTCTAATTCTCGTTATGATGAATTAATAAAGAAAGCGAAAACTGATTTT
GTACTAGAACCAGAGAAACGATGGGAAGCATTGCTAGAAGCTGAGCAGGTATTATTAGAAGATGCAGCTGTAGCGCCGCT
GTATCATATTGGTTCAGCATATGTACAAAAGGATTACGTAAAGGGAATTGAAAAGCATCAATTTGGTGGTGTTTATACTT
ATAAGAATGCTTATATCGCTAATGAATAA

Upstream 100 bases:

>100_bases
TGAACGAATAAATATTCAAAAGAATGTCGCATCTTTCTGGTAGTATTTCTGCTATAATATATAACGTTTTATAATATTAT
ATTTTTAAGGAGAACAACTT

Downstream 100 bases:

>100_bases
ATACAAAAAACCTTACTTTTTAAAAGTAAGGTTTTTTACAGAGGAGCAGGGAAATCCTTTGGTAGTGTTCCTAGCATATA
AAGAAGAGAAGTGCAAAATT

Product: oligopeptide ABC transporter, oligopeptide-binding protein, oppA-like

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MKWKKSHLMVMALVISLLLTACNNKENKSDAESKKQVLNVTVSEEIPSLDTAKTMDGTSAHVMQNIFEGLYVLDDQDQPI
PAVAKSFKRSEDGKKYTFDLRKDAKWSNGDNVTAHDFMFAWKRAITPETASQYASMLFYVKNAKEINKGTMPLDELGVTV
INDYKLEVELEQPIPYFLQLLALPIYLPQHESFLKEQGKNYALEPSNLLYNGPFILEKWKHEQEFQLKKNATYWDQKKVK
LDEINFQIVKDTMTAVNLYEAGNLDRVPINSQFVDKYKGNKELHMSSDSGIAMLRFNEKNNALANKKVRQSISLALNKED
FVAHFINNGAKPASGLVPAGHINEETGKDFRKENGNLSSYDLQNAKKIWKEAKKELGVEQVNLELLTFEQDNAKRMAEYI
KGDLEKNLQGLTIQIKQQPFKQKLQLEQTGDYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNSRYDELIKKAKTDF
VLEPEKRWEALLEAEQVLLEDAAVAPLYHIGSAYVQKDYVKGIEKHQFGGVYTYKNAYIANE

Sequences:

>Translated_542_residues
MKWKKSHLMVMALVISLLLTACNNKENKSDAESKKQVLNVTVSEEIPSLDTAKTMDGTSAHVMQNIFEGLYVLDDQDQPI
PAVAKSFKRSEDGKKYTFDLRKDAKWSNGDNVTAHDFMFAWKRAITPETASQYASMLFYVKNAKEINKGTMPLDELGVTV
INDYKLEVELEQPIPYFLQLLALPIYLPQHESFLKEQGKNYALEPSNLLYNGPFILEKWKHEQEFQLKKNATYWDQKKVK
LDEINFQIVKDTMTAVNLYEAGNLDRVPINSQFVDKYKGNKELHMSSDSGIAMLRFNEKNNALANKKVRQSISLALNKED
FVAHFINNGAKPASGLVPAGHINEETGKDFRKENGNLSSYDLQNAKKIWKEAKKELGVEQVNLELLTFEQDNAKRMAEYI
KGDLEKNLQGLTIQIKQQPFKQKLQLEQTGDYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNSRYDELIKKAKTDF
VLEPEKRWEALLEAEQVLLEDAAVAPLYHIGSAYVQKDYVKGIEKHQFGGVYTYKNAYIANE
>Mature_542_residues
MKWKKSHLMVMALVISLLLTACNNKENKSDAESKKQVLNVTVSEEIPSLDTAKTMDGTSAHVMQNIFEGLYVLDDQDQPI
PAVAKSFKRSEDGKKYTFDLRKDAKWSNGDNVTAHDFMFAWKRAITPETASQYASMLFYVKNAKEINKGTMPLDELGVTV
INDYKLEVELEQPIPYFLQLLALPIYLPQHESFLKEQGKNYALEPSNLLYNGPFILEKWKHEQEFQLKKNATYWDQKKVK
LDEINFQIVKDTMTAVNLYEAGNLDRVPINSQFVDKYKGNKELHMSSDSGIAMLRFNEKNNALANKKVRQSISLALNKED
FVAHFINNGAKPASGLVPAGHINEETGKDFRKENGNLSSYDLQNAKKIWKEAKKELGVEQVNLELLTFEQDNAKRMAEYI
KGDLEKNLQGLTIQIKQQPFKQKLQLEQTGDYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNSRYDELIKKAKTDF
VLEPEKRWEALLEAEQVLLEDAAVAPLYHIGSAYVQKDYVKGIEKHQFGGVYTYKNAYIANE

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=519, Percent_Identity=29.6724470134875, Blast_Score=226, Evalue=4e-60,
Organism=Escherichia coli, GI87081878, Length=525, Percent_Identity=27.047619047619, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1789397, Length=523, Percent_Identity=26.5774378585086, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1789966, Length=483, Percent_Identity=26.7080745341615, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787052, Length=416, Percent_Identity=24.5192307692308, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787762, Length=464, Percent_Identity=23.0603448275862, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787551, Length=572, Percent_Identity=20.6293706293706, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789887, Length=364, Percent_Identity=24.1758241758242, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 62042; Mature: 62042

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWKKSHLMVMALVISLLLTACNNKENKSDAESKKQVLNVTVSEEIPSLDTAKTMDGTSA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEEEHHCCCCCCCCCCCCCCHH
HVMQNIFEGLYVLDDQDQPIPAVAKSFKRSEDGKKYTFDLRKDAKWSNGDNVTAHDFMFA
HHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHH
WKRAITPETASQYASMLFYVKNAKEINKGTMPLDELGVTVINDYKLEVELEQPIPYFLQL
HHHHCCCHHHHHHHHHHHHHHCHHHCCCCCCCHHHCCEEEEECEEEEEEECCCCHHHHHH
LALPIYLPQHESFLKEQGKNYALEPSNLLYNGPFILEKWKHEQEFQLKKNATYWDQKKVK
HHHHHCCCCHHHHHHHCCCCCCCCCCCEEECCCCHHHHHCCCHHHHHHCCCCCCCCCCCE
LDEINFQIVKDTMTAVNLYEAGNLDRVPINSQFVDKYKGNKELHMSSDSGIAMLRFNEKN
EECCCEEEEEHHHHHHHHEECCCCCCCCCCHHHHHHHCCCCEEEECCCCCEEEEEECCCC
NALANKKVRQSISLALNKEDFVAHFINNGAKPASGLVPAGHINEETGKDFRKENGNLSSY
CCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCH
DLQNAKKIWKEAKKELGVEQVNLELLTFEQDNAKRMAEYIKGDLEKNLQGLTIQIKQQPF
HHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCH
KQKLQLEQTGDYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNSRYDELIKKAKTDF
HHHHHHHCCCCEEEEECCCCCCCCCHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHCCCC
VLEPEKRWEALLEAEQVLLEDAAVAPLYHIGSAYVQKDYVKGIEKHQFGGVYTYKNAYIA
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEC
NE
CC
>Mature Secondary Structure
MKWKKSHLMVMALVISLLLTACNNKENKSDAESKKQVLNVTVSEEIPSLDTAKTMDGTSA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEEEHHCCCCCCCCCCCCCCHH
HVMQNIFEGLYVLDDQDQPIPAVAKSFKRSEDGKKYTFDLRKDAKWSNGDNVTAHDFMFA
HHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHH
WKRAITPETASQYASMLFYVKNAKEINKGTMPLDELGVTVINDYKLEVELEQPIPYFLQL
HHHHCCCHHHHHHHHHHHHHHCHHHCCCCCCCHHHCCEEEEECEEEEEEECCCCHHHHHH
LALPIYLPQHESFLKEQGKNYALEPSNLLYNGPFILEKWKHEQEFQLKKNATYWDQKKVK
HHHHHCCCCHHHHHHHCCCCCCCCCCCEEECCCCHHHHHCCCHHHHHHCCCCCCCCCCCE
LDEINFQIVKDTMTAVNLYEAGNLDRVPINSQFVDKYKGNKELHMSSDSGIAMLRFNEKN
EECCCEEEEEHHHHHHHHEECCCCCCCCCCHHHHHHHCCCCEEEECCCCCEEEEEECCCC
NALANKKVRQSISLALNKEDFVAHFINNGAKPASGLVPAGHINEETGKDFRKENGNLSSY
CCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCH
DLQNAKKIWKEAKKELGVEQVNLELLTFEQDNAKRMAEYIKGDLEKNLQGLTIQIKQQPF
HHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCH
KQKLQLEQTGDYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNSRYDELIKKAKTDF
HHHHHHHCCCCEEEEECCCCCCCCCHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHCCCC
VLEPEKRWEALLEAEQVLLEDAAVAPLYHIGSAYVQKDYVKGIEKHQFGGVYTYKNAYIA
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEC
NE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]