Click here to switch to the map view.

The map label for this gene is cobW [H]

Identifier: 52143491

GI number: 52143491

Start: 1867676

End: 1868599

Strand: Direct

Name: cobW [H]

Synonym: BCZK1743

Alternate gene names: 52143491

Gene position: 1867676-1868599 (Clockwise)

Preceding gene: 52143492

Following gene: 52143489

Centisome position: 35.23

GC content: 31.49

Gene sequence:

>924_bases
ATGAATAAAGTAGAAATTCATATATTAGGTGGCTTTTTAGGTAGTGGAAAATCAACATTATTACAAAATTTATTGTTAGC
AGAAAAAAAGAAGAATAGAAAAGTTGCAGTATTGATGAATGAAATTGGTGAATACTCGGTAGATACCGATATTATTGGAA
AAGAGAATGTTTTAAGGGAACTTCTTAAGGGGTGTATTTGTTGTACGTTAAAAGAAGAGCTTGAAATACAATTACATTCG
TTATATCAGCAAGAAAGACCAGATGTCATTTATATAGAAACGACAGGTGTTGCGCATCCAATTGAAGTGTTAGATGCATG
TGTATCACCAATTTTAGCACCTTTCTTAGAAGTGAAATCAATAGTAGTCGTTTTAGATGCAGTAAGGTGGTTAAATCGAA
GTATATTAAGTGCAAATGTTCAGCAATTATTATATGAGCAATTGAAGTTTGGTAGCCACATTTTAATTAATAAATCAGAT
TTACTAACATTTGCGGATAAGAACAAAGTAATTGAAGAAGTGAAAGCAATAAATAATCATGCTAAATTGTTTGAAACAGA
ATATTGTAATATATCTTTAGAAGACATAGAAGAAGCTGAATTTACGAATGATGGGAAACAAGAAACACTACATGTAAAAC
AGCATTTACATATACAAACAATGACATATCAATTTACGAAATCGATTGAGCAAGATAATTTATATGAATGGCTTTCAAAT
TTACCAGATAGTATTTATCGTGTAAAAGGATTTGTGAAATTCCATGGAGATAAATACCCGCACCTATTCCAATATTCGTT
TGGCGTACCAACTTTACTGGAACAAGACTTCGGTTTCCCGACGAACTTGGTAGTGATAGGGGAAGGGCTAGATAAGAAAC
AATTAGCTGAAGGGTTAGAGAAAGTAGAACTTAATTCTAATTAA

Upstream 100 bases:

>100_bases
TATATTTACAAATGGTCATTCTTTTAATAAAATGATAAATATAAATCGTAATTATTACGCTTTGAAAACGTTTGAAATAA
AGAAATGGATGGTCGATTAA

Downstream 100 bases:

>100_bases
CATTAAAGGGAGTTGCCCCATAAGTTGATGAAAACGACTTATGGGGCAGTCCTTTTATTTTTTATGAATAAGCATATAGA
TACTTGTATTCATTTTAAAT

Product: GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHS
LYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKSIVVVLDAVRWLNRSILSANVQQLLYEQLKFGSHILINKSD
LLTFADKNKVIEEVKAINNHAKLFETEYCNISLEDIEEAEFTNDGKQETLHVKQHLHIQTMTYQFTKSIEQDNLYEWLSN
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLEKVELNSN

Sequences:

>Translated_307_residues
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHS
LYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKSIVVVLDAVRWLNRSILSANVQQLLYEQLKFGSHILINKSD
LLTFADKNKVIEEVKAINNHAKLFETEYCNISLEDIEEAEFTNDGKQETLHVKQHLHIQTMTYQFTKSIEQDNLYEWLSN
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLEKVELNSN
>Mature_307_residues
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHS
LYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKSIVVVLDAVRWLNRSILSANVQQLLYEQLKFGSHILINKSD
LLTFADKNKVIEEVKAINNHAKLFETEYCNISLEDIEEAEFTNDGKQETLHVKQHLHIQTMTYQFTKSIEQDNLYEWLSN
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLEKVELNSN

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=334, Percent_Identity=26.6467065868263, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI33469141, Length=334, Percent_Identity=26.6467065868263, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI148727351, Length=334, Percent_Identity=26.9461077844311, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI223941779, Length=319, Percent_Identity=26.9592476489028, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI146231952, Length=337, Percent_Identity=27.0029673590504, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI223941776, Length=323, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788499, Length=161, Percent_Identity=34.1614906832298, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082430, Length=302, Percent_Identity=26.8211920529801, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324356, Length=226, Percent_Identity=26.1061946902655, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 34962; Mature: 34962

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRE
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCHHHHHHH
LLKGCICCTLKEELEIQLHSLYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
IVVVLDAVRWLNRSILSANVQQLLYEQLKFGSHILINKSDLLTFADKNKVIEEVKAINNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHEEEHHHHHHHHHHHHHHHH
AKLFETEYCNISLEDIEEAEFTNDGKQETLHVKQHLHIQTMTYQFTKSIEQDNLYEWLSN
HHHEEHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHEEHHHHHHHHHHHCCCCHHHHHHHH
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLE
CCHHHHHHHHHEEECCCCCCEEEEECCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHH
KVELNSN
HHCCCCC
>Mature Secondary Structure
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRE
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCHHHHHHH
LLKGCICCTLKEELEIQLHSLYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
IVVVLDAVRWLNRSILSANVQQLLYEQLKFGSHILINKSDLLTFADKNKVIEEVKAINNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHEEEHHHHHHHHHHHHHHHH
AKLFETEYCNISLEDIEEAEFTNDGKQETLHVKQHLHIQTMTYQFTKSIEQDNLYEWLSN
HHHEEHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHEEHHHHHHHHHHHCCCCHHHHHHHH
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLE
CCHHHHHHHHHEEECCCCCCEEEEECCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHH
KVELNSN
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]