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The map label for this gene is yccK [H]

Identifier: 52143418

GI number: 52143418

Start: 1941999

End: 1942934

Strand: Direct

Name: yccK [H]

Synonym: BCZK1815

Alternate gene names: 52143418

Gene position: 1941999-1942934 (Clockwise)

Preceding gene: 52143422

Following gene: 52143419

Centisome position: 36.64

GC content: 34.62

Gene sequence:

>936_bases
ATGAAGTATACAAAATTGCAAAAGGCAGGACTACATATTTCAAAATTGGGGTTAGGAACAAACGCTGTAGGGGGACATAA
TTTATATGCTGATGTGAATGAGGGAGAAGGAAAACAATTAATAGAAGAAGCTATGGAGCAAGGGATTACATTTTTTGATA
CAGCAGATTCATACGGTTTCGGCAGATCAGAAGAATTGGTAGGGGAAGTATTGAAAGGAAAACGTCACGAAGTTGTACTT
GCTACAAAAGGTGGAATACAGCCGCTATTAAATGGAGAGGTGTATATAAATAATGAACGAAACTATTTAAGAAATGCTGT
GGAAAATAGCTTACGAAGATTACAAACTGATTATATTGATTTATATTATTTACATTTTACAAATCCAGAAACAAGTTATA
TAGATTCAATTGGAGAACTTACTCGCCTAAAAGAAGAAGGGAAAATTCGTTCAATTGGAATATCTAACGTAAACGTAGAG
CAATTAAAAGAAGCGAATCAGCACGGACACATAGATGTTGTACAATCACCGTATAATATGTTGGATCGTACTGCAGGGGA
AGAACTTTTGCCATATTGTATAGAATCAGGTATTTCATTTATCCCTTACGGGCCTCTTGCTTTTGGGGTATTAGGCGGTA
AATATACAGAAGATTTTAAATTGAACGAAGGAGACTGGCGTCAAAGTGTAAATCTATTTGAAGAAAATACATATAAGAGT
AACTTTAAAAAAGTTGAGAAGTTAAAAGGCGTAGCTAAAGAAGAGGCTGTCGAAGTATCGCATTTAGCATTAGCATGGCT
ATTAAATAAAAAAGGAATTGATACTGTTATTCCTGGTGGGAAAAGAGCGGAGCAAATAAGAGAAAGTGTAAGAGCTGTGG
AAGTTTCATTGAATGAAAATGTCATGAAAGAGATTGAATCTATTTTAGAAGATTAG

Upstream 100 bases:

>100_bases
CCTGCTCGTATAAGTTAATATATTTGCACTATAACATATAAAGTGGTATATTTCTATTGTTCGAATATATTCGAACAATA
GAAATATAGGGGGAGAAAAA

Downstream 100 bases:

>100_bases
TTGAAGGAGGGATAGTTCCCTTTTTTATATAAAAGGAGAAGGTTTAAATGAAAAGAGTACTAGCTGTATTCTTTACAATC
ATGTTTATGATCGGTACAGA

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEGEGKQLIEEAMEQGITFFDTADSYGFGRSEELVGEVLKGKRHEVVL
ATKGGIQPLLNGEVYINNERNYLRNAVENSLRRLQTDYIDLYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVE
QLKEANQHGHIDVVQSPYNMLDRTAGEELLPYCIESGISFIPYGPLAFGVLGGKYTEDFKLNEGDWRQSVNLFEENTYKS
NFKKVEKLKGVAKEEAVEVSHLALAWLLNKKGIDTVIPGGKRAEQIRESVRAVEVSLNENVMKEIESILED

Sequences:

>Translated_311_residues
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEGEGKQLIEEAMEQGITFFDTADSYGFGRSEELVGEVLKGKRHEVVL
ATKGGIQPLLNGEVYINNERNYLRNAVENSLRRLQTDYIDLYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVE
QLKEANQHGHIDVVQSPYNMLDRTAGEELLPYCIESGISFIPYGPLAFGVLGGKYTEDFKLNEGDWRQSVNLFEENTYKS
NFKKVEKLKGVAKEEAVEVSHLALAWLLNKKGIDTVIPGGKRAEQIRESVRAVEVSLNENVMKEIESILED
>Mature_311_residues
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEGEGKQLIEEAMEQGITFFDTADSYGFGRSEELVGEVLKGKRHEVVL
ATKGGIQPLLNGEVYINNERNYLRNAVENSLRRLQTDYIDLYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVE
QLKEANQHGHIDVVQSPYNMLDRTAGEELLPYCIESGISFIPYGPLAFGVLGGKYTEDFKLNEGDWRQSVNLFEENTYKS
NFKKVEKLKGVAKEEAVEVSHLALAWLLNKKGIDTVIPGGKRAEQIRESVRAVEVSLNENVMKEIESILED

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=330, Percent_Identity=28.7878787878788, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI4504825, Length=328, Percent_Identity=28.6585365853659, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI27436964, Length=332, Percent_Identity=28.6144578313253, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI27436962, Length=332, Percent_Identity=28.3132530120482, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI27436966, Length=332, Percent_Identity=28.0120481927711, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI27436971, Length=330, Percent_Identity=28.1818181818182, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI41327764, Length=278, Percent_Identity=30.5755395683453, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI223718702, Length=278, Percent_Identity=28.4172661870504, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI41152114, Length=278, Percent_Identity=29.136690647482, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1788070, Length=327, Percent_Identity=34.2507645259939, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI87081735, Length=319, Percent_Identity=33.8557993730408, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=27.3255813953488, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=28.1818181818182, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788081, Length=261, Percent_Identity=26.0536398467433, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787674, Length=303, Percent_Identity=24.0924092409241, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87082198, Length=127, Percent_Identity=33.8582677165354, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI48994888, Length=269, Percent_Identity=25.6505576208178, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17561298, Length=318, Percent_Identity=24.8427672955975, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI212645785, Length=329, Percent_Identity=24.0121580547112, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564128, Length=326, Percent_Identity=23.9263803680982, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71998625, Length=211, Percent_Identity=29.8578199052133, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=334, Percent_Identity=27.5449101796407, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323998, Length=325, Percent_Identity=25.8461538461538, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=293, Percent_Identity=26.962457337884, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=321, Percent_Identity=26.1682242990654, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=222, Percent_Identity=25.6756756756757, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640980, Length=350, Percent_Identity=24, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI45549126, Length=350, Percent_Identity=24, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646159, Length=225, Percent_Identity=32, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24646155, Length=310, Percent_Identity=28.3870967741935, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34874; Mature: 34874

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEGEGKQLIEEAMEQGITFFDTADSYGF
CCCCHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCC
GRSEELVGEVLKGKRHEVVLATKGGIQPLLNGEVYINNERNYLRNAVENSLRRLQTDYID
CCCHHHHHHHHCCCCCEEEEEECCCCCEEECCEEEECCCHHHHHHHHHHHHHHHHHCCEE
LYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVEQLKEANQHGHIDVVQSPYNM
EEEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCCCCCCEEEECCCHHH
LDRTAGEELLPYCIESGISFIPYGPLAFGVLGGKYTEDFKLNEGDWRQSVNLFEENTYKS
HHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NFKKVEKLKGVAKEEAVEVSHLALAWLLNKKGIDTVIPGGKRAEQIRESVRAVEVSLNEN
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
VMKEIESILED
HHHHHHHHHCC
>Mature Secondary Structure
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEGEGKQLIEEAMEQGITFFDTADSYGF
CCCCHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCC
GRSEELVGEVLKGKRHEVVLATKGGIQPLLNGEVYINNERNYLRNAVENSLRRLQTDYID
CCCHHHHHHHHCCCCCEEEEEECCCCCEEECCEEEECCCHHHHHHHHHHHHHHHHHCCEE
LYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVEQLKEANQHGHIDVVQSPYNM
EEEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCCCCCCEEEECCCHHH
LDRTAGEELLPYCIESGISFIPYGPLAFGVLGGKYTEDFKLNEGDWRQSVNLFEENTYKS
HHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NFKKVEKLKGVAKEEAVEVSHLALAWLLNKKGIDTVIPGGKRAEQIRESVRAVEVSLNEN
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
VMKEIESILED
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]