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The map label for this gene is yjiA [H]

Identifier: 52143402

GI number: 52143402

Start: 1958493

End: 1959452

Strand: Direct

Name: yjiA [H]

Synonym: BCZK1833

Alternate gene names: 52143402

Gene position: 1958493-1959452 (Clockwise)

Preceding gene: 52143403

Following gene: 52143399

Centisome position: 36.95

GC content: 33.54

Gene sequence:

>960_bases
ATGTACGAAATGATTCCAGTAACAATATTAACTGGTTTTCTTGGATCTGGGAAAACAACATTATTAAATCGTATTTTAAC
AGAGAATCACGGTAAGAAATTGGCGGTAATTGTAAATGAAATAGGGCAAATTGGCATTGATAATCAGTTGATTATGAATG
TTGAAGAAGAAATTATGGAAATGACAAACGGTTGTTTATGCTGTACTGTACGGGAAGATTTACTCGTTGCGTTAAAACAA
TTACTGGACGTAAAAGCAGAAGGTAAAATGGATTTTGATGGATTAGTAATTGAAACAACTGGCCTTGCAAATCCAGGTCC
AATTATTCAAACATTCTTTTTAGATCCTGTAATTCAATCTGCATATCAAATTAACGGTGTTGTAACAGTAGTAGATAGTT
ATCATATACATAAACATTTTGAAAAAGGACTAGAAGCAAAAGAACAAATTGCATTTGCCGATGTTGTATTAGTGAATAAG
TTAGATTTAATTGAAGAGAGCGAAAAAGACCATCTCTTACATGAATTGCAAGGAATAAATCCGACTGCAAAGTTAATTCA
GTCGACTCACTGTGATGTAGATATTCCATCGTTACTAAAAATTCAAACGTTTAAAACGAAAGATACGTTACAAATCTATC
CTCATAAAGAGCATAATCATCTAGAAGGTGTAAAATCGTTTGTACTACGTGAAGAGCGTCCGTTAGATTTACAAAAACTA
AATGAGTGGATGTCAGCTGTCGTTCAAGAACTAGGAGAATACTTATATCGCTACAAAGGGATTTTATCGATTGATGGAGT
GGATAAACGTATCGTTTTTCAAGGTGTACATACGTTATTTGCTGCTTCGTATGATAGAGAGTGGCAAGAGGGTGAAGATC
GAGTAAGTGAAGTTGTTTTTATCGGAAAAGATATTAATAAAGAATGGTTCCAAGAACATTTTGAGGAGTGTGTGAAATAA

Upstream 100 bases:

>100_bases
TTATTATATAGTTAGAGGGGCGTACAAACAATAAATATGTTTTGCTACAAAAACGATTATTTCTATATGTTATAATGTAA
AAACATATAGCTATAAGGAG

Downstream 100 bases:

>100_bases
GTCTGCGTTTACTGCAGGCTTATTTTTTGGACTTAACTAAGTGTTTTGTAGAAAAATGATAGATTGCCAAAAATGAAGGA
TTAAAAAAGCCTGTTTTCAC

Product: cobalamin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MYEMIPVTILTGFLGSGKTTLLNRILTENHGKKLAVIVNEIGQIGIDNQLIMNVEEEIMEMTNGCLCCTVREDLLVALKQ
LLDVKAEGKMDFDGLVIETTGLANPGPIIQTFFLDPVIQSAYQINGVVTVVDSYHIHKHFEKGLEAKEQIAFADVVLVNK
LDLIEESEKDHLLHELQGINPTAKLIQSTHCDVDIPSLLKIQTFKTKDTLQIYPHKEHNHLEGVKSFVLREERPLDLQKL
NEWMSAVVQELGEYLYRYKGILSIDGVDKRIVFQGVHTLFAASYDREWQEGEDRVSEVVFIGKDINKEWFQEHFEECVK

Sequences:

>Translated_319_residues
MYEMIPVTILTGFLGSGKTTLLNRILTENHGKKLAVIVNEIGQIGIDNQLIMNVEEEIMEMTNGCLCCTVREDLLVALKQ
LLDVKAEGKMDFDGLVIETTGLANPGPIIQTFFLDPVIQSAYQINGVVTVVDSYHIHKHFEKGLEAKEQIAFADVVLVNK
LDLIEESEKDHLLHELQGINPTAKLIQSTHCDVDIPSLLKIQTFKTKDTLQIYPHKEHNHLEGVKSFVLREERPLDLQKL
NEWMSAVVQELGEYLYRYKGILSIDGVDKRIVFQGVHTLFAASYDREWQEGEDRVSEVVFIGKDINKEWFQEHFEECVK
>Mature_319_residues
MYEMIPVTILTGFLGSGKTTLLNRILTENHGKKLAVIVNEIGQIGIDNQLIMNVEEEIMEMTNGCLCCTVREDLLVALKQ
LLDVKAEGKMDFDGLVIETTGLANPGPIIQTFFLDPVIQSAYQINGVVTVVDSYHIHKHFEKGLEAKEQIAFADVVLVNK
LDLIEESEKDHLLHELQGINPTAKLIQSTHCDVDIPSLLKIQTFKTKDTLQIYPHKEHNHLEGVKSFVLREERPLDLQKL
NEWMSAVVQELGEYLYRYKGILSIDGVDKRIVFQGVHTLFAASYDREWQEGEDRVSEVVFIGKDINKEWFQEHFEECVK

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI148727351, Length=343, Percent_Identity=33.5276967930029, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI33469141, Length=343, Percent_Identity=33.2361516034985, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI126722884, Length=343, Percent_Identity=33.2361516034985, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI146231952, Length=339, Percent_Identity=33.0383480825959, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI223941779, Length=332, Percent_Identity=32.5301204819277, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI223941776, Length=333, Percent_Identity=31.8318318318318, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI119120938, Length=320, Percent_Identity=32.1875, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI310124603, Length=227, Percent_Identity=25.5506607929515, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI87082430, Length=318, Percent_Identity=40.5660377358491, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1788499, Length=193, Percent_Identity=32.1243523316062, Blast_Score=88, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324356, Length=361, Percent_Identity=30.4709141274238, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 36334; Mature: 36334

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEMIPVTILTGFLGSGKTTLLNRILTENHGKKLAVIVNEIGQIGIDNQLIMNVEEEIME
CCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHH
MTNGCLCCTVREDLLVALKQLLDVKAEGKMDFDGLVIETTGLANPGPIIQTFFLDPVIQS
HHCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
AYQINGVVTVVDSYHIHKHFEKGLEAKEQIAFADVVLVNKLDLIEESEKDHLLHELQGIN
HHHHCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
PTAKLIQSTHCDVDIPSLLKIQTFKTKDTLQIYPHKEHNHLEGVKSFVLREERPLDLQKL
HHHHHHHHCCCCCCCCHHHEEEEECCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCHHHH
NEWMSAVVQELGEYLYRYKGILSIDGVDKRIVFQGVHTLFAASYDREWQEGEDRVSEVVF
HHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEE
IGKDINKEWFQEHFEECVK
ECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MYEMIPVTILTGFLGSGKTTLLNRILTENHGKKLAVIVNEIGQIGIDNQLIMNVEEEIME
CCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHH
MTNGCLCCTVREDLLVALKQLLDVKAEGKMDFDGLVIETTGLANPGPIIQTFFLDPVIQS
HHCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
AYQINGVVTVVDSYHIHKHFEKGLEAKEQIAFADVVLVNKLDLIEESEKDHLLHELQGIN
HHHHCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
PTAKLIQSTHCDVDIPSLLKIQTFKTKDTLQIYPHKEHNHLEGVKSFVLREERPLDLQKL
HHHHHHHHCCCCCCCCHHHEEEEECCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCHHHH
NEWMSAVVQELGEYLYRYKGILSIDGVDKRIVFQGVHTLFAASYDREWQEGEDRVSEVVF
HHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEE
IGKDINKEWFQEHFEECVK
ECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]