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The map label for this gene is namA [H]

Identifier: 52143393

GI number: 52143393

Start: 1969902

End: 1970939

Strand: Reverse

Name: namA [H]

Synonym: BCZK1843

Alternate gene names: 52143393

Gene position: 1970939-1969902 (Counterclockwise)

Preceding gene: 52143384

Following gene: 52143391

Centisome position: 37.18

GC content: 39.21

Gene sequence:

>1038_bases
ATGAATTCCGAACTTTTTTCACCTTATACAATTAAGGACGTTACACTAAAAAACCGGATTGTTATGTCACCTATGTGCAT
GTATTCATCAGAAAACGAGGATGGCCAAGTAACGAATTTCCATCTCGTTCATTATGGAACAAGAGCTGCCGGTCAAGTTG
GTTTAGTAATGATTGAAGCAACAGCCGTGTTACCTGAAGGTCGAATTTCAAATAAAGACTTAGGCATTTGGGATGACAGT
CTAATTGAAGGCTTACATAAAACGACAACTTTTATACATGATAACGGTGCAAAAGCTGCCATTCAACTCGCTCATGCTGG
AAGAAAAGCTGAATTAGAAACGGATGCTCTCGCTCCATCCGCCATTCCGTTTAATGAAACTATGAAAACACCAGTAGAAA
TGAGTAAACACCAAATTAAAGATACTATATTAGCTTTTCAGCAGGCTGCAATACGATCAAAACAAGCTGGATTTGACGTT
ATTGAAATACATGGCGCCCACGGTTATCTCATTAATGAATTTCTTTCTCCGCTTTCCAATAAGCGTACTGATGAATATGG
CGGTTCACCTGAAAACCGCTATCGTTTCTTACGCGAAATCATTGACTCGATAAATGAAGTTTGGAACGGACCGTTATTTG
TTCGTATTTCAGCAAATGATTATCACCCTGACGGGTTAACGGTTCAAGATTACGTTCAGTATACAAAATGGATGAAAGAA
CAAGGAGTAGATTTAATCGATTGTAGTTCTGGGGCTGTTGTACCTGCACGCATCGATGTTTATCCTGGATATCAAGTACA
ATACGCTAAACATATTAAAGAACATGCTAACATTGCAACTGGTGCTGTTGGATTGATTACGACCGGGGCACAAGCAGAGC
AAATTTTAAACAATAACGAAGCAGATTTAATTTTTATCGGACGTGAGTTACTTCGCAATCCTTACTTCCCAAGAATAGCC
GCCAATGAACTTGGCTTTGAGTTAGAAGAACCGCATCAATACGAGCGAGCGCCTGGGAAAATTAGTACAAATAAATAA

Upstream 100 bases:

>100_bases
TGTAACACGAATAGACAAAATTTTTCGTATAAGCGTTTTATTAGAGAAACGAAGAAGAGAATGATACAATGTAAGAAAAT
TCAATCTAGGAGGCTATTGG

Downstream 100 bases:

>100_bases
AACCGAGAAGCTTTTCTTCTCGGTTTTATTTATTCTATCGTTGTAATTTCATTCGAATTGTAAATGTGGATACCTGATTC
TTCTCGCAATGCAGTTATAT

Product: NADPH dehydrogenase NamA

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNSELFSPYTIKDVTLKNRIVMSPMCMYSSENEDGQVTNFHLVHYGTRAAGQVGLVMIEATAVLPEGRISNKDLGIWDDS
LIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELETDALAPSAIPFNETMKTPVEMSKHQIKDTILAFQQAAIRSKQAGFDV
IEIHGAHGYLINEFLSPLSNKRTDEYGGSPENRYRFLREIIDSINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNEADLIFIGRELLRNPYFPRIA
ANELGFELEEPHQYERAPGKISTNK

Sequences:

>Translated_345_residues
MNSELFSPYTIKDVTLKNRIVMSPMCMYSSENEDGQVTNFHLVHYGTRAAGQVGLVMIEATAVLPEGRISNKDLGIWDDS
LIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELETDALAPSAIPFNETMKTPVEMSKHQIKDTILAFQQAAIRSKQAGFDV
IEIHGAHGYLINEFLSPLSNKRTDEYGGSPENRYRFLREIIDSINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNEADLIFIGRELLRNPYFPRIA
ANELGFELEEPHQYERAPGKISTNK
>Mature_345_residues
MNSELFSPYTIKDVTLKNRIVMSPMCMYSSENEDGQVTNFHLVHYGTRAAGQVGLVMIEATAVLPEGRISNKDLGIWDDS
LIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELETDALAPSAIPFNETMKTPVEMSKHQIKDTILAFQQAAIRSKQAGFDV
IEIHGAHGYLINEFLSPLSNKRTDEYGGSPENRYRFLREIIDSINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNEADLIFIGRELLRNPYFPRIA
ANELGFELEEPHQYERAPGKISTNK

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=240, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1789463, Length=317, Percent_Identity=30.2839116719243, Blast_Score=118, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17559802, Length=261, Percent_Identity=31.0344827586207, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI72001454, Length=251, Percent_Identity=31.8725099601594, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=181, Percent_Identity=32.0441988950276, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17540738, Length=257, Percent_Identity=29.9610894941634, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=333, Percent_Identity=28.8288288288288, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17559804, Length=174, Percent_Identity=36.2068965517241, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17564188, Length=174, Percent_Identity=33.9080459770115, Blast_Score=98, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6325086, Length=223, Percent_Identity=33.6322869955157, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6321973, Length=220, Percent_Identity=33.6363636363636, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 38463; Mature: 38463

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSELFSPYTIKDVTLKNRIVMSPMCMYSSENEDGQVTNFHLVHYGTRAAGQVGLVMIEA
CCCCCCCCEEEEEEEECCEEEECHHHCCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEEE
TAVLPEGRISNKDLGIWDDSLIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELETDALAPS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCEEEEEHHCCCCCCCCHHHCCCC
AIPFNETMKTPVEMSKHQIKDTILAFQQAAIRSKQAGFDVIEIHGAHGYLINEFLSPLSN
CCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHC
KRTDEYGGSPENRYRFLREIIDSINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNE
CCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCHHCCCCEEEECCHHHHHHHCCCC
ADLIFIGRELLRNPYFPRIAANELGFELEEPHQYERAPGKISTNK
CCEEEECHHHHCCCCCCCEEHHHCCCCCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MNSELFSPYTIKDVTLKNRIVMSPMCMYSSENEDGQVTNFHLVHYGTRAAGQVGLVMIEA
CCCCCCCCEEEEEEEECCEEEECHHHCCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEEE
TAVLPEGRISNKDLGIWDDSLIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELETDALAPS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCEEEEEHHCCCCCCCCHHHCCCC
AIPFNETMKTPVEMSKHQIKDTILAFQQAAIRSKQAGFDVIEIHGAHGYLINEFLSPLSN
CCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHC
KRTDEYGGSPENRYRFLREIIDSINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNE
CCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCHHCCCCEEEECCHHHHHHHCCCC
ADLIFIGRELLRNPYFPRIAANELGFELEEPHQYERAPGKISTNK
CCEEEECHHHHCCCCCCCEEHHHCCCCCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA