Click here to switch to the map view.

The map label for this gene is gntR [H]

Identifier: 52143346

GI number: 52143346

Start: 2010946

End: 2012346

Strand: Reverse

Name: gntR [H]

Synonym: BCZK1890

Alternate gene names: 52143346

Gene position: 2012346-2010946 (Counterclockwise)

Preceding gene: 52143342

Following gene: 52143349

Centisome position: 37.96

GC content: 35.4

Gene sequence:

>1401_bases
ATGGATTTGAATATTCCTTTAGTGTTACAAAATAAAACACCTATTTACTTACAAATTTACGAATATATGAAACGAGAAAT
CTCTCATGGATCACTACGTGCTGGTACACGCCTTCCTTCTCACAGAAATTTAGCTATGCAACTTAATGTAAGCCGTATTA
CAGTTGAATCCGCTTATCAACAATTACTAGCTGAAGGTTATGTAGAAAGCAAACCGAAACGCGGAATTTTTGTTGCGGAA
GTTGATATTGATGTCATTCAAAAGAAACAACAAATTGCGTCAAACAGTGCTAACAATAAAGAAAAAGAACAATATGATTA
TGATTGTAGTCAAGGACTTATTGATCAAAAAGCTTTTCCGATAACAAACTGGAAAAGAGCATTACACGAAACTTTATTTC
AGTATGAAAATGAATTATTTGCTAAAGAGGATCCACAAGGTGAGCTCGTTCTACGAGAACATATTTCAAAGTATTTATAT
CATGCTCGCGGGGTACATTCTTCACCTGATCAAATTATTATTGGCGCAGGTACGCAGCCTCTTCTTTGGCTACTACTTCA
ACTACTTGGTTCAAAAAAAGAATATGGAATCGAAAATCCTGGATTTCACCGTATACCTGCAATGATTCAAAGTTGTGGCC
TTCCTGTTCACCCGATCCCTTTAGACGATAAAGGGATTCATATTTCCGCTTTACGTGAATCGGGGGCCAATGTAGCATAT
GTCACTCCATCTCACCAATTTCCACTCGGAATCATTATGCCGTTATCTAGAAGACTCGAGTTATTAAAATGGACGAATGA
TTGTAATGGTTATATTATTGAAGATGATTACGATGGAGAATTTCGCTATATTGGAAAACCTATTCCTTCTTTACAAGGGC
TAGATTCAAATGAACGTGTTATTTATATGGGAACTTTCTCGAAATCTTTTTTACCTTCTTTACGAATGGGATATATCGTT
TTACCACCTCATCTTTTAAAAGTCTATAAAGAACTTGGTGGTATGTTTAAACAAACGGTTTCTACAATGCAACAGCTTAC
CTTTGCTACCTTTATTCAAAGTGGTGATTGGGAACGTCATATTAATCGAAGTCGTACATTATATAAAAGAAAACATATTT
CTTTAATTAAATCTATTTCATACGAAATGGGAAATAACGTTCATATACTCGGCGAACAATCCGGACTTCATATTGTACTT
CACGTTCATAATGGTATGAACGAACGAGAACTTATTCATGCAGCTGCAAAACAACGCATTAAGTTATACCCTCTATCGAC
ATACGATTCTGTTCATAATGTAAGGGAGGAATCATATGTATTACTCGGTTTTGGCAGTATTCGAGAGGAATGTATTGAAA
CCGTTGTCAAATTACTGAAAAAAGCGTGGTTCCCTAAATAA

Upstream 100 bases:

>100_bases
TTACGGGCAGTTGATTCCCACCTAACTTCTTTGCTTCCGCTGAATTTTGAGGTGAGGGTCTTACTGCCCGTTAATGCGGG
ATTAAAAGGAGCGTCTATAA

Downstream 100 bases:

>100_bases
AAATAGCTCCACGCAAGTTATACTTACGTGGAGCTATTTTTATGCACTATTTTTCTGATCTCATTGCCCTTCCCGGACGT
TTGACACCAGTTGTTTCTGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MDLNIPLVLQNKTPIYLQIYEYMKREISHGSLRAGTRLPSHRNLAMQLNVSRITVESAYQQLLAEGYVESKPKRGIFVAE
VDIDVIQKKQQIASNSANNKEKEQYDYDCSQGLIDQKAFPITNWKRALHETLFQYENELFAKEDPQGELVLREHISKYLY
HARGVHSSPDQIIIGAGTQPLLWLLLQLLGSKKEYGIENPGFHRIPAMIQSCGLPVHPIPLDDKGIHISALRESGANVAY
VTPSHQFPLGIIMPLSRRLELLKWTNDCNGYIIEDDYDGEFRYIGKPIPSLQGLDSNERVIYMGTFSKSFLPSLRMGYIV
LPPHLLKVYKELGGMFKQTVSTMQQLTFATFIQSGDWERHINRSRTLYKRKHISLIKSISYEMGNNVHILGEQSGLHIVL
HVHNGMNERELIHAAAKQRIKLYPLSTYDSVHNVREESYVLLGFGSIREECIETVVKLLKKAWFPK

Sequences:

>Translated_466_residues
MDLNIPLVLQNKTPIYLQIYEYMKREISHGSLRAGTRLPSHRNLAMQLNVSRITVESAYQQLLAEGYVESKPKRGIFVAE
VDIDVIQKKQQIASNSANNKEKEQYDYDCSQGLIDQKAFPITNWKRALHETLFQYENELFAKEDPQGELVLREHISKYLY
HARGVHSSPDQIIIGAGTQPLLWLLLQLLGSKKEYGIENPGFHRIPAMIQSCGLPVHPIPLDDKGIHISALRESGANVAY
VTPSHQFPLGIIMPLSRRLELLKWTNDCNGYIIEDDYDGEFRYIGKPIPSLQGLDSNERVIYMGTFSKSFLPSLRMGYIV
LPPHLLKVYKELGGMFKQTVSTMQQLTFATFIQSGDWERHINRSRTLYKRKHISLIKSISYEMGNNVHILGEQSGLHIVL
HVHNGMNERELIHAAAKQRIKLYPLSTYDSVHNVREESYVLLGFGSIREECIETVVKLLKKAWFPK
>Mature_466_residues
MDLNIPLVLQNKTPIYLQIYEYMKREISHGSLRAGTRLPSHRNLAMQLNVSRITVESAYQQLLAEGYVESKPKRGIFVAE
VDIDVIQKKQQIASNSANNKEKEQYDYDCSQGLIDQKAFPITNWKRALHETLFQYENELFAKEDPQGELVLREHISKYLY
HARGVHSSPDQIIIGAGTQPLLWLLLQLLGSKKEYGIENPGFHRIPAMIQSCGLPVHPIPLDDKGIHISALRESGANVAY
VTPSHQFPLGIIMPLSRRLELLKWTNDCNGYIIEDDYDGEFRYIGKPIPSLQGLDSNERVIYMGTFSKSFLPSLRMGYIV
LPPHLLKVYKELGGMFKQTVSTMQQLTFATFIQSGDWERHINRSRTLYKRKHISLIKSISYEMGNNVHILGEQSGLHIVL
HVHNGMNERELIHAAAKQRIKLYPLSTYDSVHNVREESYVLLGFGSIREECIETVVKLLKKAWFPK

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787710, Length=439, Percent_Identity=26.6514806378132, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1790797, Length=385, Percent_Identity=26.7532467532467, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53368; Mature: 53368

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNIPLVLQNKTPIYLQIYEYMKREISHGSLRAGTRLPSHRNLAMQLNVSRITVESAYQ
CCCCCEEEECCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHEEEHHHHHH
QLLAEGYVESKPKRGIFVAEVDIDVIQKKQQIASNSANNKEKEQYDYDCSQGLIDQKAFP
HHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCHHHHCCCCHHCCCCCCCCCC
ITNWKRALHETLFQYENELFAKEDPQGELVLREHISKYLYHARGVHSSPDQIIIGAGTQP
CHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHH
LLWLLLQLLGSKKEYGIENPGFHRIPAMIQSCGLPVHPIPLDDKGIHISALRESGANVAY
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEE
VTPSHQFPLGIIMPLSRRLELLKWTNDCNGYIIEDDYDGEFRYIGKPIPSLQGLDSNERV
ECCCCCCCCHHHHCHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCEE
IYMGTFSKSFLPSLRMGYIVLPPHLLKVYKELGGMFKQTVSTMQQLTFATFIQSGDWERH
EEEECCCHHHCCHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
INRSRTLYKRKHISLIKSISYEMGNNVHILGEQSGLHIVLHVHNGMNERELIHAAAKQRI
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHCCE
KLYPLSTYDSVHNVREESYVLLGFGSIREECIETVVKLLKKAWFPK
EEEECCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLNIPLVLQNKTPIYLQIYEYMKREISHGSLRAGTRLPSHRNLAMQLNVSRITVESAYQ
CCCCCEEEECCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHEEEHHHHHH
QLLAEGYVESKPKRGIFVAEVDIDVIQKKQQIASNSANNKEKEQYDYDCSQGLIDQKAFP
HHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCHHHHCCCCHHCCCCCCCCCC
ITNWKRALHETLFQYENELFAKEDPQGELVLREHISKYLYHARGVHSSPDQIIIGAGTQP
CHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHH
LLWLLLQLLGSKKEYGIENPGFHRIPAMIQSCGLPVHPIPLDDKGIHISALRESGANVAY
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEE
VTPSHQFPLGIIMPLSRRLELLKWTNDCNGYIIEDDYDGEFRYIGKPIPSLQGLDSNERV
ECCCCCCCCHHHHCHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCEE
IYMGTFSKSFLPSLRMGYIVLPPHLLKVYKELGGMFKQTVSTMQQLTFATFIQSGDWERH
EEEECCCHHHCCHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
INRSRTLYKRKHISLIKSISYEMGNNVHILGEQSGLHIVLHVHNGMNERELIHAAAKQRI
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHCCE
KLYPLSTYDSVHNVREESYVLLGFGSIREECIETVVKLLKKAWFPK
EEEECCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]