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The map label for this gene is argS

Identifier: 52143263

GI number: 52143263

Start: 2085128

End: 2086816

Strand: Direct

Name: argS

Synonym: BCZK1974

Alternate gene names: 52143263

Gene position: 2085128-2086816 (Clockwise)

Preceding gene: 52143264

Following gene: 52143262

Centisome position: 39.34

GC content: 35.76

Gene sequence:

>1689_bases
ATGGATTATAAAACGCAGTTTGCGGAAAGTTTATCTAATATTTTTACGAATGAATTAACGCAAAAGCAAATTTTAGATTT
AATTGAAACACCGAAACAAGATGAATTCGGAGATGCTGCATTTCCGTGTTTTTCACTTGCGAAGCAATATAAAAAATCAC
CAGCTATTATCGCAAAGGAAGTTGCAGAGAAATTAAGTGATCCGTTTTTTACGAAAGTAGAGGCTGTTGGTCCTTATGTA
AATGTATTTTTTAATCGTGATACAGTAAGTGATGCAGTATTAAAAACGATTTTAGCGGAGAAAGAAGAGTACGGTCAAAA
TCATTTTGGATGTGAAAAAACGGTCGTTATCGATTATTCCTCTCCTAATATCGCGAAACCTTTTTCAATGGGGCATTTAC
GTTCTACAATGATTGGAAATTCATTGAAACATATCGCTGAAAAATGTGGTTATGAAGTTGTAGGGATTAATTATATTGGG
GATTGGGGAACACAGTTTGGAAAGTTAATTACGGCTTATAAAAAATGGGGAAATGAAGCAGTAGTGAAAGAGGATCCAAT
ACGTGAACTATTTAAGTTATATGTTCAATTCCATGAAGAGATAAAAGACGACGAAGAATTAGAAGAAGAAGGACGTGCTT
GGTTTAAGAAATTAGAAGAAGGTGATGAAGAAGCTGTTGAGCTTTGGAATTGGTTCCGCCACGAATCCTTAAAAGAATTT
TCTCGTATTTATGAACTTCTCGGTGTGGAATTTACTAATTTTCAAGGAGAAGCTTTTTATAATAATTTAATGGAAGACTT
TATTGGGATTTTAGAGGAACATGATTTACTTGAAGAGTCAGAAGGTGCATTAGTCGTTAATTTAGAAGAAGAGGGCATGC
CACCTTGCTTAATTAGAAAATCAGATGGTGCGACGATTTACGCAACGCGTGACTTAACGGCAGCTCTATATCGTCAAAAC
ACATTTGGTTTTGATAAAGCGTTATACGTAGTTGGCCCAGAACAAAGTTTACACTTCAATCAATTCTTCACTGTATTAAA
AAAGCTCGGCTACACTTGGGTTGATGGCATGGAACATGTACCGTTTGGGTTCATTTTAAAAGACGGTAAGAAAATGTCCA
CACGTAAAGGAAGAGTTATTTTACTTGAAGAAGTACTTGAGGAAGCAATCGAACTTGCAAAACAAAATATTGAAGAGAAA
AATCCAAACTTGAAACAGAAAGAAGAAGTAGCAAAGCAAGTCGGCGCTGGCGCAGTCATCTTCCACGATTTAAAAAATGA
GCGTATGCACAATATTGAATTCTCATTAGAAAATATGCTGAAATTCGAAGGGGAAACAGGCCCGTACGTACAATACACAC
ATGCACGTGCTTGCTCTATTTTAAGAAAAGAAAGTGTAGAATTTGAAACGTGTACGTTTACCTTAAAAGATGATTATAGT
TGGAATATCGTAAAATTACTAAACAAATTCCCAGAAGTAATTGAAGCAGCATGTAACAAAAATGAGCCATCGGTTATTTC
GAAATACGTATTAGATGTGGCACAATCGTTTAATAAATATTATGGAAATGTGCGTATATTAGATGAAAACGCCGAAAAAG
ACAGTAGACTGGCATTAGTGTATGCTGTGACGGTTGTATTAAAAGAGGGGTTACGTTTACTTGGGGTGGAGGCACCTGAG
GAGATGTAA

Upstream 100 bases:

>100_bases
AGTGGTTCGTAATGAACAACAAGGGTGGTACCACGGGTTCAAACTCGTCTCTTTTTTAGAGACGAGTTTTTTGTGTTTTA
AAAAATAAGGAGGTTGTAGT

Downstream 100 bases:

>100_bases
CATAAAAAGGTGTATGTATCATTACAGATATGTATGCCTTTTTTATTTTGTATAGGAACGGTGTAAGCAGTATTTTCATA
TTATCAAAACTATATTTGAA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase 1; ArgRS 1

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MDYKTQFAESLSNIFTNELTQKQILDLIETPKQDEFGDAAFPCFSLAKQYKKSPAIIAKEVAEKLSDPFFTKVEAVGPYV
NVFFNRDTVSDAVLKTILAEKEEYGQNHFGCEKTVVIDYSSPNIAKPFSMGHLRSTMIGNSLKHIAEKCGYEVVGINYIG
DWGTQFGKLITAYKKWGNEAVVKEDPIRELFKLYVQFHEEIKDDEELEEEGRAWFKKLEEGDEEAVELWNWFRHESLKEF
SRIYELLGVEFTNFQGEAFYNNLMEDFIGILEEHDLLEESEGALVVNLEEEGMPPCLIRKSDGATIYATRDLTAALYRQN
TFGFDKALYVVGPEQSLHFNQFFTVLKKLGYTWVDGMEHVPFGFILKDGKKMSTRKGRVILLEEVLEEAIELAKQNIEEK
NPNLKQKEEVAKQVGAGAVIFHDLKNERMHNIEFSLENMLKFEGETGPYVQYTHARACSILRKESVEFETCTFTLKDDYS
WNIVKLLNKFPEVIEAACNKNEPSVISKYVLDVAQSFNKYYGNVRILDENAEKDSRLALVYAVTVVLKEGLRLLGVEAPE
EM

Sequences:

>Translated_562_residues
MDYKTQFAESLSNIFTNELTQKQILDLIETPKQDEFGDAAFPCFSLAKQYKKSPAIIAKEVAEKLSDPFFTKVEAVGPYV
NVFFNRDTVSDAVLKTILAEKEEYGQNHFGCEKTVVIDYSSPNIAKPFSMGHLRSTMIGNSLKHIAEKCGYEVVGINYIG
DWGTQFGKLITAYKKWGNEAVVKEDPIRELFKLYVQFHEEIKDDEELEEEGRAWFKKLEEGDEEAVELWNWFRHESLKEF
SRIYELLGVEFTNFQGEAFYNNLMEDFIGILEEHDLLEESEGALVVNLEEEGMPPCLIRKSDGATIYATRDLTAALYRQN
TFGFDKALYVVGPEQSLHFNQFFTVLKKLGYTWVDGMEHVPFGFILKDGKKMSTRKGRVILLEEVLEEAIELAKQNIEEK
NPNLKQKEEVAKQVGAGAVIFHDLKNERMHNIEFSLENMLKFEGETGPYVQYTHARACSILRKESVEFETCTFTLKDDYS
WNIVKLLNKFPEVIEAACNKNEPSVISKYVLDVAQSFNKYYGNVRILDENAEKDSRLALVYAVTVVLKEGLRLLGVEAPE
EM
>Mature_562_residues
MDYKTQFAESLSNIFTNELTQKQILDLIETPKQDEFGDAAFPCFSLAKQYKKSPAIIAKEVAEKLSDPFFTKVEAVGPYV
NVFFNRDTVSDAVLKTILAEKEEYGQNHFGCEKTVVIDYSSPNIAKPFSMGHLRSTMIGNSLKHIAEKCGYEVVGINYIG
DWGTQFGKLITAYKKWGNEAVVKEDPIRELFKLYVQFHEEIKDDEELEEEGRAWFKKLEEGDEEAVELWNWFRHESLKEF
SRIYELLGVEFTNFQGEAFYNNLMEDFIGILEEHDLLEESEGALVVNLEEEGMPPCLIRKSDGATIYATRDLTAALYRQN
TFGFDKALYVVGPEQSLHFNQFFTVLKKLGYTWVDGMEHVPFGFILKDGKKMSTRKGRVILLEEVLEEAIELAKQNIEEK
NPNLKQKEEVAKQVGAGAVIFHDLKNERMHNIEFSLENMLKFEGETGPYVQYTHARACSILRKESVEFETCTFTLKDDYS
WNIVKLLNKFPEVIEAACNKNEPSVISKYVLDVAQSFNKYYGNVRILDENAEKDSRLALVYAVTVVLKEGLRLLGVEAPE
EM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=512, Percent_Identity=35.9375, Blast_Score=323, Evalue=3e-88,
Organism=Homo sapiens, GI15149476, Length=570, Percent_Identity=28.4210526315789, Blast_Score=221, Evalue=2e-57,
Organism=Escherichia coli, GI1788184, Length=547, Percent_Identity=34.0036563071298, Blast_Score=286, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI71985061, Length=570, Percent_Identity=30.1754385964912, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71985068, Length=546, Percent_Identity=30.4029304029304, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17532153, Length=492, Percent_Identity=29.2682926829268, Blast_Score=193, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6320548, Length=560, Percent_Identity=37.1428571428571, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6321883, Length=560, Percent_Identity=35.3571428571429, Blast_Score=353, Evalue=6e-98,
Organism=Drosophila melanogaster, GI18859963, Length=564, Percent_Identity=29.4326241134752, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI28571570, Length=466, Percent_Identity=31.9742489270386, Blast_Score=223, Evalue=4e-58,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR1_BACCZ (Q63C01)

Other databases:

- EMBL:   CP000001
- RefSeq:   YP_083566.1
- ProteinModelPortal:   Q63C01
- SMR:   Q63C01
- STRING:   Q63C01
- EnsemblBacteria:   EBBACT00000043699
- GeneID:   3026695
- GenomeReviews:   CP000001_GR
- KEGG:   bcz:BCZK1974
- eggNOG:   COG0018
- GeneTree:   EBGT00050000002259
- HOGENOM:   HBG695395
- OMA:   AYKKWGN
- ProtClustDB:   PRK12451
- BioCyc:   BCER288681:BCE33L1974-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 64426; Mature: 64426

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKTQFAESLSNIFTNELTQKQILDLIETPKQDEFGDAAFPCFSLAKQYKKSPAIIAKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
VAEKLSDPFFTKVEAVGPYVNVFFNRDTVSDAVLKTILAEKEEYGQNHFGCEKTVVIDYS
HHHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
SPNIAKPFSMGHLRSTMIGNSLKHIAEKCGYEVVGINYIGDWGTQFGKLITAYKKWGNEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCC
VVKEDPIRELFKLYVQFHEEIKDDEELEEEGRAWFKKLEEGDEEAVELWNWFRHESLKEF
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SRIYELLGVEFTNFQGEAFYNNLMEDFIGILEEHDLLEESEGALVVNLEEEGMPPCLIRK
HHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEE
SDGATIYATRDLTAALYRQNTFGFDKALYVVGPEQSLHFNQFFTVLKKLGYTWVDGMEHV
CCCCEEEEECHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCCC
PFGFILKDGKKMSTRKGRVILLEEVLEEAIELAKQNIEEKNPNLKQKEEVAKQVGAGAVI
CCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEE
FHDLKNERMHNIEFSLENMLKFEGETGPYVQYTHARACSILRKESVEFETCTFTLKDDYS
EEHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCEEEEEEEECCCCC
WNIVKLLNKFPEVIEAACNKNEPSVISKYVLDVAQSFNKYYGNVRILDENAEKDSRLALV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
YAVTVVLKEGLRLLGVEAPEEM
HHHHHHHHHCHHHCCCCCCCCC
>Mature Secondary Structure
MDYKTQFAESLSNIFTNELTQKQILDLIETPKQDEFGDAAFPCFSLAKQYKKSPAIIAKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
VAEKLSDPFFTKVEAVGPYVNVFFNRDTVSDAVLKTILAEKEEYGQNHFGCEKTVVIDYS
HHHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
SPNIAKPFSMGHLRSTMIGNSLKHIAEKCGYEVVGINYIGDWGTQFGKLITAYKKWGNEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCC
VVKEDPIRELFKLYVQFHEEIKDDEELEEEGRAWFKKLEEGDEEAVELWNWFRHESLKEF
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SRIYELLGVEFTNFQGEAFYNNLMEDFIGILEEHDLLEESEGALVVNLEEEGMPPCLIRK
HHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEE
SDGATIYATRDLTAALYRQNTFGFDKALYVVGPEQSLHFNQFFTVLKKLGYTWVDGMEHV
CCCCEEEEECHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCCC
PFGFILKDGKKMSTRKGRVILLEEVLEEAIELAKQNIEEKNPNLKQKEEVAKQVGAGAVI
CCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEE
FHDLKNERMHNIEFSLENMLKFEGETGPYVQYTHARACSILRKESVEFETCTFTLKDDYS
EEHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCEEEEEEEECCCCC
WNIVKLLNKFPEVIEAACNKNEPSVISKYVLDVAQSFNKYYGNVRILDENAEKDSRLALV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
YAVTVVLKEGLRLLGVEAPEEM
HHHHHHHHHCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA