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The map label for this gene is aspC [H]

Identifier: 52143256

GI number: 52143256

Start: 2100163

End: 2101461

Strand: Direct

Name: aspC [H]

Synonym: BCZK1981

Alternate gene names: 52143256

Gene position: 2100163-2101461 (Clockwise)

Preceding gene: 52143257

Following gene: 52143255

Centisome position: 39.62

GC content: 34.72

Gene sequence:

>1299_bases
ATGGAGTCAATAATGAAGCGTTCACTCACAAAAGAATGTACAAAGCAAAGCGGAAAAGTTGTATTACTTCAAGGATGGGT
AAAAAAGATTCGTCATCTTGGAAATGTTAGTTTTTTATTATTACGGGACAGAACAGGGGTAATTCAATGTGTATTAGAAA
ATGAATTCGCTGGATATAAAGTTGATGTAGAGAGTGTCGTCCATGTAATCGGCGAGATAGTCGAAACAACGAAAACAGAA
TTGGGTGTTGAATTACTTGCGCATGAAGTGAAAGTAATAAACGGTGCAGAACAACTTCCATTTGAAATAAATAAAAAGAA
GTTACAAGTTGGCTTAGATCAACTACTTAATGAGCGGGTATTATCATTAAGACATGAGAGAACCGCGGCGATATTTAAAG
TGAAATCTACGTTCGTTCATAGCTTTAGTGAATTCCTTACAGAGAACGATTTCACACGTATATTTACTCCGAAAATTGTT
TCGCAAGGGGCAGAAGGAGGAGCAAATGTTTTTAAGCTTCCATACTTCCAAAAAGAAGCTTATTTAGCACAATCACCACA
GTTTTATAAACAAATGATGGTAGCTGGGGGACTCGAACGTGTTTTTGAAATTGCACCTGTTTATAGGGCGGAACATCACA
ATTCTTCCCGTCATTTAAATGAATATATATCGTTAGACGTAGAGCTTAGCTTTATTCATGATTTTCATGAAGTGATGCAA
TTAGAAACAGATGTTTTACGATATATGTTTCAACAAGTAGCAAAAAACTGTGAGAAAGAACTACAACTATTACAAATAGA
AGTACCTGTTATTACTGAAATACCGAAAATCACATTGTTAGAAGCACAAGAGATCTTGAAAAGTAAGTATTGTAAAGAAT
CTCCTGTAGGGGATTTAGATACAGAAGGTGAAAAGTTACTGGGGAAATATGTGAAGGAAACATATAAGAGTGAATTTGTT
TTTATTACACATTATCCGAAAGAAGCGAGACCGATGTATACAATGCCGAATAACGAGAATTCTTCTATTACTGACTCGTT
TGACTTATTATATAAAGGATTAGAAATAACATCAGGAGCACAGCGAATTCATAATTATGAAATGTTACTAGATTCTTTTA
AAGGAAAAGGATTACATCCCGATAAATTTCAATCGTATTTAAATACATTTCGATACGGTTGTCCCCCGCACGGTGGTTTT
GGAATTGGCTTAGAGAGAATTGTATATAAACTTTTAGAATTATCGAATGTGAGAGAAGCGAGTGCTTTTCCAAGAGATTG
TATGCGTCTTATACCATAA

Upstream 100 bases:

>100_bases
CGGATTTTTGTATTCTTTTAAGGGAGGTGAGTGACCGTGGATGATGACGATGACAACAACAATAACGTAAATAAATATAA
AATTATTGGAGGGAAAAATA

Downstream 100 bases:

>100_bases
CATTAGCACCCTTCTATAGTATAGAAGGGTGCTTTGCATTTCAATAAAAGTGAAAGAGAATAATAATATTTTTTGTGTGA
AAATATGTAAATTATATTAA

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MESIMKRSLTKECTKQSGKVVLLQGWVKKIRHLGNVSFLLLRDRTGVIQCVLENEFAGYKVDVESVVHVIGEIVETTKTE
LGVELLAHEVKVINGAEQLPFEINKKKLQVGLDQLLNERVLSLRHERTAAIFKVKSTFVHSFSEFLTENDFTRIFTPKIV
SQGAEGGANVFKLPYFQKEAYLAQSPQFYKQMMVAGGLERVFEIAPVYRAEHHNSSRHLNEYISLDVELSFIHDFHEVMQ
LETDVLRYMFQQVAKNCEKELQLLQIEVPVITEIPKITLLEAQEILKSKYCKESPVGDLDTEGEKLLGKYVKETYKSEFV
FITHYPKEARPMYTMPNNENSSITDSFDLLYKGLEITSGAQRIHNYEMLLDSFKGKGLHPDKFQSYLNTFRYGCPPHGGF
GIGLERIVYKLLELSNVREASAFPRDCMRLIP

Sequences:

>Translated_432_residues
MESIMKRSLTKECTKQSGKVVLLQGWVKKIRHLGNVSFLLLRDRTGVIQCVLENEFAGYKVDVESVVHVIGEIVETTKTE
LGVELLAHEVKVINGAEQLPFEINKKKLQVGLDQLLNERVLSLRHERTAAIFKVKSTFVHSFSEFLTENDFTRIFTPKIV
SQGAEGGANVFKLPYFQKEAYLAQSPQFYKQMMVAGGLERVFEIAPVYRAEHHNSSRHLNEYISLDVELSFIHDFHEVMQ
LETDVLRYMFQQVAKNCEKELQLLQIEVPVITEIPKITLLEAQEILKSKYCKESPVGDLDTEGEKLLGKYVKETYKSEFV
FITHYPKEARPMYTMPNNENSSITDSFDLLYKGLEITSGAQRIHNYEMLLDSFKGKGLHPDKFQSYLNTFRYGCPPHGGF
GIGLERIVYKLLELSNVREASAFPRDCMRLIP
>Mature_432_residues
MESIMKRSLTKECTKQSGKVVLLQGWVKKIRHLGNVSFLLLRDRTGVIQCVLENEFAGYKVDVESVVHVIGEIVETTKTE
LGVELLAHEVKVINGAEQLPFEINKKKLQVGLDQLLNERVLSLRHERTAAIFKVKSTFVHSFSEFLTENDFTRIFTPKIV
SQGAEGGANVFKLPYFQKEAYLAQSPQFYKQMMVAGGLERVFEIAPVYRAEHHNSSRHLNEYISLDVELSFIHDFHEVMQ
LETDVLRYMFQQVAKNCEKELQLLQIEVPVITEIPKITLLEAQEILKSKYCKESPVGDLDTEGEKLLGKYVKETYKSEFV
FITHYPKEARPMYTMPNNENSSITDSFDLLYKGLEITSGAQRIHNYEMLLDSFKGKGLHPDKFQSYLNTFRYGCPPHGGF
GIGLERIVYKLLELSNVREASAFPRDCMRLIP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI45439306, Length=457, Percent_Identity=36.5426695842451, Blast_Score=289, Evalue=3e-78,
Organism=Homo sapiens, GI4758762, Length=436, Percent_Identity=30.5045871559633, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI226491502, Length=438, Percent_Identity=28.5388127853881, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI40789249, Length=283, Percent_Identity=29.3286219081272, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1787161, Length=448, Percent_Identity=26.7857142857143, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789256, Length=455, Percent_Identity=24.8351648351648, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790571, Length=450, Percent_Identity=24.8888888888889, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788173, Length=252, Percent_Identity=26.5873015873016, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17551876, Length=451, Percent_Identity=37.2505543237251, Blast_Score=290, Evalue=7e-79,
Organism=Caenorhabditis elegans, GI71984122, Length=444, Percent_Identity=27.4774774774775, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17556372, Length=405, Percent_Identity=27.4074074074074, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32566633, Length=252, Percent_Identity=30.5555555555556, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323011, Length=457, Percent_Identity=36.3238512035011, Blast_Score=284, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6321807, Length=443, Percent_Identity=30.2483069977427, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6319872, Length=479, Percent_Identity=26.7223382045929, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6325153, Length=240, Percent_Identity=27.0833333333333, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17136276, Length=454, Percent_Identity=37.2246696035242, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI19921528, Length=446, Percent_Identity=28.0269058295964, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI19922416, Length=446, Percent_Identity=22.8699551569507, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24584738, Length=292, Percent_Identity=31.8493150684932, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020780
- InterPro:   IPR004523
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 49545; Mature: 49545

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESIMKRSLTKECTKQSGKVVLLQGWVKKIRHLGNVSFLLLRDRTGVIQCVLENEFAGYK
CCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCE
VDVESVVHVIGEIVETTKTELGVELLAHEVKVINGAEQLPFEINKKKLQVGLDQLLNERV
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHH
LSLRHERTAAIFKVKSTFVHSFSEFLTENDFTRIFTPKIVSQGAEGGANVFKLPYFQKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHCCCCCCCCEEECCCHHHHH
YLAQSPQFYKQMMVAGGLERVFEIAPVYRAEHHNSSRHLNEYISLDVELSFIHDFHEVMQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEHHHHHHHHHHHH
LETDVLRYMFQQVAKNCEKELQLLQIEVPVITEIPKITLLEAQEILKSKYCKESPVGDLD
HHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC
TEGEKLLGKYVKETYKSEFVFITHYPKEARPMYTMPNNENSSITDSFDLLYKGLEITSGA
CCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCCCCCCHHHHHHHHHCCHHCHHH
QRIHNYEMLLDSFKGKGLHPDKFQSYLNTFRYGCPPHGGFGIGLERIVYKLLELSNVREA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHH
SAFPRDCMRLIP
HCCCHHHHHHCC
>Mature Secondary Structure
MESIMKRSLTKECTKQSGKVVLLQGWVKKIRHLGNVSFLLLRDRTGVIQCVLENEFAGYK
CCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCE
VDVESVVHVIGEIVETTKTELGVELLAHEVKVINGAEQLPFEINKKKLQVGLDQLLNERV
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHH
LSLRHERTAAIFKVKSTFVHSFSEFLTENDFTRIFTPKIVSQGAEGGANVFKLPYFQKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHCCCCCCCCEEECCCHHHHH
YLAQSPQFYKQMMVAGGLERVFEIAPVYRAEHHNSSRHLNEYISLDVELSFIHDFHEVMQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEHHHHHHHHHHHH
LETDVLRYMFQQVAKNCEKELQLLQIEVPVITEIPKITLLEAQEILKSKYCKESPVGDLD
HHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC
TEGEKLLGKYVKETYKSEFVFITHYPKEARPMYTMPNNENSSITDSFDLLYKGLEITSGA
CCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCCCCCCHHHHHHHHHCCHHCHHH
QRIHNYEMLLDSFKGKGLHPDKFQSYLNTFRYGCPPHGGFGIGLERIVYKLLELSNVREA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHH
SAFPRDCMRLIP
HCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]