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The map label for this gene is rpiR [C]

Identifier: 52143190

GI number: 52143190

Start: 2166378

End: 2166908

Strand: Direct

Name: rpiR [C]

Synonym: BCZK2047

Alternate gene names: 52143190

Gene position: 2166378-2166908 (Clockwise)

Preceding gene: 52143191

Following gene: 52143189

Centisome position: 40.87

GC content: 37.85

Gene sequence:

>531_bases
ATGAATAACTGTGTCACATTGCATTTGTTAAATGATACAGCGCTAGAGCAAGCTGTAAAAGCTTTACAAGAAGCGAATCG
AATTGAGTTTTATGGAAATGGTGGCTCTGGTATTATTGCGACGGATGCGTATCATAAGTTTATGAGAACGGGTATTTCAT
GTATCGCTCATACTGATTCGCATTTTCAAATTATGGGAGCAGCTTTACTCTCGAAAAATTCAGTTGTTATCGGCATTTCT
CATTCTGGTAGCAATAAAGGGTTACTTGAAGCGTTAGAAGTAGCGAAAGCAAGAGGAGCTAAAATTATTGCGATTACGAG
CTATCAGAAATCGGCATTAAGTCAACTTACTGATATAACGCTCTATACTTCAACACGTGAGACAGAATTCCGCACAGAAG
CAAGTTCATCACGATTAGCACAGTTAAGTTTAATTGATACTTTGTATGTAGGGTTGTCGTTGCAACGACAGGAGGAAACG
TTAAAACATTTACAAAGTATACGTGAAACGATTTCGATGAGGCGAAAATAA

Upstream 100 bases:

>100_bases
CTGTGAAAACACATGTTTCAAATATTTTAGCTAAATTGGAAGTAGATGATCGTACGCAAGCTGCACTGTACGCAGTGAAA
CACGGCGAGAAATAATAAGT

Downstream 100 bases:

>100_bases
GAAAAGCTCTTCAAATGAAGGGCTTTTTTTATTTTCTTGTAGAAATATGTGGCTTACTTATAGCCAGTGATAGACTCTCA
TTTTTTAAAATATAAAATAA

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MNNCVTLHLLNDTALEQAVKALQEANRIEFYGNGGSGIIATDAYHKFMRTGISCIAHTDSHFQIMGAALLSKNSVVIGIS
HSGSNKGLLEALEVAKARGAKIIAITSYQKSALSQLTDITLYTSTRETEFRTEASSSRLAQLSLIDTLYVGLSLQRQEET
LKHLQSIRETISMRRK

Sequences:

>Translated_176_residues
MNNCVTLHLLNDTALEQAVKALQEANRIEFYGNGGSGIIATDAYHKFMRTGISCIAHTDSHFQIMGAALLSKNSVVIGIS
HSGSNKGLLEALEVAKARGAKIIAITSYQKSALSQLTDITLYTSTRETEFRTEASSSRLAQLSLIDTLYVGLSLQRQEET
LKHLQSIRETISMRRK
>Mature_176_residues
MNNCVTLHLLNDTALEQAVKALQEANRIEFYGNGGSGIIATDAYHKFMRTGISCIAHTDSHFQIMGAALLSKNSVVIGIS
HSGSNKGLLEALEVAKARGAKIIAITSYQKSALSQLTDITLYTSTRETEFRTEASSSRLAQLSLIDTLYVGLSLQRQEET
LKHLQSIRETISMRRK

Specific function: Regulatory Protein Involved In Rpib Gene Repression. Also Involved In Als Operon Repression. [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082369, Length=145, Percent_Identity=35.1724137931034, Blast_Score=106, Evalue=8e-25,
Organism=Escherichia coli, GI1788767, Length=160, Percent_Identity=37.5, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788159, Length=168, Percent_Identity=32.1428571428571, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI87082130, Length=166, Percent_Identity=29.5180722891566, Blast_Score=63, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 19315; Mature: 19315

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNCVTLHLLNDTALEQAVKALQEANRIEFYGNGGSGIIATDAYHKFMRTGISCIAHTDS
CCCEEEEEEECHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHHHHHHHHHEEECCC
HFQIMGAALLSKNSVVIGISHSGSNKGLLEALEVAKARGAKIIAITSYQKSALSQLTDIT
HHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHEE
LYTSTRETEFRTEASSSRLAQLSLIDTLYVGLSLQRQEETLKHLQSIRETISMRRK
EEECCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNCVTLHLLNDTALEQAVKALQEANRIEFYGNGGSGIIATDAYHKFMRTGISCIAHTDS
CCCEEEEEEECHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHHHHHHHHHEEECCC
HFQIMGAALLSKNSVVIGISHSGSNKGLLEALEVAKARGAKIIAITSYQKSALSQLTDIT
HHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHEE
LYTSTRETEFRTEASSSRLAQLSLIDTLYVGLSLQRQEETLKHLQSIRETISMRRK
EEECCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]