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The map label for this gene is opuBB [H]

Identifier: 52143178

GI number: 52143178

Start: 2181251

End: 2182762

Strand: Direct

Name: opuBB [H]

Synonym: BCZK2060

Alternate gene names: 52143178

Gene position: 2181251-2182762 (Clockwise)

Preceding gene: 52143177

Following gene: 52143176

Centisome position: 41.15

GC content: 35.58

Gene sequence:

>1512_bases
GTGACTGATTTTATACAAACGTTTCAAGAACGAAAAATAGAATTACTAACTGCATTAAGTGAGCATTTACAAATATCGCT
TATTTCATTATTTTTTGCAGTAATTATTGCGGTACCGCTTGGCATTTTATTAACGAGAAAAGAAAGAATGGCTGAGTTGA
TTATAGGAACTTCTGCAGTTATGCAGACCGTCCCATCACTTGCATTACTCGGACTATTAATTCCGTTGGTAGGAATCGGA
AAAATCCCGGCCGTTATTGCATTAGTTGTATATGCACTATTACCTATTTTACGCAATACATATACAGGAATACGGGAGTT
AGATGAATCTTTAATCGAAGCAGCGAAAGCTATGGGGATGAATAGTTGGAGAAGACTGTGGAAGGTAGAGCTTCCTCTTG
CCTTACCAATTATTATGGCCGGTATTCGTACGGCAATGGTATTAATTGTTGGAACAGCTACATTAGCAGCTCTTATAGGT
GCTGGTGGACTCGGTAAACTCATATTACTTGGTATTGATCGGAATGATCATGCACTTATTATTTTAGGGGCCGTACCAGC
CGCGTTACTCGCTTTATTCTTTGATGTAGTACTTCGAGTGCTTGAGAAGCCAAAACGCTCGTCTAAGCGTGTTATATTGA
CGATATGTATCGTTTGTATAATGGTTGCTTCTCCATTTCTTTGGAATACAGAAAAGAAAGATATTGTTATTGCGGGCAAA
CTTGGATCAGAACCTGAAATTTTAGTTCAAATGTATAAGCAGCTTATTGAACAAGATACGGATTTACACGTACAATTAAA
ACCAGGTCTTGGCAAAACAGCATTTGTATTTGAAGCGTTGAAATCAGGAGAAGTAGATATATATCCTGAGTTTTCGGGAA
CAGCTTTATCTACTTTCGTGAAAGAAGAGCCAAAAAGTACAAATCGGGATGAAGTATATGAGCAGGCTCGCATTGGAATG
GAAAAGAAATATAATATGGTTATGTTGAAGCCGATGGAGTATAACAATACATATGCACTGGCTATGCCGAAAAAAATAGC
AGATCAAAATAATATAAATACAATCTCTGATTTAGGAAATATTGCACAGGATACGAAAGTAGGATTCACATTAGAATTTG
CTGATCGTGAAGACGGTTATAAAGGAATGCAAAAGTTATATAACTATAAGTTTTCAAATGTGAAAACGATGGAACCGAAA
TTACGTTACAGTGCAATTCAATCAGGGGATGTTAACGTAATCGATGCATATTCAACAGATAGTGAATTGGAGCAATACGG
ACTTAAAGTGCTAAAAGATGATAAAGGGTTATTCCCACCATACCAAGGTGCACCATTATTAAGAAAAGAGACGTTACAAA
AATATCCTGAACTTGAAAAAGTATTAAATAAATTATCTGGAAAGATTACAGATGAAGAAATGCGAAAAATGAATTATGAA
GTAAATGTGAATGGTAAAAATAGTGAAGAAGTAGCGAAACAATTTTTACAAAAAGAGAATTTACTTCGTTAA

Upstream 100 bases:

>100_bases
AGTCGTTCCAGTTGAAGAAAATGGTCGATATGTTGGAGCTTTAACGAGTCGTCATATTGTCAATTATATTGTTGAACAAA
TGAAGGAAAGAGGCTAAACA

Downstream 100 bases:

>100_bases
ATTTACAAGAAATATACAAATTTATATGTATGAAATGACCGTTCATTACAAAATGAACGGTTTTTTTGTGCATACTTATA
CATTTTTTCAAAAAAGTATT

Product: glycine betaine/choline ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MTDFIQTFQERKIELLTALSEHLQISLISLFFAVIIAVPLGILLTRKERMAELIIGTSAVMQTVPSLALLGLLIPLVGIG
KIPAVIALVVYALLPILRNTYTGIRELDESLIEAAKAMGMNSWRRLWKVELPLALPIIMAGIRTAMVLIVGTATLAALIG
AGGLGKLILLGIDRNDHALIILGAVPAALLALFFDVVLRVLEKPKRSSKRVILTICIVCIMVASPFLWNTEKKDIVIAGK
LGSEPEILVQMYKQLIEQDTDLHVQLKPGLGKTAFVFEALKSGEVDIYPEFSGTALSTFVKEEPKSTNRDEVYEQARIGM
EKKYNMVMLKPMEYNNTYALAMPKKIADQNNINTISDLGNIAQDTKVGFTLEFADREDGYKGMQKLYNYKFSNVKTMEPK
LRYSAIQSGDVNVIDAYSTDSELEQYGLKVLKDDKGLFPPYQGAPLLRKETLQKYPELEKVLNKLSGKITDEEMRKMNYE
VNVNGKNSEEVAKQFLQKENLLR

Sequences:

>Translated_503_residues
MTDFIQTFQERKIELLTALSEHLQISLISLFFAVIIAVPLGILLTRKERMAELIIGTSAVMQTVPSLALLGLLIPLVGIG
KIPAVIALVVYALLPILRNTYTGIRELDESLIEAAKAMGMNSWRRLWKVELPLALPIIMAGIRTAMVLIVGTATLAALIG
AGGLGKLILLGIDRNDHALIILGAVPAALLALFFDVVLRVLEKPKRSSKRVILTICIVCIMVASPFLWNTEKKDIVIAGK
LGSEPEILVQMYKQLIEQDTDLHVQLKPGLGKTAFVFEALKSGEVDIYPEFSGTALSTFVKEEPKSTNRDEVYEQARIGM
EKKYNMVMLKPMEYNNTYALAMPKKIADQNNINTISDLGNIAQDTKVGFTLEFADREDGYKGMQKLYNYKFSNVKTMEPK
LRYSAIQSGDVNVIDAYSTDSELEQYGLKVLKDDKGLFPPYQGAPLLRKETLQKYPELEKVLNKLSGKITDEEMRKMNYE
VNVNGKNSEEVAKQFLQKENLLR
>Mature_502_residues
TDFIQTFQERKIELLTALSEHLQISLISLFFAVIIAVPLGILLTRKERMAELIIGTSAVMQTVPSLALLGLLIPLVGIGK
IPAVIALVVYALLPILRNTYTGIRELDESLIEAAKAMGMNSWRRLWKVELPLALPIIMAGIRTAMVLIVGTATLAALIGA
GGLGKLILLGIDRNDHALIILGAVPAALLALFFDVVLRVLEKPKRSSKRVILTICIVCIMVASPFLWNTEKKDIVIAGKL
GSEPEILVQMYKQLIEQDTDLHVQLKPGLGKTAFVFEALKSGEVDIYPEFSGTALSTFVKEEPKSTNRDEVYEQARIGME
KKYNMVMLKPMEYNNTYALAMPKKIADQNNINTISDLGNIAQDTKVGFTLEFADREDGYKGMQKLYNYKFSNVKTMEPKL
RYSAIQSGDVNVIDAYSTDSELEQYGLKVLKDDKGLFPPYQGAPLLRKETLQKYPELEKVLNKLSGKITDEEMRKMNYEV
NVNGKNSEEVAKQFLQKENLLR

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=185, Percent_Identity=41.6216216216216, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788451, Length=200, Percent_Identity=40, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1789033, Length=176, Percent_Identity=38.0681818181818, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788452, Length=310, Percent_Identity=26.4516129032258, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87081802, Length=157, Percent_Identity=33.7579617834395, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 56104; Mature: 55973

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFIQTFQERKIELLTALSEHLQISLISLFFAVIIAVPLGILLTRKERMAELIIGTSAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQTVPSLALLGLLIPLVGIGKIPAVIALVVYALLPILRNTYTGIRELDESLIEAAKAMGM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NSWRRLWKVELPLALPIIMAGIRTAMVLIVGTATLAALIGAGGLGKLILLGIDRNDHALI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEE
ILGAVPAALLALFFDVVLRVLEKPKRSSKRVILTICIVCIMVASPFLWNTEKKDIVIAGK
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
LGSEPEILVQMYKQLIEQDTDLHVQLKPGLGKTAFVFEALKSGEVDIYPEFSGTALSTFV
CCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHH
KEEPKSTNRDEVYEQARIGMEKKYNMVMLKPMEYNNTYALAMPKKIADQNNINTISDLGN
HHCCCCCCHHHHHHHHHCCHHCCCCEEEEEEECCCCEEEEECCHHHCCCCCCCHHHHHHH
IAQDTKVGFTLEFADREDGYKGMQKLYNYKFSNVKTMEPKLRYSAIQSGDVNVIDAYSTD
HHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEECCCHHHHHHHCCCCCEEEECCCCH
SELEQYGLKVLKDDKGLFPPYQGAPLLRKETLQKYPELEKVLNKLSGKITDEEMRKMNYE
HHHHHHCHHHEECCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHCCCE
VNVNGKNSEEVAKQFLQKENLLR
EEECCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDFIQTFQERKIELLTALSEHLQISLISLFFAVIIAVPLGILLTRKERMAELIIGTSAV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQTVPSLALLGLLIPLVGIGKIPAVIALVVYALLPILRNTYTGIRELDESLIEAAKAMGM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NSWRRLWKVELPLALPIIMAGIRTAMVLIVGTATLAALIGAGGLGKLILLGIDRNDHALI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEE
ILGAVPAALLALFFDVVLRVLEKPKRSSKRVILTICIVCIMVASPFLWNTEKKDIVIAGK
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
LGSEPEILVQMYKQLIEQDTDLHVQLKPGLGKTAFVFEALKSGEVDIYPEFSGTALSTFV
CCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHH
KEEPKSTNRDEVYEQARIGMEKKYNMVMLKPMEYNNTYALAMPKKIADQNNINTISDLGN
HHCCCCCCHHHHHHHHHCCHHCCCCEEEEEEECCCCEEEEECCHHHCCCCCCCHHHHHHH
IAQDTKVGFTLEFADREDGYKGMQKLYNYKFSNVKTMEPKLRYSAIQSGDVNVIDAYSTD
HHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEECCCHHHHHHHCCCCCEEEECCCCH
SELEQYGLKVLKDDKGLFPPYQGAPLLRKETLQKYPELEKVLNKLSGKITDEEMRKMNYE
HHHHHHCHHHEECCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHCCCE
VNVNGKNSEEVAKQFLQKENLLR
EEECCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]