| Definition | Bacillus cereus E33L, complete genome. |
|---|---|
| Accession | NC_006274 |
| Length | 5,300,915 |
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The map label for this gene is pbp1A [H]
Identifier: 52143132
GI number: 52143132
Start: 2225837
End: 2228344
Strand: Direct
Name: pbp1A [H]
Synonym: BCZK2108
Alternate gene names: 52143132
Gene position: 2225837-2228344 (Clockwise)
Preceding gene: 52143131
Following gene: 52143129
Centisome position: 41.99
GC content: 36.76
Gene sequence:
>2508_bases ATGTCAGAAAATTATCGTTCTCGAGAGGAGCGACGACAAGTTAAAAAGAAAAAACAACCAGCTTCTAAAACACAAAAACC AAAAGGTAAAACATCATTCTTTCGCAAGTTTTTAATTACTTGTTTATTACTTGGTATTGTTGGTTTAGTGGGGGGAGTTG CTACCTTTTTCGTAATGATTAAGGATGCACCAAAACTTGAGAAAGCAAAACTTGTTAATCCGTTATCCTCAAAAATTTAT GATAAAAATGGCGATTTGGTATATGAATACGGGAAAGAAAAACGGACGAATGTTACGTATGATCAAATTCCTAAATTAGT AGAAAATGCATTTTTAGCAACAGAAGATGCACGTTTTTACGAGCATAGTGGAGTAGACTTTAAAGGTACTGCTCGTGCTG TTTTGGTGAGTCTTAAAGGTGATTACGGTTCACAAGGTGGAAGTACGATAACACAGCAGGTTATTAAAAATTACTTCTTA TCGATGGAAAAAACATCAAAACGTAAGATTCAAGAAATATATTTAGCGTATAAGCTAGAACAACAGTATTCAAAACATGA AATTTTAGAAATGTATTTAAATAAAATTAATTTAGGTAATCGTTCATATGGTATCGCAACAGCAGCACAAAACTACTACG GTAAAGAATTAAAAGAGTTAACTTTACCAGAAGTTGCGATGCTGGCAGGTTTACCAAAAGCACCGAATAACTATGATCCA ACGAAGACAGAAAATGTTCAAAGAGCAACAGAAAGAAGAAATGTTGTCCTAAAATTAATGAATCGACATGGTTATATTAC GAAGGCAGAAATGGAAGAAGCTTCGAAAGTTGAAGTAACAGATGGACTTAAGACTGCAACTGTACAAGCAATGCCATATC CTGCATTTATGGATGCGGTTGTGAAAGAAGTTGAAAAAGAATTGCCAGATGCTAATATTGGTTCTGACGGTTTAGAAATT TATACAACATTAGACACGAGAGCACAGGATTTTGCTGATAAGATTTTAAATGAAAATATTATTAATTATCCAAATGATAA ATTCCAAGGTGCTTTCACATTTATGGATACGAAAACAGGAGAAGTTCGTGCTATAGGTAGTGGACGCGGTGAAAATAAAG CAGTATTTAAAGGGCATAATATGGCCATTGAATTAGATCGTGCAGCTGGTTCGACGATGAAGCCAATCTTTGATTACGGT CCTGCAATTGAATACTTAAAATGGGCTACGTATCATCAAATTGATGATTCTCCATTTAAATATTCAACTGGACAAGAAGT TCGAAATGCCGACAGAAGTCATTTAGGATCTATTACGATGCGTGAAGCATTAAAAATGTCGCGTAACGTCCCGGCAGTTA AAACTGCAAAAGAAGTAGGACTTAATAAAGCGAAGGAATTCTCTGAGAAATTAGGTATTACACTTAAGTCAGTACCAGAA TCTACAGCGATTGGTACAAACGAAGTATCACCAACTGAAATAGCGGGTGCTTATGCGACATTTGGTAATGGTGGAAAGTA TGCAAAACCGCATTTTGTTAAGAAAGTAGTTTATCCAGACGGTAAGTCACAAAGTTTCGGGCAAAAACCAAAACAAGTTA TAGCTGACTCTACAGCATATATGATTACTGATATGCTTCGTTCAGTAGTGACATCAGGTACTGGTACAGCTGCAAATATT AGTTCTTTAGATATAGCTGGTAAAACAGGTACAACAAACTATGATTCAAAACAATTAGCGAAATTTAATATTCCAGAAAG TGCAACTCGTGATAGTTGGTTTGCAGGTTACACGCCGCAGTATACGATGGCAGTATGGACTGGATATATGAAAGATGGTA AAGACGAGTATATTAGTAGTAAAAATACGAAAATTGCACAATTGATCTTTAAACAAATGATGAGTAAGTTTGCTACTGAC CAATCACGATTTAAAATGCCAAGTAGTGTAATTCAAGAAGGAAGTGAGCTACGTATAAAAGGTGAAAAACGTGATTCTTC TCCAAATACGAGCGTACCTGACACAACAGAACAACCAAAACAAAATCAGCAGCAAAAAACGGAAGAAGAGAAAAAGCAAG AAGAATTAAAGAAACAGGAAGAATTGAAAAAACAAGAAGAACAAAAGCAACAAGAGGAACTTAAGAAGCAAGAAGAACAA AAGAAACTAGAAGAGCAAAAGAAACAAGAAGAAGAAAAGAAACAAAATGAACAAAATAATGGAGGAGGCCAAGGGAATAC GACACCTCCAGCAAATAACGGGGGAGGTCAAGGAAATACGACACCTCCAGCAAATAACGGAGGAGGCCAAGGAAATACGA CACCTCCAGCAAATAACGGAGGAGGTCAAGGAAATACGACACCTCCAGCAAATAACGGAGGAGGTCAAGGAAATACAACC CCTCCAGCAAATAATGGAGGAGGTCAAGGAAATACAACTCCACCAGCGACCACACAACCAGAGACTGGCGGTAATGCAGG AGAGACCCCTGCTAATAATGGACAATAA
Upstream 100 bases:
>100_bases CTCCAGGTCAATATACTTTCTTAATTTAATTCATTTTAGAAAGTGACCTCAATATTTTTAAGTAAATCAACGGGAGAATT GAAAGGCAGGAGAAAGTAAC
Downstream 100 bases:
>100_bases GAAAATTTTATGAAAATTATTAAAAAGCACTTAAGATTTGTAGACATTACAATCTTAAGTGCTTTTTTCTTTTAAATGCA GTAGCTATGAGACAATGTAT
Product: penicillin-binding protein 1A
Products: NA
Alternate protein names: PBP1; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 835; Mature: 834
Protein sequence:
>835_residues MSENYRSREERRQVKKKKQPASKTQKPKGKTSFFRKFLITCLLLGIVGLVGGVATFFVMIKDAPKLEKAKLVNPLSSKIY DKNGDLVYEYGKEKRTNVTYDQIPKLVENAFLATEDARFYEHSGVDFKGTARAVLVSLKGDYGSQGGSTITQQVIKNYFL SMEKTSKRKIQEIYLAYKLEQQYSKHEILEMYLNKINLGNRSYGIATAAQNYYGKELKELTLPEVAMLAGLPKAPNNYDP TKTENVQRATERRNVVLKLMNRHGYITKAEMEEASKVEVTDGLKTATVQAMPYPAFMDAVVKEVEKELPDANIGSDGLEI YTTLDTRAQDFADKILNENIINYPNDKFQGAFTFMDTKTGEVRAIGSGRGENKAVFKGHNMAIELDRAAGSTMKPIFDYG PAIEYLKWATYHQIDDSPFKYSTGQEVRNADRSHLGSITMREALKMSRNVPAVKTAKEVGLNKAKEFSEKLGITLKSVPE STAIGTNEVSPTEIAGAYATFGNGGKYAKPHFVKKVVYPDGKSQSFGQKPKQVIADSTAYMITDMLRSVVTSGTGTAANI SSLDIAGKTGTTNYDSKQLAKFNIPESATRDSWFAGYTPQYTMAVWTGYMKDGKDEYISSKNTKIAQLIFKQMMSKFATD QSRFKMPSSVIQEGSELRIKGEKRDSSPNTSVPDTTEQPKQNQQQKTEEEKKQEELKKQEELKKQEEQKQQEELKKQEEQ KKLEEQKKQEEEKKQNEQNNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTT PPANNGGGQGNTTPPATTQPETGGNAGETPANNGQ
Sequences:
>Translated_835_residues MSENYRSREERRQVKKKKQPASKTQKPKGKTSFFRKFLITCLLLGIVGLVGGVATFFVMIKDAPKLEKAKLVNPLSSKIY DKNGDLVYEYGKEKRTNVTYDQIPKLVENAFLATEDARFYEHSGVDFKGTARAVLVSLKGDYGSQGGSTITQQVIKNYFL SMEKTSKRKIQEIYLAYKLEQQYSKHEILEMYLNKINLGNRSYGIATAAQNYYGKELKELTLPEVAMLAGLPKAPNNYDP TKTENVQRATERRNVVLKLMNRHGYITKAEMEEASKVEVTDGLKTATVQAMPYPAFMDAVVKEVEKELPDANIGSDGLEI YTTLDTRAQDFADKILNENIINYPNDKFQGAFTFMDTKTGEVRAIGSGRGENKAVFKGHNMAIELDRAAGSTMKPIFDYG PAIEYLKWATYHQIDDSPFKYSTGQEVRNADRSHLGSITMREALKMSRNVPAVKTAKEVGLNKAKEFSEKLGITLKSVPE STAIGTNEVSPTEIAGAYATFGNGGKYAKPHFVKKVVYPDGKSQSFGQKPKQVIADSTAYMITDMLRSVVTSGTGTAANI SSLDIAGKTGTTNYDSKQLAKFNIPESATRDSWFAGYTPQYTMAVWTGYMKDGKDEYISSKNTKIAQLIFKQMMSKFATD QSRFKMPSSVIQEGSELRIKGEKRDSSPNTSVPDTTEQPKQNQQQKTEEEKKQEELKKQEELKKQEEQKQQEELKKQEEQ KKLEEQKKQEEEKKQNEQNNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTT PPANNGGGQGNTTPPATTQPETGGNAGETPANNGQ >Mature_834_residues SENYRSREERRQVKKKKQPASKTQKPKGKTSFFRKFLITCLLLGIVGLVGGVATFFVMIKDAPKLEKAKLVNPLSSKIYD KNGDLVYEYGKEKRTNVTYDQIPKLVENAFLATEDARFYEHSGVDFKGTARAVLVSLKGDYGSQGGSTITQQVIKNYFLS MEKTSKRKIQEIYLAYKLEQQYSKHEILEMYLNKINLGNRSYGIATAAQNYYGKELKELTLPEVAMLAGLPKAPNNYDPT KTENVQRATERRNVVLKLMNRHGYITKAEMEEASKVEVTDGLKTATVQAMPYPAFMDAVVKEVEKELPDANIGSDGLEIY TTLDTRAQDFADKILNENIINYPNDKFQGAFTFMDTKTGEVRAIGSGRGENKAVFKGHNMAIELDRAAGSTMKPIFDYGP AIEYLKWATYHQIDDSPFKYSTGQEVRNADRSHLGSITMREALKMSRNVPAVKTAKEVGLNKAKEFSEKLGITLKSVPES TAIGTNEVSPTEIAGAYATFGNGGKYAKPHFVKKVVYPDGKSQSFGQKPKQVIADSTAYMITDMLRSVVTSGTGTAANIS SLDIAGKTGTTNYDSKQLAKFNIPESATRDSWFAGYTPQYTMAVWTGYMKDGKDEYISSKNTKIAQLIFKQMMSKFATDQ SRFKMPSSVIQEGSELRIKGEKRDSSPNTSVPDTTEQPKQNQQQKTEEEKKQEELKKQEELKKQEEQKQQEELKKQEEQK KLEEQKKQEEEKKQNEQNNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTP PANNGGGQGNTTPPATTQPETGGNAGETPANNGQ
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG0744
COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)
Gene ontology:
Cell location: Cell membrane; Single-pass type II membrane protein. Note=Probably found all over the whole cell at low concentrations. Also localizes to the division site in vegetative cells [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 fibronectin type-III domain [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=314, Percent_Identity=41.7197452229299, Blast_Score=239, Evalue=8e-64, Organism=Escherichia coli, GI1786343, Length=538, Percent_Identity=34.2007434944238, Blast_Score=231, Evalue=2e-61, Organism=Escherichia coli, GI1788867, Length=580, Percent_Identity=27.0689655172414, Blast_Score=130, Evalue=4e-31, Organism=Escherichia coli, GI1789601, Length=233, Percent_Identity=31.3304721030043, Blast_Score=91, Evalue=4e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR008957 - InterPro: IPR003961 - InterPro: IPR001264 - InterPro: IPR013783 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00041 fn3; PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 91953; Mature: 91822
Theoretical pI: Translated: 9.60; Mature: 9.60
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSENYRSREERRQVKKKKQPASKTQKPKGKTSFFRKFLITCLLLGIVGLVGGVATFFVMI CCCCCCCHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KDAPKLEKAKLVNPLSSKIYDKNGDLVYEYGKEKRTNVTYDQIPKLVENAFLATEDARFY CCCCCHHHHHHHCHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHH EHSGVDFKGTARAVLVSLKGDYGSQGGSTITQQVIKNYFLSMEKTSKRKIQEIYLAYKLE HCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH QQYSKHEILEMYLNKINLGNRSYGIATAAQNYYGKELKELTLPEVAMLAGLPKAPNNYDP HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCC TKTENVQRATERRNVVLKLMNRHGYITKAEMEEASKVEVTDGLKTATVQAMPYPAFMDAV CCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCCCEECCCCCCHHEEECCCCHHHHHHH VKEVEKELPDANIGSDGLEIYTTLDTRAQDFADKILNENIINYPNDKFQGAFTFMDTKTG HHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC EVRAIGSGRGENKAVFKGHNMAIELDRAAGSTMKPIFDYGPAIEYLKWATYHQIDDSPFK CEEEECCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCC YSTGQEVRNADRSHLGSITMREALKMSRNVPAVKTAKEVGLNKAKEFSEKLGITLKSVPE CCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCEEECCCC STAIGTNEVSPTEIAGAYATFGNGGKYAKPHFVKKVVYPDGKSQSFGQKPKQVIADSTAY CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCCCCCCCCCHHHHHHCCHHH MITDMLRSVVTSGTGTAANISSLDIAGKTGTTNYDSKQLAKFNIPESATRDSWFAGYTPQ HHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCC YTMAVWTGYMKDGKDEYISSKNTKIAQLIFKQMMSKFATDQSRFKMPSSVIQEGSELRIK HHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHCCCCCEEEE GEKRDSSPNTSVPDTTEQPKQNQQQKTEEEKKQEELKKQEELKKQEEQKQQEELKKQEEQ CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KKLEEQKKQEEEKKQNEQNNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPANNG HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPATTQPETGGNAGETPANNGQ CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure SENYRSREERRQVKKKKQPASKTQKPKGKTSFFRKFLITCLLLGIVGLVGGVATFFVMI CCCCCCHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KDAPKLEKAKLVNPLSSKIYDKNGDLVYEYGKEKRTNVTYDQIPKLVENAFLATEDARFY CCCCCHHHHHHHCHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHH EHSGVDFKGTARAVLVSLKGDYGSQGGSTITQQVIKNYFLSMEKTSKRKIQEIYLAYKLE HCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH QQYSKHEILEMYLNKINLGNRSYGIATAAQNYYGKELKELTLPEVAMLAGLPKAPNNYDP HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCC TKTENVQRATERRNVVLKLMNRHGYITKAEMEEASKVEVTDGLKTATVQAMPYPAFMDAV CCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCCCEECCCCCCHHEEECCCCHHHHHHH VKEVEKELPDANIGSDGLEIYTTLDTRAQDFADKILNENIINYPNDKFQGAFTFMDTKTG HHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC EVRAIGSGRGENKAVFKGHNMAIELDRAAGSTMKPIFDYGPAIEYLKWATYHQIDDSPFK CEEEECCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCC YSTGQEVRNADRSHLGSITMREALKMSRNVPAVKTAKEVGLNKAKEFSEKLGITLKSVPE CCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCEEECCCC STAIGTNEVSPTEIAGAYATFGNGGKYAKPHFVKKVVYPDGKSQSFGQKPKQVIADSTAY CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCCCCCCCCCHHHHHHCCHHH MITDMLRSVVTSGTGTAANISSLDIAGKTGTTNYDSKQLAKFNIPESATRDSWFAGYTPQ HHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCC YTMAVWTGYMKDGKDEYISSKNTKIAQLIFKQMMSKFATDQSRFKMPSSVIQEGSELRIK HHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHCCCCCEEEE GEKRDSSPNTSVPDTTEQPKQNQQQKTEEEKKQEELKKQEELKKQEEQKQQEELKKQEEQ CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KKLEEQKKQEEEKKQNEQNNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPANNG HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPATTQPETGGNAGETPANNGQ CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7814321; 8760912; 9384377; 9721295; 10322023 [H]