Click here to switch to the map view.

The map label for this gene is yfiS [H]

Identifier: 52142922

GI number: 52142922

Start: 2452179

End: 2453405

Strand: Reverse

Name: yfiS [H]

Synonym: BCZK2318

Alternate gene names: 52142922

Gene position: 2453405-2452179 (Counterclockwise)

Preceding gene: 52142917

Following gene: 52142938

Centisome position: 46.28

GC content: 34.23

Gene sequence:

>1227_bases
GTGAAACTTATACAAGAACGTAGCCTTACCGTAAAGACAACTTTTTCTAAAGAATACAAGATTTTTATTTTTGGTTTACT
CATTTCACGAATTGGAGACTCATTGTATACTTTTGCGTTACCTTGGATTGCCTATCAATTAACCGGTTCAGCTGTAATTA
TGAGTTCTTTATTTGCTATTAACGTATTACCAATCGTTTTATTTGGCCCTTTAGTTGGTATAATAATTGATCGTTATGAT
CGAAAAAAGTTACTTTTGGTAGCGGATATTACCAATATTATTTTAGTAAGCTTTGTACCAATACTACATTCATTACACCT
ATTAGAAATCTGGCATTTATACATAATTACTTTTATGTTAGCAGTTATGTCCATGCTTTTTGATGTAACAACTGTTACAG
TCATCCCGCAAATTGCCGGAGCATCCTTAACGAAAGCCAATTCTTTCTATCAAATGGTCAATCAATTAGCCAGTTTATTT
GGTCCAATGATAGCTGGGGTTTTCATTTCTTTTATTGGCGGCTTTCAGTTGCTTTGGATTAATGTTCTTTCATTTATTGC
TACATTAGTTGCTGTGATGTTATTACCGTCTATGAAAACCACAAATAAAAAATGTGAAGATAAAAATACACTTCAAAATG
TACTATATGATTTGGTTAATGGATTTAAATGGCTCAAAAATGATCGCTTAAATTTAGTCTTATCTTTTCAAGCTATGATA
GGAAACTTTGGAGCAAGTGCGGTTTTAGGTGTATTCATGTATTATTTATTATCCACATTACAACTTACCCCAGAACAAAG
TGGGGTGAATTATTCATTAATTGGAATAGGTGGTCTTTTAGGAAGCTTGATTGCAGTTCCTTTAGAAAAGAGGTTACAGC
GCGGCATACTAATCCCTTTACTCTTATTTGTTGGGGCAATCGGCTTAACTTTTGCACTTTGGAGCACATATTGGCTCGCT
CCCGGAATTGCTTTCGGTGTTGCAATGACTTGTAATATTGCATGGAATACAATTGTAGCCACAATTCGTCAGGAAACAGT
TCCATCAAATATGCAAGGAAGAGTTTTAGGATTTTCACGTGTACTTACACGATTAGCTATGCCACTCGGGGCATTAGTAG
GAGGCATTATTTCAGCTTATAATCCTGCCTTTGTATTTGCTTTAGCTGCTTTTACTAAATTAATTGAAGTCTTTATTGCT
TTATATAGTCCGATACGAAAACTATAA

Upstream 100 bases:

>100_bases
GTAAAAGTAGGATTCATCAAAAAATTACAGAATTCTATATATAACAAATATTGGACGGATTATTTTCAAATTCCTCTATA
ATAAAGGTGGTATAAACAGT

Downstream 100 bases:

>100_bases
TAGTAGGAAAGATAATTATGATTGGTTAATTGCAATTACGGATAAGTTTATAAAGGAAAAAGGCATATTATAATGCCTTT
TTTCTTTATCATCATTTAAC

Product: macrolide-efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKLIQERSLTVKTTFSKEYKIFIFGLLISRIGDSLYTFALPWIAYQLTGSAVIMSSLFAINVLPIVLFGPLVGIIIDRYD
RKKLLLVADITNIILVSFVPILHSLHLLEIWHLYIITFMLAVMSMLFDVTTVTVIPQIAGASLTKANSFYQMVNQLASLF
GPMIAGVFISFIGGFQLLWINVLSFIATLVAVMLLPSMKTTNKKCEDKNTLQNVLYDLVNGFKWLKNDRLNLVLSFQAMI
GNFGASAVLGVFMYYLLSTLQLTPEQSGVNYSLIGIGGLLGSLIAVPLEKRLQRGILIPLLLFVGAIGLTFALWSTYWLA
PGIAFGVAMTCNIAWNTIVATIRQETVPSNMQGRVLGFSRVLTRLAMPLGALVGGIISAYNPAFVFALAAFTKLIEVFIA
LYSPIRKL

Sequences:

>Translated_408_residues
MKLIQERSLTVKTTFSKEYKIFIFGLLISRIGDSLYTFALPWIAYQLTGSAVIMSSLFAINVLPIVLFGPLVGIIIDRYD
RKKLLLVADITNIILVSFVPILHSLHLLEIWHLYIITFMLAVMSMLFDVTTVTVIPQIAGASLTKANSFYQMVNQLASLF
GPMIAGVFISFIGGFQLLWINVLSFIATLVAVMLLPSMKTTNKKCEDKNTLQNVLYDLVNGFKWLKNDRLNLVLSFQAMI
GNFGASAVLGVFMYYLLSTLQLTPEQSGVNYSLIGIGGLLGSLIAVPLEKRLQRGILIPLLLFVGAIGLTFALWSTYWLA
PGIAFGVAMTCNIAWNTIVATIRQETVPSNMQGRVLGFSRVLTRLAMPLGALVGGIISAYNPAFVFALAAFTKLIEVFIA
LYSPIRKL
>Mature_408_residues
MKLIQERSLTVKTTFSKEYKIFIFGLLISRIGDSLYTFALPWIAYQLTGSAVIMSSLFAINVLPIVLFGPLVGIIIDRYD
RKKLLLVADITNIILVSFVPILHSLHLLEIWHLYIITFMLAVMSMLFDVTTVTVIPQIAGASLTKANSFYQMVNQLASLF
GPMIAGVFISFIGGFQLLWINVLSFIATLVAVMLLPSMKTTNKKCEDKNTLQNVLYDLVNGFKWLKNDRLNLVLSFQAMI
GNFGASAVLGVFMYYLLSTLQLTPEQSGVNYSLIGIGGLLGSLIAVPLEKRLQRGILIPLLLFVGAIGLTFALWSTYWLA
PGIAFGVAMTCNIAWNTIVATIRQETVPSNMQGRVLGFSRVLTRLAMPLGALVGGIISAYNPAFVFALAAFTKLIEVFIA
LYSPIRKL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45000; Mature: 45000

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]