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The map label for this gene is nhoA [H]

Identifier: 52142784

GI number: 52142784

Start: 2588489

End: 2589256

Strand: Reverse

Name: nhoA [H]

Synonym: BCZK2456

Alternate gene names: 52142784

Gene position: 2589256-2588489 (Counterclockwise)

Preceding gene: 52142782

Following gene: 52142785

Centisome position: 48.85

GC content: 32.29

Gene sequence:

>768_bases
ATGACAAGTCTACAACATAAGCTGTTTACAAGATTGAATCTTGCAAACCGTACCGAAGTAAAGTTTGAAGAATTAAATAC
AATTCTCTTTACATTTGCACACACTATACCATTTGAGAATTTAGATGTTATAGCAAGTAACACGAATACAATTACTATGG
AAAATTTACAGAATAAAATTTTAAGTAGATCCCGCGGCGGACTTTGTTATGAATTAAATACGCTTTTTTATTACTTTTTA
AAAGATTGTGGTTATGATGTACAACTCGCATTAGGTACCGTATATAAAAATGATATAAACGTATGGGCACTTGAGAATGG
ACATATAACGATTATTCTAAATTATGATAAAGTACGATACGTAATTGATGTAGGTATTGCTTCACTAGTACCTCTAGTCC
CTGTACCTTTTACTGGTGAGTCTGTTTCTTCTAAAAATGGTACGTATCGAGTGAGACGAAAAGATACGAGTAAAGGGAAT
TACGTTCTAGAAAGAAAAGATACGAACGGTGAGTGGAAAGTATGTCACGCTTTTTATAATCGTATGATTGATGAGGTAGT
AGTGAATGATGTTCAAAAAAGAGTAGTAGAAGATGAGAAATCTATTTTCAATAAAGGACCAATTGCAGTCAAATTGACGA
ACTCTGGCCATGTCTCTTTAACAAATACTAGTTTAACTGAAATGATTCATGGGGAAAAAGCGAAACGTGAAATTACAGAA
GATCAATATAAAGAGCTTTTATATACTTTATTTGCTATTGAGTTATGA

Upstream 100 bases:

>100_bases
TACCGGTACAGTTAAATGAAATGTACATTGTTTTAGTACCCCATCGAATTTACAATCAGCATATACTATTTTAACTTATA
TATTTTAAGGGGTGCTAACT

Downstream 100 bases:

>100_bases
TAAAATAAATAGCTAGCCGGTTCTTATGAAGAATCGGTTATTTTAATTTAAAACAATTATTAAAGTTTGATTTTCGTAAT
AGATATAATACACTAGAACA

Product: N-hydroxyarylamine O-acetyltransferase

Products: CoA; an n-acetoxyarylamine [C]

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTSLQHKLFTRLNLANRTEVKFEELNTILFTFAHTIPFENLDVIASNTNTITMENLQNKILSRSRGGLCYELNTLFYYFL
KDCGYDVQLALGTVYKNDINVWALENGHITIILNYDKVRYVIDVGIASLVPLVPVPFTGESVSSKNGTYRVRRKDTSKGN
YVLERKDTNGEWKVCHAFYNRMIDEVVVNDVQKRVVEDEKSIFNKGPIAVKLTNSGHVSLTNTSLTEMIHGEKAKREITE
DQYKELLYTLFAIEL

Sequences:

>Translated_255_residues
MTSLQHKLFTRLNLANRTEVKFEELNTILFTFAHTIPFENLDVIASNTNTITMENLQNKILSRSRGGLCYELNTLFYYFL
KDCGYDVQLALGTVYKNDINVWALENGHITIILNYDKVRYVIDVGIASLVPLVPVPFTGESVSSKNGTYRVRRKDTSKGN
YVLERKDTNGEWKVCHAFYNRMIDEVVVNDVQKRVVEDEKSIFNKGPIAVKLTNSGHVSLTNTSLTEMIHGEKAKREITE
DQYKELLYTLFAIEL
>Mature_254_residues
TSLQHKLFTRLNLANRTEVKFEELNTILFTFAHTIPFENLDVIASNTNTITMENLQNKILSRSRGGLCYELNTLFYYFLK
DCGYDVQLALGTVYKNDINVWALENGHITIILNYDKVRYVIDVGIASLVPLVPVPFTGESVSSKNGTYRVRRKDTSKGNY
VLERKDTNGEWKVCHAFYNRMIDEVVVNDVQKRVVEDEKSIFNKGPIAVKLTNSGHVSLTNTSLTEMIHGEKAKREITED
QYKELLYTLFAIEL

Specific function: Unknown

COG id: COG2162

COG function: function code Q; Arylamine N-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arylamine N-acetyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787736, Length=152, Percent_Identity=25.6578947368421, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001447 [H]

Pfam domain/function: PF00797 Acetyltransf_2 [H]

EC number: 2.3.1.118 [C]

Molecular weight: Translated: 29231; Mature: 29100

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLQHKLFTRLNLANRTEVKFEELNTILFTFAHTIPFENLDVIASNTNTITMENLQNKI
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHHH
LSRSRGGLCYELNTLFYYFLKDCGYDVQLALGTVYKNDINVWALENGHITIILNYDKVRY
HHCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEEEECCEEEEEEECCCEEEEEECCCEEE
VIDVGIASLVPLVPVPFTGESVSSKNGTYRVRRKDTSKGNYVLERKDTNGEWKVCHAFYN
EEEHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHH
RMIDEVVVNDVQKRVVEDEKSIFNKGPIAVKLTNSGHVSLTNTSLTEMIHGEKAKREITE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCHHHHHHCCCHHHHHCCH
DQYKELLYTLFAIEL
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSLQHKLFTRLNLANRTEVKFEELNTILFTFAHTIPFENLDVIASNTNTITMENLQNKI
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHHH
LSRSRGGLCYELNTLFYYFLKDCGYDVQLALGTVYKNDINVWALENGHITIILNYDKVRY
HHCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEEEECCEEEEEEECCCEEEEEECCCEEE
VIDVGIASLVPLVPVPFTGESVSSKNGTYRVRRKDTSKGNYVLERKDTNGEWKVCHAFYN
EEEHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHH
RMIDEVVVNDVQKRVVEDEKSIFNKGPIAVKLTNSGHVSLTNTSLTEMIHGEKAKREITE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCHHHHHHCCCHHHHHCCH
DQYKELLYTLFAIEL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; an n-hydroxyarylamine [C]

Specific reaction: Acetyl-CoA + an n-hydroxyarylamine = CoA + an n-acetoxyarylamine [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]