Click here to switch to the map view.

The map label for this gene is yrbD [H]

Identifier: 52142687

GI number: 52142687

Start: 2677437

End: 2678927

Strand: Reverse

Name: yrbD [H]

Synonym: BCZK2555

Alternate gene names: 52142687

Gene position: 2678927-2677437 (Counterclockwise)

Preceding gene: 52142684

Following gene: 52142686

Centisome position: 50.54

GC content: 37.36

Gene sequence:

>1491_bases
ATGGAGCAATTAGTAGAGTGGTTAGTAGGGCAAGTGTGGAGTATTGGTTTAGTTGTTTTCGCGTTAGGAGCAGGTGTGTA
TTTTACAATTGCAACTCGTTTTCTTCAAATTCGTTATTTTAAAGAGATGATTAAACTATTATTTGAAGGGAAGAGCTCAG
AAACGGGAATATCATCCTTTCAAGCATTTTGTTTAGCTTTATCAGGTAGGGTTGGAATAGGTAATATTGCAGGGGTCGCG
ACAGCTATCGCTTTTGGCGGGCCTGGAGCTGTATTTTGGATGTGGGTAATGGCTCTTTTAGGAGCAGCTAGTGCCTTTGT
CGAATCAACATTATCTCAAATATATAAAAGTAAAGTTGGAAATGAATATCGCGGTGGTACACCGTATTTCATTGAAAAAG
GCTTAAACATGAAATGGTTTGCAGTCATTGTAGCGGTCGTTGTAACACTTTCATATGGTGTTTTATTACCAGGTATTCAA
TCTAGTAGTATCGCAGTTGGATTCGAAAACTCTAATGGGATTAGCAAATATATAACTGGTATCTTGTTAGTTGTATTATT
AGCAGCAATTATTTTTGGTGGCGTAAAGAGAATTGCTGGCGTTTCTCAAATGCTCGTTCCATTTATGGCAATTGGTTATG
TAATTGTTACATGTATCGTATTAATTGCGAATGTAACAGAAATCCCAAGTATGTTCGCTTTAATTTTCTCAAGTGCTTTT
GGTGTGAATGAAATGTTTGGTGGAATCGTCGGTGCAGCAATCGCGTGGGGCGTAAAGCGCGCTGTATTTTCTAATGTTGC
TGGCGTTGGAGAAGCGACGTACAGTTCGGCCGCGGCTGAAGTATCTCATCCAGCAAAACAAGGGTTAGTTCAAGCATTTT
CTGTATACATTGATACAATTGTCGTATGTACAGCGACAGCTCTTATGATCTTAATAACAGGTATGTATAATGTTATACCT
GAAGGGAAAAGCGCTATCGTAAAGAATATAGGGAATGTTGATGCGGGTCCAATTTATACACAACAAGCAGTTGAAACTGT
TATGACAGGGTTTGGTCCATTATTCATTTCAACCGCAATTTTCTTCTTCGCATTTACAACATTACTTGCATACTACTATA
TCGCTGAAACGACACTTACTTATTTAGACCGTGAGCTTAAACATAGTTGGTTAAAACCAGTTTTGAAAATTGGATTTTTA
ATTATGGTTTACATCGGTAGTGTAGAATCAGCATCGCTTTTATGGAATCTTGGAGATTTAGGAATCGGTAGTATGGCATG
GTTAAACTTAATCGCGATTCTACTATTAAGTAAAATCGCATTAAAAGTGTTAAAAGATTATGAAACGCAGAAAAAAGAAG
GGAAAGATCCCGTGTTTGATCCTAAAAATGTGGGAATTGAAGGTTTAACATTTTGGGAAGAAAGAAGAAAAGAGGTTGCA
AGAAAAAACTCTAAAGAACAAGCGGTAGTGGATGATAGTCTGAAATTTTAG

Upstream 100 bases:

>100_bases
ATGAAATAATGAGATAGACGGACAACTGGAAGTTTTAATAATAGTTGTCCGTTTTCTTATATATAAAATAGTTTTCTAAA
GAATGATAAGGGGGATTTGG

Downstream 100 bases:

>100_bases
TTTTAATAAAATGAATATTCATTCTATTTAGTGAGGTATATTGCCTTCCTTTCATCACATACTACAATAGGTACAGATAA
TTTGAATGGAGGGAATAATA

Product: sodium/proton-dependent alanine carrier protein

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MEQLVEWLVGQVWSIGLVVFALGAGVYFTIATRFLQIRYFKEMIKLLFEGKSSETGISSFQAFCLALSGRVGIGNIAGVA
TAIAFGGPGAVFWMWVMALLGAASAFVESTLSQIYKSKVGNEYRGGTPYFIEKGLNMKWFAVIVAVVVTLSYGVLLPGIQ
SSSIAVGFENSNGISKYITGILLVVLLAAIIFGGVKRIAGVSQMLVPFMAIGYVIVTCIVLIANVTEIPSMFALIFSSAF
GVNEMFGGIVGAAIAWGVKRAVFSNVAGVGEATYSSAAAEVSHPAKQGLVQAFSVYIDTIVVCTATALMILITGMYNVIP
EGKSAIVKNIGNVDAGPIYTQQAVETVMTGFGPLFISTAIFFFAFTTLLAYYYIAETTLTYLDRELKHSWLKPVLKIGFL
IMVYIGSVESASLLWNLGDLGIGSMAWLNLIAILLLSKIALKVLKDYETQKKEGKDPVFDPKNVGIEGLTFWEERRKEVA
RKNSKEQAVVDDSLKF

Sequences:

>Translated_496_residues
MEQLVEWLVGQVWSIGLVVFALGAGVYFTIATRFLQIRYFKEMIKLLFEGKSSETGISSFQAFCLALSGRVGIGNIAGVA
TAIAFGGPGAVFWMWVMALLGAASAFVESTLSQIYKSKVGNEYRGGTPYFIEKGLNMKWFAVIVAVVVTLSYGVLLPGIQ
SSSIAVGFENSNGISKYITGILLVVLLAAIIFGGVKRIAGVSQMLVPFMAIGYVIVTCIVLIANVTEIPSMFALIFSSAF
GVNEMFGGIVGAAIAWGVKRAVFSNVAGVGEATYSSAAAEVSHPAKQGLVQAFSVYIDTIVVCTATALMILITGMYNVIP
EGKSAIVKNIGNVDAGPIYTQQAVETVMTGFGPLFISTAIFFFAFTTLLAYYYIAETTLTYLDRELKHSWLKPVLKIGFL
IMVYIGSVESASLLWNLGDLGIGSMAWLNLIAILLLSKIALKVLKDYETQKKEGKDPVFDPKNVGIEGLTFWEERRKEVA
RKNSKEQAVVDDSLKF
>Mature_496_residues
MEQLVEWLVGQVWSIGLVVFALGAGVYFTIATRFLQIRYFKEMIKLLFEGKSSETGISSFQAFCLALSGRVGIGNIAGVA
TAIAFGGPGAVFWMWVMALLGAASAFVESTLSQIYKSKVGNEYRGGTPYFIEKGLNMKWFAVIVAVVVTLSYGVLLPGIQ
SSSIAVGFENSNGISKYITGILLVVLLAAIIFGGVKRIAGVSQMLVPFMAIGYVIVTCIVLIANVTEIPSMFALIFSSAF
GVNEMFGGIVGAAIAWGVKRAVFSNVAGVGEATYSSAAAEVSHPAKQGLVQAFSVYIDTIVVCTATALMILITGMYNVIP
EGKSAIVKNIGNVDAGPIYTQQAVETVMTGFGPLFISTAIFFFAFTTLLAYYYIAETTLTYLDRELKHSWLKPVLKIGFL
IMVYIGSVESASLLWNLGDLGIGSMAWLNLIAILLLSKIALKVLKDYETQKKEGKDPVFDPKNVGIEGLTFWEERRKEVA
RKNSKEQAVVDDSLKF

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=461, Percent_Identity=37.527114967462, Blast_Score=278, Evalue=5e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 53547; Mature: 53547

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCHHHHCCCCCC
>Mature Secondary Structure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HCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]