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The map label for this gene is pcoS [H]

Identifier: 52142652

GI number: 52142652

Start: 2707681

End: 2709087

Strand: Reverse

Name: pcoS [H]

Synonym: BCZK2589

Alternate gene names: 52142652

Gene position: 2709087-2707681 (Counterclockwise)

Preceding gene: 52142651

Following gene: 52142655

Centisome position: 51.11

GC content: 30.21

Gene sequence:

>1407_bases
GTGAATAAACTTGGAAAAAAGCTATTTCTTAGTATATCTTTAACCGTTATTCTTATATTTACGATCTCTTTATTATTAAT
TAACTATCTTTTACCGAAATATAATATTTACAAAACACGAGAAAGCTTAGAAGGTATTACAGCGCAAATTCAGTCCATAC
CGAGAGAACAATTGGATGAAGCAATTACGAGCATTGAAAATGAGGGGAATGTTACGATTGCGTATACATCCATAAAAGAC
TCAGAAGATCATATTAATGATGAGTTACGTATGCAACTTACAAAAAAGAGAGTTGCCCTTAATAAAATTTGGATTACAAA
AGAAGAAATAATGAAAGTAAAGAAATTCGGACATTCGAATAAAATATATGATCAAGAGAAAATCAAATCTAGCTTTTTTG
TGAAATACATGGCGAAGGATGATATGTTGATTTTAGTAGGAGTTTCTATCGCACATTCAAATGAAATAATAAAGACGTTA
AACTCATTTTATTTATTCATTTTAGTTATTACGATTTTTCTCATTATCGTACTTGTATGGATATTGTCAAAAACAATTAC
GACACCGCTGAAAGAATTAAGTGATGTCGCAGAAGATATTTCACGTTTACAGTTTAAAAAGACAAAAGTGAAAACGAATG
ATGAAATAGGAGACTTAGCTACTAGTATTAATATCATGAGTGAAAAACTACATGAAGCGCATCAAGATTTAACAGATCGT
AATGAACATTTAAAACGATTTATGGGGGATGTGACGCATGAATTGAAAACTCCAATCGCGTTAGTGAAAGCATATTCTAT
GGGAATAAAAGATGGTCTAGATGACGGTACATACATAGATACAATCATTAAACAATCGGATCACATATCAAACTTAATTG
AAGAGTTATTACGATTTTCTAAACTAGAAAGAGATGTGTTACAAAAAGAAGAATTCTCTATTAAATCACTAGTCCAAAGT
ATATTAGATAAGCATAAGATTGAACTGGAGTCGAGAGAAATTAATTTGCAAGTGAACTATAATGTTGGCGATGCAATTGT
TTATGCAGATGTAAATAAAATGAGAATGGTGTTCCAAAATTTAATTTCTAATGCGATAAAATATACATCAAATCAAAATA
TAAAAATTACATTAGAAGATCGAAATGAGAGTGTATATTTTCAAATTCAAAATGGTATGAATGCTGAACATATGAAAGAT
ATCGATAAAATTTGGGAACCTTTTTACGTCTTAGAATCTTCTCGTAGTAAAGATCGTTCAGGTACAGGACTAGGCTTAGC
GATCGTGAAAAGTATTTTAGAAAGACATGGTTTTGACTATGGCGTATTTACTATAGGGGGAGAAATACGATTTTATATTC
ATATGAAGAATGACTCATTCAATACTAGTAGAAGCATCGTCTATTAA

Upstream 100 bases:

>100_bases
GAGCGAACTGTTGATACACATGTAAGGAGATTACGAAAAAAAGTTGGAGAAAATATTATAAAGACGCACCGCGGGCTAGG
ATATAGTTTGGAGGAACAGA

Downstream 100 bases:

>100_bases
TAGGCGATGTTTTTTTATTGATATATGTAAGTAGTAATTCAAAATATATAACCTTGAAAGCCCGTTGGAAGAGTGTTCTA
CAAATTTCTCAAGTTGTTGT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGITAQIQSIPREQLDEAITSIENEGNVTIAYTSIKD
SEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSNKIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTL
NSFYLFILVITIFLIIVLVWILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLHEAHQDLTDR
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFSKLERDVLQKEEFSIKSLVQS
ILDKHKIELESREINLQVNYNVGDAIVYADVNKMRMVFQNLISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKD
IDKIWEPFYVLESSRSKDRSGTGLGLAIVKSILERHGFDYGVFTIGGEIRFYIHMKNDSFNTSRSIVY

Sequences:

>Translated_468_residues
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGITAQIQSIPREQLDEAITSIENEGNVTIAYTSIKD
SEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSNKIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTL
NSFYLFILVITIFLIIVLVWILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLHEAHQDLTDR
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFSKLERDVLQKEEFSIKSLVQS
ILDKHKIELESREINLQVNYNVGDAIVYADVNKMRMVFQNLISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKD
IDKIWEPFYVLESSRSKDRSGTGLGLAIVKSILERHGFDYGVFTIGGEIRFYIHMKNDSFNTSRSIVY
>Mature_468_residues
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGITAQIQSIPREQLDEAITSIENEGNVTIAYTSIKD
SEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSNKIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTL
NSFYLFILVITIFLIIVLVWILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLHEAHQDLTDR
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFSKLERDVLQKEEFSIKSLVQS
ILDKHKIELESREINLQVNYNVGDAIVYADVNKMRMVFQNLISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKD
IDKIWEPFYVLESSRSKDRSGTGLGLAIVKSILERHGFDYGVFTIGGEIRFYIHMKNDSFNTSRSIVY

Specific function: Probable member of a two-component regulatory system pcoS/pcoR. May activate pcoR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=261, Percent_Identity=26.8199233716475, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790346, Length=193, Percent_Identity=24.3523316062176, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789149, Length=332, Percent_Identity=23.7951807228916, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788279, Length=281, Percent_Identity=27.7580071174377, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786783, Length=322, Percent_Identity=24.5341614906832, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790861, Length=348, Percent_Identity=22.7011494252874, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790551, Length=324, Percent_Identity=25.3086419753086, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI145693157, Length=217, Percent_Identity=25.3456221198157, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786600, Length=218, Percent_Identity=24.3119266055046, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790436, Length=211, Percent_Identity=25.5924170616114, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082128, Length=303, Percent_Identity=22.7722772277228, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI48994928, Length=224, Percent_Identity=23.2142857142857, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788549, Length=274, Percent_Identity=21.8978102189781, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR006290
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53955; Mature: 53955

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGITAQIQSIPREQLDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
AITSIENEGNVTIAYTSIKDSEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSN
HHHHCCCCCCEEEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
KIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTLNSFYLFILVITIFLIIVLVW
CCCCHHHHHHHHHHHEECCCCEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLHEAHQDLTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
KLERDVLQKEEFSIKSLVQSILDKHKIELESREINLQVNYNVGDAIVYADVNKMRMVFQN
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECEEEEEEEEECCCCEEEEECHHHHHHHHHH
LISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKDIDKIWEPFYVLESSRSKDRS
HHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCCC
GTGLGLAIVKSILERHGFDYGVFTIGGEIRFYIHMKNDSFNTSRSIVY
CCCHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGITAQIQSIPREQLDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
AITSIENEGNVTIAYTSIKDSEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSN
HHHHCCCCCCEEEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
KIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTLNSFYLFILVITIFLIIVLVW
CCCCHHHHHHHHHHHEECCCCEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLHEAHQDLTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
KLERDVLQKEEFSIKSLVQSILDKHKIELESREINLQVNYNVGDAIVYADVNKMRMVFQN
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECEEEEEEEEECCCCEEEEECHHHHHHHHHH
LISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKDIDKIWEPFYVLESSRSKDRS
HHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCCC
GTGLGLAIVKSILERHGFDYGVFTIGGEIRFYIHMKNDSFNTSRSIVY
CCCHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8594334 [H]