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The map label for this gene is aroA [H]

Identifier: 52142569

GI number: 52142569

Start: 2786354

End: 2787643

Strand: Reverse

Name: aroA [H]

Synonym: BCZK2673

Alternate gene names: 52142569

Gene position: 2787643-2786354 (Counterclockwise)

Preceding gene: 52142568

Following gene: 52142571

Centisome position: 52.59

GC content: 39.53

Gene sequence:

>1290_bases
GTGAAGGAAAGAACAATACAACCTGTTAATAACGGATTAAATGGCAACATTACAATTCCAGGAGATAAATCGATTTCTCA
CCGCGCTGTCATGTTCGGTGCGATTGCAGAAGGAAAAACAACAATTAAAGGTTTCCTGCCTGGTGCAGACTGTTTAAGTA
CGATTTCTTGTTTTAAAGAAATGGGAGTAGACATTGTGCAAAACGGTGATGAAGTCACTGTAGTTGGTAAAGGATTAGAA
GGTTTACAAGAACCGAAAGCTGTATTAGATGTTGGTAATTCTGGTACAACTATACGTTTAATGTCAGGAATTTTGGCAAA
TACACCATTTTTCTCTTGCGTACAAGGTGATGCGTCTATTGCAAAAAGACCGATGAAACGTGTAACAAATCCATTAAAAC
AAATGGGTGCAAACATTGATGGCCGCGAAGAAGGAACGTTTACACCGCTAACAATACGTGGTGGAGATTTAAAAGCAATT
GAATACACTTCCCCGGTAGCAAGCGCACAAGTGAAATCAGCTATTTTACTTGCAGGACTTCGTGCAGAAGGTGTAACAGC
TGTTACAGAACCACATATTTCTCGCGATCATACGGAAAGAATGCTTGAAGCATTTGGCGTCAAAGTAACTCGCGAAGGGA
AAACAGTGAAACTAGCAGGTGGACAAAAGTTAACAGCGACAGATGTTCAAGTGCCCGGCGACGTATCATCAGCTGCATTT
TTCTTAGTAGCGGGCGCGATTATTCCAAATAGTAAACTAGTATTAGAAAATGTAGGGATGAATCCAACTCGTACAGGTAT
TATTGATGTTTTAGAGAAGATGGGTGCTACATTTACTGTAGAGCCAATTAACGAAGGTGCATCAGAACCAGCTGCAAACA
TTACAATTGAAACATCTTCATTAAAAGGAATCGAAATCGGCGGAGATATTATCCCAAGATTAATCGATGAAATTCCTGTA
ATTGCATTAGCGGCAACGCAAGCAGAAGGAATTACAGTTATTAAAGATGCACACGAATTAAAAGTAAAAGAGACAAACCG
TATTGATACAGTTGTTGCAGAGTTAACGAAACTAGGAGCTCGTATAGAAGCAACCGATGACGGAATGATCATTTACGGGA
AATCAGTTTTAAAAGGAAATACAGTTAATAGTTATGGTGATCACCGCATCGGAATGATGCTTGCGATTGCCGGTTGTCTA
GCAGAAGGTAAAACAACAATTGAAGACGCAGAAGCAGTAGGTGTATCATACCCTACATTCTTCGAAGAACTTCAAAAGTT
AGCTAAATAA

Upstream 100 bases:

>100_bases
ATTAGCTTCCAACGAGAAGAAGATCGTATGAAAGCAAAGCTAGCGCTTGGAGAAGAAAAATACGAAACTTATGAAACAAT
TTAAATGAGAAGGTGAAAAC

Downstream 100 bases:

>100_bases
GGTGAAACTTTAATCAGTGGGGGGTTCTTCATCCCCCACTGATTATCAGCCCTCACCAATCGGGCTTTTACGGGCAGTTG
ATCCCATACCTAAATTCTTT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGAIAEGKTTIKGFLPGADCLSTISCFKEMGVDIVQNGDEVTVVGKGLE
GLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDASIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAI
EYTSPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPV
IALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSVLKGNTVNSYGDHRIGMMLAIAGCL
AEGKTTIEDAEAVGVSYPTFFEELQKLAK

Sequences:

>Translated_429_residues
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGAIAEGKTTIKGFLPGADCLSTISCFKEMGVDIVQNGDEVTVVGKGLE
GLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDASIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAI
EYTSPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPV
IALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSVLKGNTVNSYGDHRIGMMLAIAGCL
AEGKTTIEDAEAVGVSYPTFFEELQKLAK
>Mature_429_residues
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGAIAEGKTTIKGFLPGADCLSTISCFKEMGVDIVQNGDEVTVVGKGLE
GLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDASIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAI
EYTSPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPV
IALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSVLKGNTVNSYGDHRIGMMLAIAGCL
AEGKTTIEDAEAVGVSYPTFFEELQKLAK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=443, Percent_Identity=28.6681715575621, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320332, Length=457, Percent_Identity=25.382932166302, Blast_Score=102, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 45213; Mature: 45213

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGAIAEGKTTIKGFLPGADCLSTISCFKE
CCCCCCCHHCCCCCCCEECCCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHH
MGVDIVQNGDEVTVVGKGLEGLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDASI
CCCCEEECCCEEEEEECCCCCHHCCHHHEECCCCCCEEHHHHHHHHCCCCCEEECCCHHH
AKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAIEYTSPVASAQVKSAILLAGL
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCC
RAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
CCCCCEEECCCCCCHHHHHHHHHHHCCEEECCCCEEEEECCCEEEEECEECCCCCHHHHH
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSS
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEECC
LKGIEIGGDIIPRLIDEIPVIALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGA
CCCEEECHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHEEECCCCHHHHHHHHHHHHCC
RIEATDDGMIIYGKSVLKGNTVNSYGDHRIGMMLAIAGCLAEGKTTIEDAEAVGVSYPTF
EEEECCCCEEEEECCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHH
FEELQKLAK
HHHHHHHCC
>Mature Secondary Structure
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGAIAEGKTTIKGFLPGADCLSTISCFKE
CCCCCCCHHCCCCCCCEECCCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHH
MGVDIVQNGDEVTVVGKGLEGLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDASI
CCCCEEECCCEEEEEECCCCCHHCCHHHEECCCCCCEEHHHHHHHHCCCCCEEECCCHHH
AKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAIEYTSPVASAQVKSAILLAGL
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCC
RAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
CCCCCEEECCCCCCHHHHHHHHHHHCCEEECCCCEEEEECCCEEEEECEECCCCCHHHHH
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSS
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEECC
LKGIEIGGDIIPRLIDEIPVIALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGA
CCCEEECHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHEEECCCCHHHHHHHHHHHHCC
RIEATDDGMIIYGKSVLKGNTVNSYGDHRIGMMLAIAGCLAEGKTTIEDAEAVGVSYPTF
EEEECCCCEEEEECCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHH
FEELQKLAK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA