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The map label for this gene is stc [H]

Identifier: 52142552

GI number: 52142552

Start: 2806355

End: 2807155

Strand: Reverse

Name: stc [H]

Synonym: BCZK2689

Alternate gene names: 52142552

Gene position: 2807155-2806355 (Counterclockwise)

Preceding gene: 52142553

Following gene: 52142555

Centisome position: 52.96

GC content: 38.2

Gene sequence:

>801_bases
TTGAATTGTGCTGCGATTCCGAGAGATCTTTTGGAAGCTGAATTATTTGGATACGAAGAAGGGGCTTTTACAGGAGCGAA
AAAAGGTGGTAAGCCTGGGAAGATTGAGTTAGCCGAAAAGGGAACGTTATTCTTAGATGAAATTGGTGATATGTCTTTGG
ACATGCAAGTGAAGCTACTTCGTGTATTGCAAGAGAAAGAGATTGAAAGAATTGGCGGTACGAAAATTCAAAAGGTTGAT
GTTCGTTTCATTGCGGCGACACATCGAAATCTCCGTGAAATGGTGCAAAGAGGGGAGTTCAGAGAGGATTTATATTATAG
GTTGAATGTGTTTGAGATTGCTATTCCTCCGTTACGAGAGAGAAAAGAAGATATGATACATATAACGGAATTTTTAATTA
AGAAATTGAATGGTGAGCTAGGTAGTAACGTTATTTCATTTGATGAGAGAGTTAGAGAGATATTCATGGAGCATGATTGG
CCAGGGAATATTAGGGAGCTAGAAAATGTATTAGAACGAGCGATGAATGTTATAGAAGGAATGATTATTCAAGTGCATCA
TCTTCCGGCCTATTTACGGAAAAAAGATAAGGAAGAAGAGTTATACCATGACATATTTACGATAGATCAAAAACAGAATG
AGGGGGAGTATTCACTTCAGGCGGAAGTGGAATCCGCTGAAAAACGTGCGATTACGAGAGCTTTGGAAAAAACAGCTGGA
AATATAAAAGAGGCAGCCAGGCTTTTAGGAATTCATCGGGCTAGCTTATATCGAAAAATAGAAAAATATGAAATATCATG
A

Upstream 100 bases:

>100_bases
AAAATGAAAGAAGTCAAGAGGAGAGAGTGGTACGGGAAAGGAACTCTTTGCACATGCGGTACACCGTGCAAGTCCGCGTG
CTAGTGGTACATTTATTCGT

Downstream 100 bases:

>100_bases
AGGAAAGTAAAGGGCAAACAGGCCCTTTTTTTGTTTGTAGTAATAAATACTGTCTCTTTTTTGCGACGTTTTCTTATAGA
TGCGACATGGTTGCTAATAT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MNCAAIPRDLLEAELFGYEEGAFTGAKKGGKPGKIELAEKGTLFLDEIGDMSLDMQVKLLRVLQEKEIERIGGTKIQKVD
VRFIAATHRNLREMVQRGEFREDLYYRLNVFEIAIPPLRERKEDMIHITEFLIKKLNGELGSNVISFDERVREIFMEHDW
PGNIRELENVLERAMNVIEGMIIQVHHLPAYLRKKDKEEELYHDIFTIDQKQNEGEYSLQAEVESAEKRAITRALEKTAG
NIKEAARLLGIHRASLYRKIEKYEIS

Sequences:

>Translated_266_residues
MNCAAIPRDLLEAELFGYEEGAFTGAKKGGKPGKIELAEKGTLFLDEIGDMSLDMQVKLLRVLQEKEIERIGGTKIQKVD
VRFIAATHRNLREMVQRGEFREDLYYRLNVFEIAIPPLRERKEDMIHITEFLIKKLNGELGSNVISFDERVREIFMEHDW
PGNIRELENVLERAMNVIEGMIIQVHHLPAYLRKKDKEEELYHDIFTIDQKQNEGEYSLQAEVESAEKRAITRALEKTAG
NIKEAARLLGIHRASLYRKIEKYEIS
>Mature_266_residues
MNCAAIPRDLLEAELFGYEEGAFTGAKKGGKPGKIELAEKGTLFLDEIGDMSLDMQVKLLRVLQEKEIERIGGTKIQKVD
VRFIAATHRNLREMVQRGEFREDLYYRLNVFEIAIPPLRERKEDMIHITEFLIKKLNGELGSNVISFDERVREIFMEHDW
PGNIRELENVLERAMNVIEGMIIQVHHLPAYLRKKDKEEELYHDIFTIDQKQNEGEYSLQAEVESAEKRAITRALEKTAG
NIKEAARLLGIHRASLYRKIEKYEIS

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=267, Percent_Identity=44.9438202247191, Blast_Score=221, Evalue=3e-59,
Organism=Escherichia coli, GI1789233, Length=266, Percent_Identity=44.7368421052632, Blast_Score=215, Evalue=2e-57,
Organism=Escherichia coli, GI1789087, Length=268, Percent_Identity=44.7761194029851, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1790437, Length=262, Percent_Identity=45.4198473282443, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI87082117, Length=269, Percent_Identity=41.2639405204461, Blast_Score=203, Evalue=8e-54,
Organism=Escherichia coli, GI1790299, Length=272, Percent_Identity=41.9117647058824, Blast_Score=200, Evalue=7e-53,
Organism=Escherichia coli, GI1786524, Length=269, Percent_Identity=40.1486988847584, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI1788905, Length=265, Percent_Identity=38.4905660377359, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI87082152, Length=264, Percent_Identity=39.0151515151515, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI1787583, Length=268, Percent_Identity=35.0746268656716, Blast_Score=163, Evalue=8e-42,
Organism=Escherichia coli, GI87081872, Length=176, Percent_Identity=46.0227272727273, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI87081858, Length=270, Percent_Identity=32.962962962963, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1789828, Length=179, Percent_Identity=35.195530726257, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 30843; Mature: 30843

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCAAIPRDLLEAELFGYEEGAFTGAKKGGKPGKIELAEKGTLFLDEIGDMSLDMQVKLL
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEHHHCCCCHHHHHHHH
RVLQEKEIERIGGTKIQKVDVRFIAATHRNLREMVQRGEFREDLYYRLNVFEIAIPPLRE
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEECCCHHH
RKEDMIHITEFLIKKLNGELGSNVISFDERVREIFMEHDWPGNIRELENVLERAMNVIEG
HHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
MIIQVHHLPAYLRKKDKEEELYHDIFTIDQKQNEGEYSLQAEVESAEKRAITRALEKTAG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHC
NIKEAARLLGIHRASLYRKIEKYEIS
CHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNCAAIPRDLLEAELFGYEEGAFTGAKKGGKPGKIELAEKGTLFLDEIGDMSLDMQVKLL
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEHHHCCCCHHHHHHHH
RVLQEKEIERIGGTKIQKVDVRFIAATHRNLREMVQRGEFREDLYYRLNVFEIAIPPLRE
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEECCCHHH
RKEDMIHITEFLIKKLNGELGSNVISFDERVREIFMEHDWPGNIRELENVLERAMNVIEG
HHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
MIIQVHHLPAYLRKKDKEEELYHDIFTIDQKQNEGEYSLQAEVESAEKRAITRALEKTAG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHC
NIKEAARLLGIHRASLYRKIEKYEIS
CHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA