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The map label for this gene is argD [H]

Identifier: 52142496

GI number: 52142496

Start: 2864141

End: 2865358

Strand: Reverse

Name: argD [H]

Synonym: BCZK2746

Alternate gene names: 52142496

Gene position: 2865358-2864141 (Counterclockwise)

Preceding gene: 52142494

Following gene: 52142497

Centisome position: 54.05

GC content: 34.48

Gene sequence:

>1218_bases
ATGTCGGATTGGTTTCAATTAGATAAAGAATATATGGTGCCTACGTACTGTCGTACGAAGGTCGCGATTGAAAGAGGAGA
AGGATGTAAACTATATGATGTGGACGGTAAAGAGTATATAGATTTATTTTCTGGTGTCGGAGTGAACGTATTAGGATACA
ATCACCCGAAAATCGTGCAAGCGACAATGGATCAAGTTACGAAGTCGTTGCATCTACCGTTTCATTTTTTAAATCCAGTT
GCGATTGAGTATGCAAAGAAATTAGTTGAATGCTCTGTAAAAAACGGAAAGGTCTTTTTCACAAACTCAGGTACGGAAGC
GACAGAAACGACATTAAAATTAATTGATAAATATAGAGCTATTACACATGAAGAACGTGAAGGAATTGTAGTGCTGAAGA
ATAGTTTCCACGGGCGTACGTTAGGAGCACTTCATTTTACGAGACAAGAAAGTGTATATCAAAATTTTCCTAAAACATCG
ATCCCAGTATATGAAGTTGAGCGTGAGAATATAGAGCAATTAGAAGAAACAATAATTGATGAAAATCCAATTGCGATTCT
GTTAGAACCTGTATTAGGAAGCGGGGGTATTTATCCTTTATCGCGTGAATATTTACATGGTGTTCAAAAATTATGTGATA
AATATAATATCATTCTAATCGTTGATGAAGTGCAAAGTGGTATGGGGAGAACAGGAAAACTTTTTGCTTATCAAAATTTC
AATATTACACCACATGTTATTCAAATTGGTAAAGGAGCAGGAGGCGGGATACCGCTAGGTGGAATTATTGTAGGTGAAAA
GTTATGTGATGTATTTGCGCCAGGAGATCACGGTACAACGTTTGCTCATTCATCAATGGGAACTGCTTTAGGTTTAACAG
TATTAAATACATTACTTGACGATAGTTTCATGCAAGAAGCATATGAAACGTCACTTTATTTAAATGATAAATTGCAAGAA
ATTCAAAAAGAAAATTCTTATTATATTGAGGAAGTACGTCATGCTGGTATGATGTTTGGAATTAGTTTGAATGATACAAA
TGAAAATGTGAAGAAATTACAGGTAGAGCTAATGGAGAAAGGAATTTTAGTTGACGTAACACAAGGGAATATCATCCGTT
TACTTCCTCCATATATAATTACAAAAGAAGAAATTGATACATTTATTACTCAATTTATTTTTTGTATGGATAAAGTTGCT
GCTGTAGTAAGTGCTTAA

Upstream 100 bases:

>100_bases
AATATCGGGAAGAACATTACTATTAAAATTTCAATCTTAAAAATGAATTTATAGAGAATGAGTATAAATAAACAGGGAAA
ATAACTAGGAGGAATGTAAC

Downstream 100 bases:

>100_bases
AAGTTAAAAGCTATATGTTATATAAAGTGCACTCTAATTGTTAGGGATATTTTTACAATTGGGGTGCATTTTTATAATTA
AATTTTGTAAAATACAGTCG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSDWFQLDKEYMVPTYCRTKVAIERGEGCKLYDVDGKEYIDLFSGVGVNVLGYNHPKIVQATMDQVTKSLHLPFHFLNPV
AIEYAKKLVECSVKNGKVFFTNSGTEATETTLKLIDKYRAITHEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPKTS
IPVYEVERENIEQLEETIIDENPIAILLEPVLGSGGIYPLSREYLHGVQKLCDKYNIILIVDEVQSGMGRTGKLFAYQNF
NITPHVIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLDDSFMQEAYETSLYLNDKLQE
IQKENSYYIEEVRHAGMMFGISLNDTNENVKKLQVELMEKGILVDVTQGNIIRLLPPYIITKEEIDTFITQFIFCMDKVA
AVVSA

Sequences:

>Translated_405_residues
MSDWFQLDKEYMVPTYCRTKVAIERGEGCKLYDVDGKEYIDLFSGVGVNVLGYNHPKIVQATMDQVTKSLHLPFHFLNPV
AIEYAKKLVECSVKNGKVFFTNSGTEATETTLKLIDKYRAITHEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPKTS
IPVYEVERENIEQLEETIIDENPIAILLEPVLGSGGIYPLSREYLHGVQKLCDKYNIILIVDEVQSGMGRTGKLFAYQNF
NITPHVIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLDDSFMQEAYETSLYLNDKLQE
IQKENSYYIEEVRHAGMMFGISLNDTNENVKKLQVELMEKGILVDVTQGNIIRLLPPYIITKEEIDTFITQFIFCMDKVA
AVVSA
>Mature_404_residues
SDWFQLDKEYMVPTYCRTKVAIERGEGCKLYDVDGKEYIDLFSGVGVNVLGYNHPKIVQATMDQVTKSLHLPFHFLNPVA
IEYAKKLVECSVKNGKVFFTNSGTEATETTLKLIDKYRAITHEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPKTSI
PVYEVERENIEQLEETIIDENPIAILLEPVLGSGGIYPLSREYLHGVQKLCDKYNIILIVDEVQSGMGRTGKLFAYQNFN
ITPHVIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLDDSFMQEAYETSLYLNDKLQEI
QKENSYYIEEVRHAGMMFGISLNDTNENVKKLQVELMEKGILVDVTQGNIIRLLPPYIITKEEIDTFITQFIFCMDKVAA
VVSA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=389, Percent_Identity=29.305912596401, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI284507298, Length=290, Percent_Identity=28.2758620689655, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI13994255, Length=443, Percent_Identity=24.3792325056433, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI37574042, Length=448, Percent_Identity=23.6607142857143, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI226442705, Length=448, Percent_Identity=23.2142857142857, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI226442709, Length=396, Percent_Identity=23.989898989899, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI188536080, Length=427, Percent_Identity=22.248243559719, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI38679950, Length=427, Percent_Identity=22.248243559719, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI38679946, Length=427, Percent_Identity=22.248243559719, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1788044, Length=387, Percent_Identity=33.8501291989664, Blast_Score=251, Evalue=5e-68,
Organism=Escherichia coli, GI1789759, Length=392, Percent_Identity=28.3163265306122, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI145693181, Length=375, Percent_Identity=32.2666666666667, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1789016, Length=412, Percent_Identity=30.0970873786408, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1787560, Length=395, Percent_Identity=30.6329113924051, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1786991, Length=383, Percent_Identity=27.154046997389, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786349, Length=345, Percent_Identity=28.9855072463768, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=386, Percent_Identity=30.0518134715026, Blast_Score=197, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI25144274, Length=265, Percent_Identity=30.188679245283, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI32564660, Length=424, Percent_Identity=26.4150943396226, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71992977, Length=409, Percent_Identity=22.4938875305623, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17541228, Length=437, Percent_Identity=21.9679633867277, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71981843, Length=182, Percent_Identity=26.3736263736264, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324432, Length=408, Percent_Identity=33.0882352941176, Blast_Score=219, Evalue=5e-58,
Organism=Saccharomyces cerevisiae, GI6323470, Length=411, Percent_Identity=27.9805352798054, Blast_Score=180, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6324386, Length=434, Percent_Identity=25.3456221198157, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=418, Percent_Identity=22.9665071770335, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21357415, Length=401, Percent_Identity=30.9226932668329, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI161085790, Length=435, Percent_Identity=24.8275862068966, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28574759, Length=414, Percent_Identity=25.3623188405797, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356575, Length=428, Percent_Identity=23.1308411214953, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281366494, Length=428, Percent_Identity=24.2990654205607, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24667139, Length=428, Percent_Identity=24.2990654205607, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24667143, Length=428, Percent_Identity=24.2990654205607, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 45371; Mature: 45239

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDWFQLDKEYMVPTYCRTKVAIERGEGCKLYDVDGKEYIDLFSGVGVNVLGYNHPKIVQ
CCCHHHCCCCCCCCHHHHHEEEEECCCCCEEEECCCHHHHHHHCCCCEEEEECCCCHHHH
ATMDQVTKSLHLPFHFLNPVAIEYAKKLVECSVKNGKVFFTNSGTEATETTLKLIDKYRA
HHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHH
ITHEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPKTSIPVYEVERENIEQLEETIID
HCCCCCCCEEEEECCCCCCEEEHEEEHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHCC
ENPIAILLEPVLGSGGIYPLSREYLHGVQKLCDKYNIILIVDEVQSGMGRTGKLFAYQNF
CCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCEEEEEECC
NITPHVIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLD
CCCCEEEEECCCCCCCCCCCCEEHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHH
DSFMQEAYETSLYLNDKLQEIQKENSYYIEEVRHAGMMFGISLNDTNENVKKLQVELMEK
HHHHHHHHHHHEEECHHHHHHHHCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHC
GILVDVTQGNIIRLLPPYIITKEEIDTFITQFIFCMDKVAAVVSA
CCEEEECCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDWFQLDKEYMVPTYCRTKVAIERGEGCKLYDVDGKEYIDLFSGVGVNVLGYNHPKIVQ
CCHHHCCCCCCCCHHHHHEEEEECCCCCEEEECCCHHHHHHHCCCCEEEEECCCCHHHH
ATMDQVTKSLHLPFHFLNPVAIEYAKKLVECSVKNGKVFFTNSGTEATETTLKLIDKYRA
HHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHH
ITHEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPKTSIPVYEVERENIEQLEETIID
HCCCCCCCEEEEECCCCCCEEEHEEEHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHCC
ENPIAILLEPVLGSGGIYPLSREYLHGVQKLCDKYNIILIVDEVQSGMGRTGKLFAYQNF
CCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCEEEEEECC
NITPHVIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLD
CCCCEEEEECCCCCCCCCCCCEEHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHH
DSFMQEAYETSLYLNDKLQEIQKENSYYIEEVRHAGMMFGISLNDTNENVKKLQVELMEK
HHHHHHHHHHHEEECHHHHHHHHCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHC
GILVDVTQGNIIRLLPPYIITKEEIDTFITQFIFCMDKVAAVVSA
CCEEEECCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]