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The map label for this gene is ade [C]

Identifier: 52142489

GI number: 52142489

Start: 2872242

End: 2874011

Strand: Reverse

Name: ade [C]

Synonym: BCZK2753

Alternate gene names: 52142489

Gene position: 2874011-2872242 (Counterclockwise)

Preceding gene: 52142487

Following gene: 52142490

Centisome position: 54.22

GC content: 35.54

Gene sequence:

>1770_bases
TTGGAGTTGAATAAAGTGGAACAAAAGTATTTCAGATGGAGTAACGAGCAATTACGAGAACATGTTGAAATAATAGACGG
TACAAGAAGTCCTCATAAATTATTAAAGAACGCAACATACTTAAATTCCTATATACGTGAATGGATGCAAGCAAATATTT
GGATCTATGATGACAGAATTATATATGTAGGAGAAAAACTACCAGAGCAATTACATGAATGTGAAGTCATTGATTGTGAT
GGAAAGTATGTCGTTCCTAGTTACATAGAGCCACATGCACATCCGTATCAATTATATAATCCAGAGACATTAGCGAATCA
TGCGATGCAATTTGGGACAACAACTTTTATTAATGATAATTTAACTTTATTTTTCACATTAAAGCGTGAAGAATCATTTC
ATTTATTAGATGAATTTACAAAGATTCCAGCTAGTATGTATTGGTGGTGTCGTTTTGATGGACAAACTGAATTGCAAAAC
GGGGAATCTTTATTTAATAGTGAAGAAATAATAAAGTGGCTACAGCATGAAGCAGTTCTGCAAGGCGGCGAGTTAACAGC
ATGGCCAAAATTATTACATGGCGATGATGAAATGTTAAATTGGGTGCAGGAAACAAAGCGATTACAGAAAAAAGTGGAAG
GACATTTCCCAGGAGCATCTGAAGCAACGTTAGTGAAATTAAAACTGTTAGGTACGGATTGCGATCATGAAGCGATGACA
GGGCAAGAAGCGTTAGCTCGTCTTATGCAAGGTTACACCGTTTCTCTTAGGAATTCTTCCATACGCACAGATTTAGAAGT
TTTATTGAAGGAATTGTTGGAATTAGGTGTTAAGCAGTTTGATAGATTCATTTTTACAACAGACGGTTCACATCCGTCCT
TTTATGAAAACGGAATGACGAATATCATGATTGCTACCGCTATAAAGAAAGGTATTCCAGTAATTGATGCGTATCAAATG
GCAAGTTATAATATTGCTCGTTATTATAATATGGAGCATGTACATGGTTCAATTGCGACAGGTAGAATTGCTAATATCAA
TATTTTAGAAAGTAAAGAAAACCCAGTGCCAACGAGCGTAATTGCAAAGGGACAATGGGTAAAGCGTGACGGTGTAAATA
CACATGAATTATTACATATAGACTGGAGTAAATGTAAAGTAACTCCATTATCATTAGATTGGTCGATAGAAAAAGAGGAT
ATGCTTTTTTCTAATAAAACGGGTATCCACTTATTAAATAACGTTATAACAAAACCATATACTAGTGAAATTAACATAGA
CTGTGATGAATTGTCCATAGATCATGATGAATGTTTCCTTATGATGATTGCTCGTGATGGTACTTGGCGAGTGAATACAG
TTGTAAAAGGTTTTGCGAAAGAACTAGGAGGCCTTGCTAGCTCTTATTCTGGTACGGGTGACATCATTCTTGTCGGGAAG
AGAAAAGAAGATATGCTTACAGCTTTTTATAGAGTAAAAGAGCTCGGCGGCGGAATGGTAATCGCGGAAAAAAATGAAGT
GTTGCATGAAATTAAATTACCATTACTCGGGATTATGTCTAATTTAAAAATGAGTGAATTAATACAAGAAGAGAAACAGA
TGGTGAAATTACTACAAGAGCGAGGTTACGCATATAACGATCCAGCATTTACGATTTTATTCTTTTCTGCGACGCATTTG
CCTTTTATAAGGGTAACGCCTATAGGGCTATATGATGTAAAAAGTGGAAAGGTAGTTACTTCGCCGGTGAATTTGATAAA
GCAATATTAG

Upstream 100 bases:

>100_bases
ATTTTTGTGATTGTTAAATATAATAGGGGTACATATCGAGTGAGCTTGAATGGAAAATAGTTTAGTTGATTAATTATTTT
TCATCTTAATTAATATAGCA

Downstream 100 bases:

>100_bases
AAAGAACTCCTCCGCTACAGTAGTTATGTAAAGTGGGGGAGTTTTACATTTTAGATGTATTGTTATAATTGGGGTTACAT
ATAAATAATCTCAAAAATAT

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase [H]

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MELNKVEQKYFRWSNEQLREHVEIIDGTRSPHKLLKNATYLNSYIREWMQANIWIYDDRIIYVGEKLPEQLHECEVIDCD
GKYVVPSYIEPHAHPYQLYNPETLANHAMQFGTTTFINDNLTLFFTLKREESFHLLDEFTKIPASMYWWCRFDGQTELQN
GESLFNSEEIIKWLQHEAVLQGGELTAWPKLLHGDDEMLNWVQETKRLQKKVEGHFPGASEATLVKLKLLGTDCDHEAMT
GQEALARLMQGYTVSLRNSSIRTDLEVLLKELLELGVKQFDRFIFTTDGSHPSFYENGMTNIMIATAIKKGIPVIDAYQM
ASYNIARYYNMEHVHGSIATGRIANINILESKENPVPTSVIAKGQWVKRDGVNTHELLHIDWSKCKVTPLSLDWSIEKED
MLFSNKTGIHLLNNVITKPYTSEINIDCDELSIDHDECFLMMIARDGTWRVNTVVKGFAKELGGLASSYSGTGDIILVGK
RKEDMLTAFYRVKELGGGMVIAEKNEVLHEIKLPLLGIMSNLKMSELIQEEKQMVKLLQERGYAYNDPAFTILFFSATHL
PFIRVTPIGLYDVKSGKVVTSPVNLIKQY

Sequences:

>Translated_589_residues
MELNKVEQKYFRWSNEQLREHVEIIDGTRSPHKLLKNATYLNSYIREWMQANIWIYDDRIIYVGEKLPEQLHECEVIDCD
GKYVVPSYIEPHAHPYQLYNPETLANHAMQFGTTTFINDNLTLFFTLKREESFHLLDEFTKIPASMYWWCRFDGQTELQN
GESLFNSEEIIKWLQHEAVLQGGELTAWPKLLHGDDEMLNWVQETKRLQKKVEGHFPGASEATLVKLKLLGTDCDHEAMT
GQEALARLMQGYTVSLRNSSIRTDLEVLLKELLELGVKQFDRFIFTTDGSHPSFYENGMTNIMIATAIKKGIPVIDAYQM
ASYNIARYYNMEHVHGSIATGRIANINILESKENPVPTSVIAKGQWVKRDGVNTHELLHIDWSKCKVTPLSLDWSIEKED
MLFSNKTGIHLLNNVITKPYTSEINIDCDELSIDHDECFLMMIARDGTWRVNTVVKGFAKELGGLASSYSGTGDIILVGK
RKEDMLTAFYRVKELGGGMVIAEKNEVLHEIKLPLLGIMSNLKMSELIQEEKQMVKLLQERGYAYNDPAFTILFFSATHL
PFIRVTPIGLYDVKSGKVVTSPVNLIKQY
>Mature_589_residues
MELNKVEQKYFRWSNEQLREHVEIIDGTRSPHKLLKNATYLNSYIREWMQANIWIYDDRIIYVGEKLPEQLHECEVIDCD
GKYVVPSYIEPHAHPYQLYNPETLANHAMQFGTTTFINDNLTLFFTLKREESFHLLDEFTKIPASMYWWCRFDGQTELQN
GESLFNSEEIIKWLQHEAVLQGGELTAWPKLLHGDDEMLNWVQETKRLQKKVEGHFPGASEATLVKLKLLGTDCDHEAMT
GQEALARLMQGYTVSLRNSSIRTDLEVLLKELLELGVKQFDRFIFTTDGSHPSFYENGMTNIMIATAIKKGIPVIDAYQM
ASYNIARYYNMEHVHGSIATGRIANINILESKENPVPTSVIAKGQWVKRDGVNTHELLHIDWSKCKVTPLSLDWSIEKED
MLFSNKTGIHLLNNVITKPYTSEINIDCDELSIDHDECFLMMIARDGTWRVNTVVKGFAKELGGLASSYSGTGDIILVGK
RKEDMLTAFYRVKELGGGMVIAEKNEVLHEIKLPLLGIMSNLKMSELIQEEKQMVKLLQERGYAYNDPAFTILFFSATHL
PFIRVTPIGLYDVKSGKVVTSPVNLIKQY

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=603, Percent_Identity=22.7197346600332, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 67535; Mature: 67535

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELNKVEQKYFRWSNEQLREHVEIIDGTRSPHKLLKNATYLNSYIREWMQANIWIYDDRI
CCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECEE
IYVGEKLPEQLHECEVIDCDGKYVVPSYIEPHAHPYQLYNPETLANHAMQFGTTTFINDN
EEECHHHHHHHHCCEEEECCCCEECCCCCCCCCCCEEECCCHHHHHHHHHHCCEEEECCC
LTLFFTLKREESFHLLDEFTKIPASMYWWCRFDGQTELQNGESLFNSEEIIKWLQHEAVL
EEEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHH
QGGELTAWPKLLHGDDEMLNWVQETKRLQKKVEGHFPGASEATLVKLKLLGTDCDHEAMT
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHCC
GQEALARLMQGYTVSLRNSSIRTDLEVLLKELLELGVKQFDRFIFTTDGSHPSFYENGMT
CHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHCCCC
NIMIATAIKKGIPVIDAYQMASYNIARYYNMEHVHGSIATGRIANINILESKENPVPTSV
CEEEEEHHHHCCCEEEHHHHHCCCCHHEECHHHHCCCCCCCCEEEEEEEECCCCCCCHHH
IAKGQWVKRDGVNTHELLHIDWSKCKVTPLSLDWSIEKEDMLFSNKTGIHLLNNVITKPY
CCCCCEEECCCCCCEEEEEEEHHHEEEEEEEECCCCCHHHHEECCCCCHHHHHHHHCCCC
TSEINIDCDELSIDHDECFLMMIARDGTWRVNTVVKGFAKELGGLASSYSGTGDIILVGK
CCCCCCCHHHCCCCCCCEEEEEEECCCCEEHHHHHHHHHHHHCCHHHCCCCCCCEEEEEC
RKEDMLTAFYRVKELGGGMVIAEKNEVLHEIKLPLLGIMSNLKMSELIQEEKQMVKLLQE
CCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RGYAYNDPAFTILFFSATHLPFIRVTPIGLYDVKSGKVVTSPVNLIKQY
CCCEECCCCEEEEEEECCCCCEEEEECCEEEECCCCCEEECHHHHHHCC
>Mature Secondary Structure
MELNKVEQKYFRWSNEQLREHVEIIDGTRSPHKLLKNATYLNSYIREWMQANIWIYDDRI
CCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECEE
IYVGEKLPEQLHECEVIDCDGKYVVPSYIEPHAHPYQLYNPETLANHAMQFGTTTFINDN
EEECHHHHHHHHCCEEEECCCCEECCCCCCCCCCCEEECCCHHHHHHHHHHCCEEEECCC
LTLFFTLKREESFHLLDEFTKIPASMYWWCRFDGQTELQNGESLFNSEEIIKWLQHEAVL
EEEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHH
QGGELTAWPKLLHGDDEMLNWVQETKRLQKKVEGHFPGASEATLVKLKLLGTDCDHEAMT
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHCC
GQEALARLMQGYTVSLRNSSIRTDLEVLLKELLELGVKQFDRFIFTTDGSHPSFYENGMT
CHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHCCCC
NIMIATAIKKGIPVIDAYQMASYNIARYYNMEHVHGSIATGRIANINILESKENPVPTSV
CEEEEEHHHHCCCEEEHHHHHCCCCHHEECHHHHCCCCCCCCEEEEEEEECCCCCCCHHH
IAKGQWVKRDGVNTHELLHIDWSKCKVTPLSLDWSIEKEDMLFSNKTGIHLLNNVITKPY
CCCCCEEECCCCCCEEEEEEEHHHEEEEEEEECCCCCHHHHEECCCCCHHHHHHHHCCCC
TSEINIDCDELSIDHDECFLMMIARDGTWRVNTVVKGFAKELGGLASSYSGTGDIILVGK
CCCCCCCHHHCCCCCCCEEEEEEECCCCEEHHHHHHHHHHHHCCHHHCCCCCCCEEEEEC
RKEDMLTAFYRVKELGGGMVIAEKNEVLHEIKLPLLGIMSNLKMSELIQEEKQMVKLLQE
CCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RGYAYNDPAFTILFFSATHLPFIRVTPIGLYDVKSGKVVTSPVNLIKQY
CCCEECCCCEEEEEEECCCCCEEEEECCEEEECCCCCEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]