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The map label for this gene is tipA [H]

Identifier: 52142445

GI number: 52142445

Start: 2912971

End: 2913738

Strand: Reverse

Name: tipA [H]

Synonym: BCZK2797

Alternate gene names: 52142445

Gene position: 2913738-2912971 (Counterclockwise)

Preceding gene: 52142444

Following gene: 52142450

Centisome position: 54.97

GC content: 32.03

Gene sequence:

>768_bases
ATGAAAAAGGATAAAAAGTTTTCTATCGGAGAATTCTCAGAAAAAACGGGAATACCAATTCCTACTTTGCACTATTATGA
TGAAATCGGGTTATTACAACCTGAAAAGAACCCTGCCTCAGGGCACCGCATTTATAAATATCAAGATATTATAACCTTAC
AAAAAATTCTAAGTTTAAAATTTCTAGGCTATAGTCTAGATAAAGTCGCTAATTTATTACACGAATCAAGTTTTGGTGTT
GATTTGAATGAAAGTTTGTCTCTCCATTTGCAAGTGTTAGAAAGAGAACAAGAACAAATTGAGCAATCAATGCAAGCAAT
GAAAAGAGTAATGAAGTTAGTCGAAGAGGAATGTGAAATAGATAGTACAGTATTATTTAGTCTTATTTACGGTATGAATA
CAGAACATACACATAAAGAATGGATGAAACGTCATGGGTTAACGGATATCGTGGAAGAATTATCAAAGAAACGAGAAGAA
GATAAAATTGCTTTGGATCAAACGTTTATTCAATTGTCTAAAAAGGTTAAACAATTATATGGTAAACCAGTCGAGGATTC
GAAAGTACAAGAGATGGTAAAGGAATATATAGAAGAGTCTTTTTCATTTCTTAGTGAAGATTTGATACAAAAATTAGCTA
ATACTAGTGTGGAAGAACTGGATATGCAAGAACTTGAAAATATGATACCTTCGCCTTTCACAGAAGATGAACAAAAATGG
CTTAATGAAGCGATGGAATATTATGTGAAGCAAGTAGAAATGGAATAG

Upstream 100 bases:

>100_bases
CATGCATTTTAACGTTTTTGAATTTTCTTGAATTATCCTCTTGAACCTCTAGTTACTTTAGGTTTTATAATAAATTTATA
ATTTTAATAGGGGGATTTAG

Downstream 100 bases:

>100_bases
GAATAGATTTTATGAGTGCTTAGCTTCATCGAAATAATGCTATAGACCTTTCATTGAAGGAGGGGAATATTGGGGAGAGT
TACGTTTGTTATTGCTTTAT

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKKDKKFSIGEFSEKTGIPIPTLHYYDEIGLLQPEKNPASGHRIYKYQDIITLQKILSLKFLGYSLDKVANLLHESSFGV
DLNESLSLHLQVLEREQEQIEQSMQAMKRVMKLVEEECEIDSTVLFSLIYGMNTEHTHKEWMKRHGLTDIVEELSKKREE
DKIALDQTFIQLSKKVKQLYGKPVEDSKVQEMVKEYIEESFSFLSEDLIQKLANTSVEELDMQELENMIPSPFTEDEQKW
LNEAMEYYVKQVEME

Sequences:

>Translated_255_residues
MKKDKKFSIGEFSEKTGIPIPTLHYYDEIGLLQPEKNPASGHRIYKYQDIITLQKILSLKFLGYSLDKVANLLHESSFGV
DLNESLSLHLQVLEREQEQIEQSMQAMKRVMKLVEEECEIDSTVLFSLIYGMNTEHTHKEWMKRHGLTDIVEELSKKREE
DKIALDQTFIQLSKKVKQLYGKPVEDSKVQEMVKEYIEESFSFLSEDLIQKLANTSVEELDMQELENMIPSPFTEDEQKW
LNEAMEYYVKQVEME
>Mature_255_residues
MKKDKKFSIGEFSEKTGIPIPTLHYYDEIGLLQPEKNPASGHRIYKYQDIITLQKILSLKFLGYSLDKVANLLHESSFGV
DLNESLSLHLQVLEREQEQIEQSMQAMKRVMKLVEEECEIDSTVLFSLIYGMNTEHTHKEWMKRHGLTDIVEELSKKREE
DKIALDQTFIQLSKKVKQLYGKPVEDSKVQEMVKEYIEESFSFLSEDLIQKLANTSVEELDMQELENMIPSPFTEDEQKW
LNEAMEYYVKQVEME

Specific function: Transcriptional activator. Is activated when bound to the antibiotic thiostrepton [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 29926; Mature: 29926

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKDKKFSIGEFSEKTGIPIPTLHYYDEIGLLQPEKNPASGHRIYKYQDIITLQKILSLK
CCCCCCCCCCCCHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FLGYSLDKVANLLHESSFGVDLNESLSLHLQVLEREQEQIEQSMQAMKRVMKLVEEECEI
HHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSTVLFSLIYGMNTEHTHKEWMKRHGLTDIVEELSKKREEDKIALDQTFIQLSKKVKQLY
HHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKPVEDSKVQEMVKEYIEESFSFLSEDLIQKLANTSVEELDMQELENMIPSPFTEDEQKW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHH
LNEAMEYYVKQVEME
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKDKKFSIGEFSEKTGIPIPTLHYYDEIGLLQPEKNPASGHRIYKYQDIITLQKILSLK
CCCCCCCCCCCCHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FLGYSLDKVANLLHESSFGVDLNESLSLHLQVLEREQEQIEQSMQAMKRVMKLVEEECEI
HHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSTVLFSLIYGMNTEHTHKEWMKRHGLTDIVEELSKKREEDKIALDQTFIQLSKKVKQLY
HHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKPVEDSKVQEMVKEYIEESFSFLSEDLIQKLANTSVEELDMQELENMIPSPFTEDEQKW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHH
LNEAMEYYVKQVEME
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]