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The map label for this gene is kipI [H]

Identifier: 52142432

GI number: 52142432

Start: 2924968

End: 2925681

Strand: Reverse

Name: kipI [H]

Synonym: BCZK2810

Alternate gene names: 52142432

Gene position: 2925681-2924968 (Counterclockwise)

Preceding gene: 52142430

Following gene: 52142433

Centisome position: 55.19

GC content: 38.8

Gene sequence:

>714_bases
ATGAAATTTTCTGCGTTAGGGGATCAAGCAATTATTGTTACATTTGGTGAAGGAATTGAAATGGATACTTACGAAAAAGT
GCAGCGACTATTTCAAGCGTTGCAGCAACATCCGTTTACAGGAATGATTGAATGCGTTCCGTCATTTACTTCATTGGCCG
TTTACTATAATTTGTATGAAGTATGGAAGGGAAATGATAGAAAGATAAGACCGTATGATTACGTATGCCAATACATAGCT
AGAATGTTAGATACGTATAAGGAAGAGCTGAAACGAGATGTGAAACATATTTCTATACCCGTTTGTTACGGGGGAGAATA
TGGACCTGATTTAGAAGAGGTGGCACATTATCACGGTTTACAAGTAGAAGATGTCATTCGCATACATAGTGAAACAACGT
ATTTTGTATATATGTTAGGCTTTACACCAGGGTTCCCGTATTTAGGAGGACTATCAAAAGAACTAGAAACACCTAGAAAA
GAAATACCGCGGTTACAAATCTCTCCTGGTTCGGTAGGGATTGGCGGAAATCAAACAGGTATTTATCCGCTTGAAACACC
GGGTGGATGGAATATTATTGGCCGAACACCAATCTCCTTATTTAATCCGGAAGAAGAAACACCAACCTATATTCAAAGCG
GTATGTATTTACGATTTATCCCAATAACGAAGGAAGAGTACGTTTCACTTGAGGGGGCTAAAGAATGGATGTAG

Upstream 100 bases:

>100_bases
ACAGCGAAAGTAACATTCCATATTTTATCGCTAAGGTGAAAGAGACAGCGAATCGCATTTCGAAAGAACTCGGCTTTTTG
GCATAGAAAGAGGGAGTAGG

Downstream 100 bases:

>100_bases
AAGTTTTGCATGCAGGTATGTTTACAACAGTCCAAGATTTAGGACGATCTCATTATCAACAATACGGCGTACCCGTTGGC
GGGGCTATGGATAAAAGTGC

Product: hypothetical protein

Products: NA

Alternate protein names: Sporulation inhibitor kipI [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKFSALGDQAIIVTFGEGIEMDTYEKVQRLFQALQQHPFTGMIECVPSFTSLAVYYNLYEVWKGNDRKIRPYDYVCQYIA
RMLDTYKEELKRDVKHISIPVCYGGEYGPDLEEVAHYHGLQVEDVIRIHSETTYFVYMLGFTPGFPYLGGLSKELETPRK
EIPRLQISPGSVGIGGNQTGIYPLETPGGWNIIGRTPISLFNPEEETPTYIQSGMYLRFIPITKEEYVSLEGAKEWM

Sequences:

>Translated_237_residues
MKFSALGDQAIIVTFGEGIEMDTYEKVQRLFQALQQHPFTGMIECVPSFTSLAVYYNLYEVWKGNDRKIRPYDYVCQYIA
RMLDTYKEELKRDVKHISIPVCYGGEYGPDLEEVAHYHGLQVEDVIRIHSETTYFVYMLGFTPGFPYLGGLSKELETPRK
EIPRLQISPGSVGIGGNQTGIYPLETPGGWNIIGRTPISLFNPEEETPTYIQSGMYLRFIPITKEEYVSLEGAKEWM
>Mature_237_residues
MKFSALGDQAIIVTFGEGIEMDTYEKVQRLFQALQQHPFTGMIECVPSFTSLAVYYNLYEVWKGNDRKIRPYDYVCQYIA
RMLDTYKEELKRDVKHISIPVCYGGEYGPDLEEVAHYHGLQVEDVIRIHSETTYFVYMLGFTPGFPYLGGLSKELETPRK
EIPRLQISPGSVGIGGNQTGIYPLETPGGWNIIGRTPISLFNPEEETPTYIQSGMYLRFIPITKEEYVSLEGAKEWM

Specific function: Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase

COG id: COG2049

COG function: function code E; Allophanate hydrolase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786929, Length=218, Percent_Identity=38.0733944954128, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003833
- InterPro:   IPR020899
- InterPro:   IPR010016
- InterPro:   IPR002130 [H]

Pfam domain/function: PF02682 AHS1 [H]

EC number: NA

Molecular weight: Translated: 27139; Mature: 27139

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSALGDQAIIVTFGEGIEMDTYEKVQRLFQALQQHPFTGMIECVPSFTSLAVYYNLYE
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VWKGNDRKIRPYDYVCQYIARMLDTYKEELKRDVKHISIPVCYGGEYGPDLEEVAHYHGL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHCCC
QVEDVIRIHSETTYFVYMLGFTPGFPYLGGLSKELETPRKEIPRLQISPGSVGIGGNQTG
CHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHCCHHHHCCEEEECCCCEECCCCCCC
IYPLETPGGWNIIGRTPISLFNPEEETPTYIQSGMYLRFIPITKEEYVSLEGAKEWM
EEECCCCCCCEEECCCCCEECCCCCCCCHHHHCCCEEEEEECCHHHHEECCCHHCCC
>Mature Secondary Structure
MKFSALGDQAIIVTFGEGIEMDTYEKVQRLFQALQQHPFTGMIECVPSFTSLAVYYNLYE
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VWKGNDRKIRPYDYVCQYIARMLDTYKEELKRDVKHISIPVCYGGEYGPDLEEVAHYHGL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHCCC
QVEDVIRIHSETTYFVYMLGFTPGFPYLGGLSKELETPRKEIPRLQISPGSVGIGGNQTG
CHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHCCHHHHCCEEEECCCCEECCCCCCC
IYPLETPGGWNIIGRTPISLFNPEEETPTYIQSGMYLRFIPITKEEYVSLEGAKEWM
EEECCCCCCCEEECCCCCEECCCCCCCCHHHHCCCEEEEEECCHHHHEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]